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Hypoglycemia
Open-data reference.
42 US clinical trials · 15 currently recruiting
Active & Recent Trials
Diabetes Clinical Decision Support
Milton S. Hershey Medical Center
NCT05447806
Diagnosing and Treating Low Blood Sugar Levels
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001276
Safer Aging With Diabetes Monitoring
Kaiser Permanente
NCT06296485
Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery
The University of Texas Health Science Center at San Antonio
NCT00992901
Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes
University of Colorado, Denver
NCT06297980
Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes
Indiana University
NCT05643144
Effect of C-peptide on Hypoglycemic Counterregulation
University of Cincinnati
NCT06470295
Differing Levels of Hypoglycemia
University of Maryland, Baltimore
NCT02445781
Monitoring Exhaled Breath to Noninvasively Detect Glycemic Events
Indiana University
NCT06893341
A Study of Glycemic Control in Left Ventricular Assist
Mayo Clinic
NCT05933161
A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
Otsuka Pharmaceutical Factory
NCT06575426
Effect of Fasting on Hypoglycemic Counterregulation in Type 1 Diabetes
University of Cincinnati
NCT05973799
Evaluating Glial Acetate Metabolism as a Biomarker of Hypoglycemic Counterregulation
Pennington Biomedical Research Center
NCT04207619
CGM-Assisted Management of PN
Boston Children's Hospital
NCT05902104
External Carotid Blood Flow in Individuals With Post-Bariatric Hypoglycemia
Joslin Diabetes Center
NCT07082478
Continuous Glucose Monitoring Devices in Hospitalized Veterans With Diabetes
VA Office of Research and Development
NCT03508934
Study of a Primary Care Hypoglycemia Prevention Program
Johns Hopkins University
NCT06353217
Mechanisms of Hypoglycemia in Patients Without Diabetes
Joslin Diabetes Center
NCT04428723
Hypoglycemia and the Gut Microbiome
Joslin Diabetes Center
NCT03385707
Glucagon Dose-Response in Patients With Post-Bariatric Hypoglycemia
Joslin Diabetes Center
NCT06986603
Adrenergic System in Islet Transplantation
University of Pennsylvania
NCT03079921
Identifying Driving Risk Factors in Type 1 Diabetes and Their Reduction Via Internet Program (DiabetesDriving.Com)
University of Virginia
NCT01563887
Carnitine Levels and Carnitine Supplementation in Type I Diabetes
Children's Mercy Hospital Kansas City
NCT00351234
Multi-Center Study Comparing Efficacy and Safety of Frequently Modified Insulin Therapy
Hygieia Research
NCT02424500
Technological Advances in Glucose Management in Older Adults
Joslin Diabetes Center
NCT03078491
Investigation Into the Effects Upon Brain Response to Change in Circulating Glucose Levels in Diabetes Mellitus
Yale University
NCT00580710
GLP 1 for Intraoperative Glycemic Control
University of Pennsylvania
NCT00882492
Outcomes Study of MTM in a Medicare ACO
HealthEast Care System
NCT02875925
Comparison Between Pyloric Preserving and Non-Pyloric Preserving Bariatric Surgery With Glucose Challenge
Medtronic - MITG
NCT00998374
Hypoglycemia in Hospitalized Patients
University of Pittsburgh
NCT02228642
Hippocampal Metabolism and Function in Patients With Type 1 Diabetes
University of Minnesota
NCT01852968
Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in T1DM Children
Zealand Pharma
NCT03667053
Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of G-Pen(TM) (Glucagon Injection) to Treat Severe Hypoglycemia
Xeris Pharmaceuticals
NCT01972152
Clinical Usability of Nasal Glucagon in Treatment of Hypoglycemia in Children and Adolescents
Eli Lilly and Company
NCT02402933
Hypoglycemia and the Mineralocorticoid Receptor
Brigham and Women's Hospital
NCT01394627
Hypoglycemia and Autonomic Nervous System Function- B2
Brigham and Women's Hospital
NCT03422471
Hybrid Closed Loop Insulin Delivery System in Hypoglycemia
University of Pennsylvania
NCT03215914
Delivery of G-Pump™ (Glucagon Infusion) From an OmniPod® to Prevent Hypoglycemia in Post-Bariatric Surgery Patients
Xeris Pharmaceuticals
NCT02733588
G-Pen™ for Hypoglycemia Rescue in T1D Patients
Xeris Pharmaceuticals
NCT02423980
hOKT3γ1 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients
University of Minnesota
NCT00285194
The Effect of Physical Activity in Individuals With Post-bariatric Hypoglycemia
Joslin Diabetes Center
NCT05560789
Disorders of Systemic Glucose Balance
National Center for Research Resources (NCRR)
NCT00006508
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 7 |
| Phase 2 | 3 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Hypoglycemia Trial Landscape
ClinicalTrials.gov lists 42 US studies indexed under Hypoglycemia, and 15 of those are currently open to recruitment — roughly 36% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Hypoglycemia shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 10 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Hypoglycemia is led by Joslin Diabetes Center with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 42 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Hypoglycemia?
PlainTrial tracks 42 US clinical trials for Hypoglycemia, of which 15 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Hypoglycemia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.