Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01064739 · ClinicalTrials.gov registry record · Early Phase 1
Renal Salt Handling in Postural Tachycardia Syndrome Following Dietary Dopa Administration
A Early Phase 1 study of Healthy Participants, sponsored by Vanderbilt University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 14
- Enrollment target
- 1
- Study location
NCT01064739 is a Early Phase 1 study of Healthy Participants that has completed, run by Vanderbilt University. The registered enrollment target is 14 participants, below the 66-participant average among 119 other Healthy Participants trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01064739, a Early Phase 1 study of Healthy Participants, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 14 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to learn how plants can play a role in gain/loss of sodium in the urine and in the regulation of blood pressure. Dopamine is a chemical mostly present in the brain and kidneys which assists in regulation of the body's salts (sodium and potassium). Fava beans contain a lot of the chemical that increases the production of dopamine by the kidneys. The purpose of these studies is to characterize the diuretic effects of dietary catecholamine sources in healthy individuals. Specific aims are: 1. To determine the effect of dietary dopa sources on plasma and urinary catecholamines. 2. To investigate the capacity of botanical dopaminergic agents (fava beans) to induce natriuresis in a short term study. 3. To provide preliminary data on the effects of dietary dopa on heart rate and blood pressure. In these studies, we will test the null hypothesis (Ho) that urinary sodium excretion will not differ in healthy volunteers after consumption of a fixed-sodium study diet and the study diet plus fava beans.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Fava beans
- OTHER Fixed Sodium Diet
Study Locations (1)
Tennessee
- Vanderbilt University Clinical Research Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2007-01 |
| Est. Completion | 2012-12 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01064739
The ClinicalTrials.gov registry entry for NCT01064739 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 66-participant average among 119 other Healthy Participants trials with a reported enrollment target (79% lower). The listed sponsor is Vanderbilt University, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 2 interventions - of which Fava beans is the first listed.
NCT01064739 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT01064739 about?
NCT01064739 is a clinical study titled "Renal Salt Handling in Postural Tachycardia Syndrome Following Dietary Dopa Administration". The purpose of this study is to learn how plants can play a role in gain/loss of sodium in the urine and in the regulation of blood pressure. Dopamine is a chemical mostly present in the brain and kidneys which assists in regulation of the body's salts (sodium and potassium). Fava beans contain a lo...
What is the current status of trial NCT01064739?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 14 participants. The study started on 2007-01. Estimated completion is 2012-12.
What conditions does trial NCT01064739 study?
This clinical trial studies the following conditions: Healthy Participants.
What interventions are being tested in trial NCT01064739?
The interventions under investigation include: Fava beans (DIETARY_SUPPLEMENT), Fixed Sodium Diet (OTHER).
Who is sponsoring clinical trial NCT01064739?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01064739 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Participants
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
First-in-Human Study for the Safety and Evaluation of Two 4R Tau Ligands as Potential PET Radioligands for Imaging Tau Protein in the Brain
RECRUITING · Early Phase 1
-
Researching Economical Adjuvants to Cancer Therapy
RECRUITING · Early Phase 1
-
Single and Multiple Ascending Doses of NTX-253 in Healthy Participants and Participants With Stable Schizophrenia
RECRUITING · Early Phase 1
-
Washington University WU 409: Immune Responses to Rabies Vaccine.
COMPLETED · Early Phase 1
-
A Study to Assess the Bioequivalence of Trastuzumab Via Different Subcutaneous Delivery Platforms in Healthy Male Participants
RECRUITING · Phase 1
-
Impact of Exogenous Ketones on Sleep and Breathing in Healthy Volunteers (K-SLEEP)
RECRUITING · Phase 1
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.