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NCT06973005 · ClinicalTrials.gov registry record · Phase 1
A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants
A Phase 1 study of Healthy Participants and Advanced Chronic Liver Disease, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT06973005 is a Phase 1 study of Healthy Participants and Advanced Chronic Liver Disease that has completed, run by AstraZeneca. The registered enrollment target is 16 participants, below the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06973005, a Phase 1 study of Healthy Participants and Advanced Chronic Liver Disease, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to measure the effect of multiple doses of AZD2389 on the pharmacokinetics (PK) of midazolam, caffeine, and bupropion in healthy participants.
Conditions Studied
Interventions
- DRUG Midazolam
- DRUG Caffeine
- DRUG Bupropion
- DRUG AZD2389
Study Locations (1)
Maryland
- Research Site - Brooklyn
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2025-05-08 |
| Est. Completion | 2025-07-18 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06973005
The ClinicalTrials.gov registry entry for NCT06973005 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (75% lower). The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Healthy Participants appearing as the primary indexed condition, and to 4 interventions - of which Midazolam is the first listed.
NCT06973005 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT06973005 about?
NCT06973005 is a clinical study titled "A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants". The purpose of this study is to measure the effect of multiple doses of AZD2389 on the pharmacokinetics (PK) of midazolam, caffeine, and bupropion in healthy participants.
What is the current status of trial NCT06973005?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2025-05-08. Estimated completion is 2025-07-18.
What conditions does trial NCT06973005 study?
This clinical trial studies the following conditions: Healthy Participants, Advanced Chronic Liver Disease.
What interventions are being tested in trial NCT06973005?
The interventions under investigation include: Midazolam (DRUG), Caffeine (DRUG), Bupropion (DRUG), AZD2389 (DRUG).
Who is sponsoring clinical trial NCT06973005?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06973005 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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