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NCT06846528 · ClinicalTrials.gov registry record · Phase 1
A Study to Investigate the Pharmacokinetics of AZD2389 When Administered Alone and in Combination With Itraconazole in Healthy Participants
A Phase 1 study of Healthy Participants, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT06846528: Completed Phase 1 study of Healthy Participants, sponsored by AstraZeneca.
NCT06846528 is a Phase 1 study of Healthy Participants that has completed, run by AstraZeneca. The registered enrollment target is 16 participants, below the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06846528, a Phase 1 study of Healthy Participants, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to assess the pharmacokinetics (PK) of AZD2389 when administered alone and in combination with itraconazole in healthy participants.
Primary Outcome
To assess the effect of itraconazole on the Cmax of AZD2389.
Conditions Studied
Interventions
- DRUG Itraconazole
- DRUG AZD2389
Study Locations (1)
Maryland
- Research Site - Brooklyn
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2025-02-26 |
| Est. Completion | 2025-04-23 |
| Phase | Phase 1 |
What the finished NCT06846528 record still lists
NCT06846528 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 65-participant average among 119 other Healthy Participants trials with a reported enrollment target (75% lower).
The record links to 1 condition, with Healthy Participants appearing as the primary indexed condition, and to 2 interventions - of which Itraconazole is the first listed.
NCT06846528 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT06846528 about?
NCT06846528 is a clinical study titled "A Study to Investigate the Pharmacokinetics of AZD2389 When Administered Alone and in Combination With Itraconazole in Healthy Participants". The purpose of this study is to assess the pharmacokinetics (PK) of AZD2389 when administered alone and in combination with itraconazole in healthy participants.
What is the current status of trial NCT06846528?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2025-02-26. Estimated completion is 2025-04-23.
What conditions does trial NCT06846528 study?
This clinical trial studies the following conditions: Healthy Participants.
What interventions are being tested in trial NCT06846528?
The interventions under investigation include: Itraconazole (DRUG), AZD2389 (DRUG).
Who is sponsoring clinical trial NCT06846528?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06846528 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06846528's enrollment target sits among peer trials
16 97th of 119 higher than 16 of 119 other Healthy Participants trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Participants trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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