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NCT06043323 · ClinicalTrials.gov registry record · Phase 2

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

A Phase 2 study of Follicular Lymphoma, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
20
Enrollment target
1
Study location

NCT06043323: Recruiting Phase 2 study of Follicular Lymphoma, sponsored by M.D. Anderson Cancer Center.

NCT06043323 is a Phase 2 study of Follicular Lymphoma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 20 participants, below the 135-participant average among 89 other Follicular Lymphoma trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06043323, a Phase 2 study of Follicular Lymphoma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

To learn about the safety of a drug called axicabtagene ciloleucel given in combination with radiation therapy to patients with relapsed/refractory FL.

Conditions Studied

Interventions

  • DRUG Cyclophosphamide
  • DRUG Fludarabine phosphate
  • DRUG Prednisone
  • DRUG Axicabtagene Ciloleucel
  • DRUG Diphenhydramine

Study Locations (1)

Texas

  • MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-01-08
Est. Completion 2028-09-01
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

What NCT06043323 shows while recruiting

NCT06043323 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 135-participant average among 89 other Follicular Lymphoma trials with a reported enrollment target (85% lower).

The record links to 1 condition, with Follicular Lymphoma appearing as the primary indexed condition, and to 5 interventions - of which Cyclophosphamide is the first listed.

NCT06043323 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT06043323 about?

NCT06043323 is a clinical study titled "A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma". To learn about the safety of a drug called axicabtagene ciloleucel given in combination with radiation therapy to patients with relapsed/refractory FL.

What is the current status of trial NCT06043323?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2024-01-08. Estimated completion is 2028-09-01.

What conditions does trial NCT06043323 study?

This clinical trial studies the following conditions: Follicular Lymphoma.

What interventions are being tested in trial NCT06043323?

The interventions under investigation include: Cyclophosphamide (DRUG), Fludarabine phosphate (DRUG), Prednisone (DRUG), Axicabtagene Ciloleucel (DRUG), Diphenhydramine (DRUG).

Who is sponsoring clinical trial NCT06043323?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06043323 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Follicular Lymphoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06043323's enrollment target sits among peer trials

20 81st of 89 higher than 7 of 89 other Follicular Lymphoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Follicular Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06043323, the US trial registry maintained by the National Library of Medicine. NCT06043323 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.