Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 49 recruiting now early-phase tilt

Follicular Lymphoma: early-phase trial registry

49 of 90 indexed Follicular Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #153 of 28,707 conditions by registered trial count.

90 US clinical trials · 49 currently recruiting · #153 of 28,707 conditions by registered trial count

Follicular Lymphoma: 90 US clinical trials tracked, 49 recruiting.

Follicular Lymphoma is the subject of 90 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 72 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 4 of these trials.

Enrollment posture brief

Registry condition follicular-lymphoma

OPEN 49 | RECR 54% | LATE 7 | EARLY 72 | RANK #153 | SPON 4

Nearest open-share peer: Advanced Ovarian Carcinoma (55% recruiting · 11 trials)

Follicular Lymphoma (this)54%Substance Use47.2%Glioblastoma Multiforme41.6%Sepsis36.3%Myopia24.2%
Open-enrollment share among volume-matched conditions near Follicular Lymphoma

Follicular Lymphoma lists 49 open slots (54% of 90 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Follicular Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Follicular Lymphoma is recruiting above its size-band peers.

    49 of 90 indexed trials (54.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Follicular Lymphoma trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 4 of 90 trials (4.4%). 64 distinct sponsors appear on at least one study for this condition label.

  3. Most Follicular Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 90 trials that report a genuine target (sentinel values excluded). 57 of those (63.3%) plan for fewer than 100 participants.

  4. Follicular Lymphoma research is mostly interventional.

    84 interventional and 6 observational studies make up this index (93.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 145Phase 227Phase 37

Open and recent trials

90 total, page 2 of 2

ACTIVE NOT RECRUITING Phase 1 543 participants

Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)

Genmab

NCT04663347

ACTIVE NOT RECRUITING Phase 1 237 participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma

Hoffmann-La Roche

NCT04246086

ACTIVE NOT RECRUITING Phase 2 223 participants

A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)

Merck Sharp & Dohme

NCT05458297

ACTIVE NOT RECRUITING Phase 1 190 participants

A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)

NCT03162536

ACTIVE NOT RECRUITING Phase 2 139 participants

Study of Abexinostat in Patients With Relapsed or Refractory Follicular Lymphoma

Xynomic Pharmaceuticals

NCT03600441

ACTIVE NOT RECRUITING Phase 2 47 participants

Glofit and Obin in Follicular Lymphoma and Marginal Zone Lymphoma

Reid Merryman, MD

NCT05783596

ACTIVE NOT RECRUITING Phase 1 43 participants

Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

University of Michigan Rogel Cancer Center

NCT03842696

ACTIVE NOT RECRUITING Phase 1 42 participants

A Study of Tazemetostat With Rituximab and Abbreviated Bendamustine in the Frontline Treatment of High Tumor Burden Follicular Lymphoma

Vaishalee Kenkre

NCT05551936

ACTIVE NOT RECRUITING Phase 1 36 participants

Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies

Synthekine

NCT05665062

ACTIVE NOT RECRUITING Phase 2 34 participants

Mosunetuzumab and Polatuzumab Vedotin for Untreated Follicular Lymphoma

Washington University School of Medicine

NCT05410418

ACTIVE NOT RECRUITING Phase 2 33 participants

Ixazomib Citrate and Rituximab in Treating Patients With Indolent B-cell Non-Hodgkin Lymphoma

University of Washington

NCT02339922

ACTIVE NOT RECRUITING Phase 2 33 participants

Response-Adapted Therapy With Copanlisib and Rituximab in Untreated Follicular Lymphoma

National Cancer Institute (NCI)

NCT03789240

ACTIVE NOT RECRUITING Phase 1 33 participants

Low Dose Radiation as Bridging Therapy in Relapsed B-Cell Non-Hodgkin Lymphoma

University of Nebraska

NCT05621096

ACTIVE NOT RECRUITING Phase 1 30 participants

A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies

Bio-Path Holdings

NCT04072458

ACTIVE NOT RECRUITING Phase 1 27 participants

Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma

City of Hope Medical Center

NCT03884998

ACTIVE NOT RECRUITING Phase 2 26 participants

Optimizing Cellular and Humoral Immunity by Vaccinating With PCV13 Before and After CAR-T Therapy

H. Lee Moffitt Cancer Center and Research Institute

NCT04745559

ACTIVE NOT RECRUITING Phase 1 20 participants

Personalized Neoantigen Cancer Vaccine + Pembrolizumab After Rituximab for Follicular Lymphoma

Dana-Farber Cancer Institute

NCT03361852

ACTIVE NOT RECRUITING Phase 1 16 participants

Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant

M.D. Anderson Cancer Center

NCT03622788

COMPLETED Phase 3 1,030 participants

Combined Rituximab and Lenalidomide Treatment for Untreated Patients With Follicular Lymphoma

