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NCT05129475 · ClinicalTrials.gov registry record · Phase 1
Food Effect Study to Evaluate the Effect of High-Fat Meal on the Relative Bioavailability of PF-07321332 Boosted With Ritonavir in Healthy Adult Participants
A Phase 1 study of Healthy Participants, sponsored by Pfizer.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT05129475: Completed Phase 1 study of Healthy Participants, sponsored by Pfizer.
NCT05129475 is a Phase 1 study of Healthy Participants that has completed, run by Pfizer. The registered enrollment target is 12 participants, below the 66-participant average among 119 other Healthy Participants trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05129475, a Phase 1 study of Healthy Participants, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a Phase 1, open label, single dose, randomized, 2-treatment, 2-sequence, 2-period crossover study to evaluate the effect of high-fat meal on the relative bioavailability of PF-07321332 boosted with ritonavir following single dose oral administration of PF-07321332 in combination with ritonavir using 150 mg tablet formulation of PF-07321332 in healthy adult participants.
Primary Outcome
Area under the plasma concentration-time profile from time zero to the time of the last quantifiable concentration was determined by linear/log trapezoidal method and reported in this outcome measure.
Conditions Studied
Interventions
- DRUG Ritonavir
- DRUG PF-07321332/ritonavir
Study Locations (1)
Connecticut
- New Haven Clinical Research Unit - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2021-11-12 |
| Est. Completion | 2022-01-12 |
| Phase | Phase 1 |
What the finished NCT05129475 record still lists
NCT05129475 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 66-participant average among 119 other Healthy Participants trials with a reported enrollment target (82% lower).
The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 2 interventions - of which Ritonavir is the first listed.
NCT05129475 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT05129475 about?
NCT05129475 is a clinical study titled "Food Effect Study to Evaluate the Effect of High-Fat Meal on the Relative Bioavailability of PF-07321332 Boosted With Ritonavir in Healthy Adult Participants". This is a Phase 1, open label, single dose, randomized, 2-treatment, 2-sequence, 2-period crossover study to evaluate the effect of high-fat meal on the relative bioavailability of PF-07321332 boosted with ritonavir following single dose oral administration of PF-07321332 in combination with ritonav...
What is the current status of trial NCT05129475?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2021-11-12. Estimated completion is 2022-01-12.
What conditions does trial NCT05129475 study?
This clinical trial studies the following conditions: Healthy Participants.
What interventions are being tested in trial NCT05129475?
The interventions under investigation include: Ritonavir (DRUG), PF-07321332/ritonavir (DRUG).
Who is sponsoring clinical trial NCT05129475?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05129475 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05129475's enrollment target sits among peer trials
12 112th of 119 higher than 6 of 119 other Healthy Participants trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Participants trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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