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ClinicalTrials.gov 49 recruiting now early-phase tilt

Follicular Lymphoma: early-phase trial registry

49 of 90 indexed Follicular Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #153 of 28,707 conditions by registered trial count.

90 US clinical trials · 49 currently recruiting · #153 of 28,707 conditions by registered trial count

Follicular Lymphoma: 90 US clinical trials tracked, 49 recruiting.

Follicular Lymphoma is the subject of 90 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 72 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 4 of these trials.

Enrollment posture brief

Registry condition follicular-lymphoma

OPEN 49 | RECR 54% | LATE 7 | EARLY 72 | RANK #153 | SPON 4

Nearest open-share peer: Advanced Ovarian Carcinoma (55% recruiting · 11 trials)

Follicular Lymphoma (this)54%Substance Use47.2%Glioblastoma Multiforme41.6%Sepsis36.3%Myopia24.2%
Open-enrollment share among volume-matched conditions near Follicular Lymphoma

Follicular Lymphoma lists 49 open slots (54% of 90 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Follicular Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Follicular Lymphoma is recruiting above its size-band peers.

    49 of 90 indexed trials (54.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Follicular Lymphoma trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 4 of 90 trials (4.4%). 64 distinct sponsors appear on at least one study for this condition label.

  3. Most Follicular Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 90 trials that report a genuine target (sentinel values excluded). 57 of those (63.3%) plan for fewer than 100 participants.

  4. Follicular Lymphoma research is mostly interventional.

    84 interventional and 6 observational studies make up this index (93.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 145Phase 227Phase 37

Open and recent trials

90 total, page 1 of 2

RECRUITING Phase 3 700 participants

A Long-term Extension Study of PCI-32765 (Ibrutinib)

Janssen Research & Development

NCT01804686

RECRUITING Phase 1 614 participants

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

BeOne Medicines

NCT05006716

RECRUITING Phase 3 612 participants

A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.

Epizyme

NCT04224493

RECRUITING 500 participants

Long-term Follow-up Study of Patients Receiving CAR-T Cells

Medical College of Wisconsin

NCT03375619

RECRUITING Phase 3 400 participants

A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

Celgene

NCT06911502

RECRUITING Phase 3 375 participants

A Study of Reduced Dose Radiation Therapy for People With B-Cell Lymphomas

Memorial Sloan Kettering Cancer Center

NCT07029217

RECRUITING Phase 1 317 participants

A Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma

AstraZeneca

NCT04594642

RECRUITING 300 participants

A Study to Patients With Relapsed/Refractory Follicular Lymphoma Treated With Liso-cel (Lisocabtagene Maraleucel) in the Post Marketing Setting

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

NCT06794268

RECRUITING 300 participants

Optimizing ctDNA-based MRD Assessment in DLBCL, MCL, and FL Patients Undergoing CAR Therapy

Adaptive Biotechnologies

NCT05255354

RECRUITING 200 participants

Evaluation of Human Immune Responses Vaccination in Patients With Lymphoma

Emory University

NCT03501576

RECRUITING 200 participants

Clonal Evolution in Follicular Lymphoma

National Cancer Institute (NCI)

NCT03190928

RECRUITING NA 200 participants

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT01962636

RECRUITING Phase 1 168 participants

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

OncoNano Medicine

NCT06022029

RECRUITING Phase 1 154 participants

A Study to Assess the Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-319 Moves Through the Bodies of Adult Participants With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), or Chronic Lymphocytic Leukemia (CLL)

AbbVie

NCT05512390

RECRUITING Phase 2 152 participants

A Study of Mosunetuzumab Alone or With Zanubrutinib in People With Follicular Lymphoma

Memorial Sloan Kettering Cancer Center

NCT05389293

RECRUITING Phase 1 148 participants

AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

Stanford University

NCT06340737

RECRUITING Phase 1 140 participants

IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas

Iksuda Therapeutics

NCT05365659

RECRUITING Phase 1 120 participants

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

CRISPR Therapeutics

NCT05643742

RECRUITING Phase 1 120 participants

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

Carna Biosciences

NCT05602363

RECRUITING Phase 1 100 participants

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

Medical College of Wisconsin

NCT04186520

RECRUITING Phase 2 100 participants

Epcoritamab and Rituximab for First-line Follicular Lymphoma

Reid Merryman, MD

NCT05783609

RECRUITING Phase 2 100 participants

Loncastuximab Tesirine in Combination With Rituximab in Patients With Relapsed or Refractory Follicular Lymphoma

Juan P. Alderuccio, MD

NCT04998669

RECRUITING Phase 1 100 participants

Measuring Cell-Free DNA (cfDNA) Levels in People With Follicular Lymphoma

Memorial Sloan Kettering Cancer Center

NCT04468841

RECRUITING Phase 1 98 participants

Study of SGR-1505 in Mature B-Cell Neoplasms

Schrödinger

NCT05544019

RECRUITING Phase 1 80 participants

A Novel Vaccine (EO2463) as Monotherapy and in Combination, for Treatment of Patients With Indolent Non-Hodgkin Lymphoma

Enterome

NCT04669171

RECRUITING Phase 2 65 participants

HM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZL

Masonic Cancer Center, University of Minnesota

NCT06792825

RECRUITING Phase 1 60 participants

Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.

