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NCT04428723 · ClinicalTrials.gov registry record
Mechanisms of Hypoglycemia in Patients Without Diabetes
A clinical trial of Hypoglycemia, sponsored by Joslin Diabetes Center.
- Active
- Registry status
- 33
- Enrollment target
- 1
- Study location
NCT04428723: Active study of Hypoglycemia, sponsored by Joslin Diabetes Center.
NCT04428723 is a study of Hypoglycemia that is active but no longer recruiting, run by Joslin Diabetes Center. The registered enrollment target is 33 participants, below the 506-participant average among 40 other Hypoglycemia trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04428723, a study of Hypoglycemia, is active but no longer recruiting, sponsored by Joslin Diabetes Center.
- ACTIVE NOT RECRUITING
- Registry status
- 33 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to identify physiologic and molecular mechanisms that underlie hypoglycemia in the absence of diabetes (or medications that can cause hypoglycemia) and to investigate potential genetic and microbiome differences which contribute to hypoglycemia. We will test the hypothesis that hypoglycemia in the absence of diabetes is linked to genetic variation or the microbiome, and identify whether additional medical history or diagnoses are enriched in the population of patients with hypoglycemia.
Primary Outcome
Medical history data will be entered into RedCap for analysis.
Conditions Studied
Interventions
- GENETIC Blood sample for DNA analysis
- OTHER Entry of demographic and medical history data into a deidentified database
- DIAGNOSTIC_TEST Stool sample for microbiome analysis
- DIAGNOSTIC_TEST Mixed meal tolerance test
- DIAGNOSTIC_TEST Continuous glucose monitoring
Study Locations (1)
Massachusetts
- Joslin Diabetes Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2020-08-11 |
| Est. Completion | 2026-12 |
What the registry record for NCT04428723 still lists
NCT04428723 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 506-participant average among 40 other Hypoglycemia trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Hypoglycemia appearing as the primary indexed condition, and to 5 interventions - of which Blood sample for DNA analysis is the first listed.
NCT04428723 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04428723 about?
NCT04428723 is a clinical study titled "Mechanisms of Hypoglycemia in Patients Without Diabetes". The goal of this study is to identify physiologic and molecular mechanisms that underlie hypoglycemia in the absence of diabetes (or medications that can cause hypoglycemia) and to investigate potential genetic and microbiome differences which contribute to hypoglycemia. We will test the hypothesis ...
What is the current status of trial NCT04428723?
This trial is currently active not recruiting. The enrollment target is 33 participants. The study started on 2020-08-11. Estimated completion is 2026-12.
What conditions does trial NCT04428723 study?
This clinical trial studies the following conditions: Hypoglycemia.
What interventions are being tested in trial NCT04428723?
The interventions under investigation include: Blood sample for DNA analysis (GENETIC), Entry of demographic and medical history data into a deidentified database (OTHER), Stool sample for microbiome analysis (DIAGNOSTIC_TEST), Mixed meal tolerance test (DIAGNOSTIC_TEST), Continuous glucose monitoring (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04428723?
This trial is sponsored by Joslin Diabetes Center, which has 73 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04428723 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypoglycemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04428723's enrollment target sits among peer trials
33 21st of 40 higher than 20 of 40 other Hypoglycemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypoglycemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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