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Hypoglycemia: early-phase trial registry
15 of 42 indexed Hypoglycemia trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #347 of 28,707 conditions by registered trial count.
42 US clinical trials · 15 currently recruiting · #347 of 28,707 conditions by registered trial count
Hypoglycemia: 42 US clinical trials tracked, 15 recruiting.
Hypoglycemia is the subject of 42 registered US clinical trials on ClinicalTrials.gov, 15 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Joslin Diabetes Center, running 6 of these trials.
Enrollment posture brief
Registry condition hypoglycemia
OPEN 15 | RECR 36% | LATE 3 | EARLY 10 | RANK #347 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Acute Respiratory Failure (36% recruiting · 14 trials)
Hypoglycemia lists 15 open slots (36% of 42 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Hypoglycemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Hypoglycemia is recruiting below its size-band peers.
15 of 42 indexed trials (35.7%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Hypoglycemia trials is spread across many organizations.
Joslin Diabetes Center accounts for 6 of 42 trials (14.3%). 29 distinct sponsors appear on at least one study for this condition label.
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Most Hypoglycemia trials plan to enrol fewer than 100 people.
Median target enrolment is 33 among the 41 trials that report a genuine target (sentinel values excluded). 30 of those (73.2%) plan for fewer than 100 participants.
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Hypoglycemia research is mostly interventional.
31 interventional and 11 observational studies make up this index (73.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
42 total, page 1 of 1
Diabetes Clinical Decision Support
Milton S. Hershey Medical Center
NCT05447806
Diagnosing and Treating Low Blood Sugar Levels
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001276
Safer Aging With Diabetes Monitoring
Kaiser Permanente
NCT06296485
Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery
The University of Texas Health Science Center at San Antonio
NCT00992901
Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes
University of Colorado, Denver
NCT06297980
Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes
Indiana University
NCT05643144
Effect of C-peptide on Hypoglycemic Counterregulation
University of Cincinnati
NCT06470295
Differing Levels of Hypoglycemia
University of Maryland, Baltimore
NCT02445781
Monitoring Exhaled Breath to Noninvasively Detect Glycemic Events
Indiana University
NCT06893341
A Study of Glycemic Control in Left Ventricular Assist
Mayo Clinic
NCT05933161
A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
Otsuka Pharmaceutical Factory
NCT06575426
Effect of Fasting on Hypoglycemic Counterregulation in Type 1 Diabetes
University of Cincinnati
NCT05973799
Evaluating Glial Acetate Metabolism as a Biomarker of Hypoglycemic Counterregulation
Pennington Biomedical Research Center
NCT04207619
CGM-Assisted Management of PN
Boston Children's Hospital
NCT05902104
External Carotid Blood Flow in Individuals With Post-Bariatric Hypoglycemia
Joslin Diabetes Center
NCT07082478
Continuous Glucose Monitoring Devices in Hospitalized Veterans With Diabetes
VA Office of Research and Development
NCT03508934
Study of a Primary Care Hypoglycemia Prevention Program
Johns Hopkins University
NCT06353217
Mechanisms of Hypoglycemia in Patients Without Diabetes
Joslin Diabetes Center
NCT04428723
Hypoglycemia and the Gut Microbiome
Joslin Diabetes Center
NCT03385707
Glucagon Dose-Response in Patients With Post-Bariatric Hypoglycemia
Joslin Diabetes Center
NCT06986603
Adrenergic System in Islet Transplantation
University of Pennsylvania
NCT03079921
Identifying Driving Risk Factors in Type 1 Diabetes and Their Reduction Via Internet Program (DiabetesDriving.Com)
University of Virginia
NCT01563887
Carnitine Levels and Carnitine Supplementation in Type I Diabetes
Children's Mercy Hospital Kansas City
NCT00351234
Multi-Center Study Comparing Efficacy and Safety of Frequently Modified Insulin Therapy
Hygieia Research
NCT02424500
Technological Advances in Glucose Management in Older Adults
Joslin Diabetes Center
NCT03078491
Investigation Into the Effects Upon Brain Response to Change in Circulating Glucose Levels in Diabetes Mellitus
Yale University
NCT00580710
GLP 1 for Intraoperative Glycemic Control
University of Pennsylvania
NCT00882492
Outcomes Study of MTM in a Medicare ACO
HealthEast Care System
NCT02875925
Comparison Between Pyloric Preserving and Non-Pyloric Preserving Bariatric Surgery With Glucose Challenge
Medtronic - MITG
NCT00998374
Hypoglycemia in Hospitalized Patients
University of Pittsburgh
NCT02228642
Hippocampal Metabolism and Function in Patients With Type 1 Diabetes
University of Minnesota
NCT01852968
Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in T1DM Children
Zealand Pharma
NCT03667053
Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of G-Pen(TM) (Glucagon Injection) to Treat Severe Hypoglycemia
Xeris Pharmaceuticals
NCT01972152
Clinical Usability of Nasal Glucagon in Treatment of Hypoglycemia in Children and Adolescents
Eli Lilly and Company
NCT02402933
Hypoglycemia and the Mineralocorticoid Receptor
Brigham and Women's Hospital
NCT01394627
Hypoglycemia and Autonomic Nervous System Function- B2
Brigham and Women's Hospital
NCT03422471
Hybrid Closed Loop Insulin Delivery System in Hypoglycemia
University of Pennsylvania
NCT03215914
Delivery of G-Pump™ (Glucagon Infusion) From an OmniPod® to Prevent Hypoglycemia in Post-Bariatric Surgery Patients
Xeris Pharmaceuticals
NCT02733588
G-Pen™ for Hypoglycemia Rescue in T1D Patients
Xeris Pharmaceuticals
NCT02423980
hOKT3γ1 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients
University of Minnesota
NCT00285194
The Effect of Physical Activity in Individuals With Post-bariatric Hypoglycemia
Joslin Diabetes Center
NCT05560789
Disorders of Systemic Glucose Balance
National Center for Research Resources (NCRR)
NCT00006508
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 3 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Hypoglycemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Hypoglycemia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Hypoglycemia page
42 registered trials, 15 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 15 Hypoglycemia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Joslin Diabetes Center sponsors the most Hypoglycemia trials on record, review their full trial history before evaluating a specific study. See Joslin Diabetes Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypoglycemia condition card totals 42 registered trials; most-linked intervention Placebo; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.