Newave Pharmaceutical

NCT04775745

RECRUITING Phase 2 52 participants

Mosunetuzumab With Lenalidomide Augmentation as First-line Therapy for Follicular and Marginal Zone Lymphoma

Brown University

NCT04792502

RECRUITING Phase 2 50 participants

Tazemetostat and Mosunetuzumab in Untreated Follicular Lymphoma

Weill Medical College of Cornell University

NCT05994235

RECRUITING 45 participants

Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment

OHSU Knight Cancer Institute

NCT06784167

RECRUITING Phase 2 45 participants

Epco, Zanu, Ritux for R/R FL or MZL

Reid Merryman, MD

NCT06563596

RECRUITING Phase 2 43 participants

Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas

H. Lee Moffitt Cancer Center and Research Institute

NCT06350318

RECRUITING Phase 1 42 participants

ACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies

Acepodia Biotech

NCT05653271

RECRUITING Early Phase 1 42 participants

64Cu-LLP2A for Imaging Hematologic Malignancies

Washington University School of Medicine

NCT06636175

RECRUITING NA 40 participants

Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

UNC Lineberger Comprehensive Cancer Center

NCT06860880

RECRUITING Phase 1 38 participants

Tazemetostat and Venetoclax in Relapsed/Refractory Non-Hodgkin Lymphoma

Weill Medical College of Cornell University

NCT05618366

RECRUITING Phase 2 36 participants

Phase 2 Trial of Obinutuzumab and CC-99282 for Patients With Previously Untreated High Tumor Burden Follicular Lymphoma

M.D. Anderson Cancer Center

NCT06108232

RECRUITING Phase 1 36 participants

Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma

C. Babis Andreadis

NCT04545762

RECRUITING Phase 2 35 participants

Epcoritamab in Patients With Follicular Lymphoma Not Accomplishing a CR With Upfront Chemoimmunotherapy

Beth Israel Deaconess Medical Center

NCT06510361

RECRUITING Phase 2 35 participants

Odronextamab in Low Tumor Volume Advanced FL

Gottfried von Keudell, MD PhD

NCT07128641

RECRUITING Phase 1 32 participants

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

Vironexis Biotherapeutics

NCT06533579

RECRUITING Phase 2 30 participants

Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia

John Lister

NCT05281809

RECRUITING Phase 2 28 participants

Emapalumab Prevention of CAR-T Cell Associated Toxicities

Marcela V. Maus, M.D.,Ph.D.

NCT06550141

RECRUITING Phase 1 24 participants

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

Marcela V. Maus, M.D.,Ph.D.

NCT06026319

RECRUITING Phase 2 20 participants

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

M.D. Anderson Cancer Center

NCT06043323

RECRUITING Phase 1 20 participants

Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

UNC Lineberger Comprehensive Cancer Center

NCT04223765

RECRUITING Phase 1 18 participants

SynKIR-310 for Relapsed/Refractory B-NHL

Verismo Therapeutics

NCT06544265

RECRUITING Phase 1 15 participants

A Feasibility Trial of Tazemetostat Plus CAR T Cell Therapy in B-cell Lymphomas

Weill Medical College of Cornell University

NCT05934838

RECRUITING Phase 1 12 participants

LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

Medical College of Wisconsin

NCT05990465

ACTIVE NOT RECRUITING Phase 3 654 participants

A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.

Incyte Corporation

NCT04680052

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Phase Distribution

PhaseTrial count
Phase 1 45
Phase 2 27
Phase 3 7

Named interventions

Most-linked intervention names on Follicular Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cyclophosphamide Drug
12 trials
Rituximab Drug
11 trials
Fludarabine Drug
9 trials
Lenalidomide Drug
5 trials
Bendamustine Drug
4 trials
Mosunetuzumab Drug
4 trials
Obinutuzumab Drug
4 trials
Tazemetostat Drug
3 trials

US sites by state

Facility locations filed on Follicular Lymphoma trials. A trial with sites in several states counts in each.

New York 27 trials
California 24 trials
Texas 23 trials
Massachusetts 23 trials
Florida 19 trials
Ohio 15 trials
New Jersey 13 trials
North Carolina 13 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Follicular Lymphoma page

90 registered trials, 49 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Follicular Lymphoma condition card totals 90 registered trials; most-linked intervention Cyclophosphamide; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.