Celgene

NCT01476787

COMPLETED Phase 3 394 participants

A Study Of PF-05280586 (Rituximab-Pfizer) Or MabThera® (Rituximab-EU) For The First-Line Treatment Of Patients With CD20-Positive, Low Tumor Burden, Follicular Lymphoma (REFLECTIONS B328-06)

Pfizer

NCT02213263

COMPLETED Phase 1 134 participants

Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies

National Cancer Institute (NCI)

NCT02315612

COMPLETED Phase 2 125 participants

Efficacy and Safety Study of Idelalisib in Participants With Indolent B-Cell Non-Hodgkin Lymphomas

Gilead Sciences

NCT01282424

COMPLETED Phase 1 96 participants

First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers

Bristol-Myers Squibb

NCT01120457

COMPLETED Phase 1 91 participants

A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Hematologic Malignancies (MK-2140-001)

VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

NCT03833180

COMPLETED Phase 2 73 participants

A Phase II Study of VELCADE (Bortezomib) in Combination With Bendamustine and Rituximab in Subjects With Relapsed or Refractory Follicular Lymphoma

Millennium Pharmaceuticals

NCT00636792

COMPLETED Phase 2 66 participants

VELCADE® (Bortezomib) With Rituximab in Subjects With Relapsed or Refractory Indolent B-Cell Lymphoma

Millennium Pharmaceuticals

NCT00085696

COMPLETED Phase 1 60 participants

Fludarabine, Bendamustine, and Rituximab in Treating Participants With Lymphoid Cancers Undergoing Stem Cell Transplant

M.D. Anderson Cancer Center

NCT00880815

COMPLETED Phase 1 50 participants

Oral Clofarabine for Relapsed/Refractory Non-Hodgkin Lymphoma

Massachusetts General Hospital

NCT00644189

COMPLETED Phase 2 50 participants

Phase II Safety and Efficacy Study of Single-agent AT-101 in Patients With Relapsed or Refractory B-cell Malignancies

Ascenta Therapeutics

NCT00275431

COMPLETED NA 46 participants

Use of a Patient Preferences Shared Decision-Making Encounter Tool in Clinical Practice for Patients With DLBCL and FL

Carevive Systems

NCT04160442

COMPLETED NA 45 participants

Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy

Pack Health

NCT05064787

COMPLETED Phase 1 39 participants

Ph I Trial of NAM NK Cells and IL-2 for Adult Pts With MM and NHL

Masonic Cancer Center, University of Minnesota

NCT03019666

COMPLETED Phase 1 37 participants

A Phase I/II Trial of VR-CHOP in Lymphoma Patients

Emory University

NCT00634179

COMPLETED Phase 1 26 participants

BR101801 in Adult Patients With Advanced Hematologic Malignancies(Phase I)

Boryung Pharmaceutical Co.

NCT04018248

COMPLETED Phase 1 24 participants

Vaccination for the Treatment of Previously Untreated or Relapsed Follicular Lymphoma

Dana-Farber Cancer Institute

NCT00487305

COMPLETED Phase 2 23 participants

Safety & Efficacy Study of AT-101 in Combination w/ Rituximab in Previously Untreated Grade I-II Follicular Non-Hodgkin's Lymphoma

Ascenta Therapeutics

NCT00440388

COMPLETED Phase 2 22 participants

Imexon for Relapsed Follicular and Aggressive Lymphomas

University of Rochester

NCT01314014

COMPLETED Phase 1 11 participants

Venetoclax With Obinutuzumab and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-cell Malignancies

National Cancer Institute (NCI)

NCT04599634

COMPLETED NA 10 participants

Adaptive Bridging RT in R/R B-cell Lymphoma (Pre-CAR T)

Massachusetts General Hospital

NCT06004167

COMPLETED Phase 1 6 participants

TC-110 T Cells in Adults With Relapsed or Refractory Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia

TCR2 Therapeutics

NCT04323657

← Previous Page 2 of 2

Phase Distribution

PhaseTrial count
Phase 1 45
Phase 2 27
Phase 3 7

Named interventions

Most-linked intervention names on Follicular Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cyclophosphamide Drug
12 trials
Rituximab Drug
11 trials
Fludarabine Drug
9 trials
Lenalidomide Drug
5 trials
Bendamustine Drug
4 trials
Mosunetuzumab Drug
4 trials
Obinutuzumab Drug
4 trials
Tazemetostat Drug
3 trials

US sites by state

Facility locations filed on Follicular Lymphoma trials. A trial with sites in several states counts in each.

New York 27 trials
California 24 trials
Texas 23 trials
Massachusetts 23 trials
Florida 19 trials
Ohio 15 trials
New Jersey 13 trials
North Carolina 13 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Follicular Lymphoma page

90 registered trials, 49 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Follicular Lymphoma condition card totals 90 registered trials; most-linked intervention Cyclophosphamide; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.