Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Fatigue: early-phase trial registry
33 of 110 indexed Fatigue trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #116 of 28,707 conditions by registered trial count.
110 US clinical trials · 33 currently recruiting · #116 of 28,707 conditions by registered trial count
Fatigue: 110 US clinical trials tracked, 33 recruiting.
Fatigue is the subject of 110 registered US clinical trials on ClinicalTrials.gov, 33 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 8 of these trials.
Enrollment posture brief
Registry condition fatigue
OPEN 33 | RECR 30% | LATE 9 | EARLY 21 | RANK #116 | SPON 8
Volume-matched condition peers
Nearest open-share peer: Adrenocortical Carcinoma (30% recruiting · 10 trials)
Fatigue lists 33 open slots (30% of 110 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Fatigue on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Fatigue is recruiting below its size-band peers.
33 of 110 indexed trials (30%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Fatigue trials is spread across many organizations.
M.D. Anderson Cancer Center accounts for 8 of 110 trials (7.3%). 74 distinct sponsors appear on at least one study for this condition label.
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Most Fatigue trials plan to enrol fewer than 100 people.
Median target enrolment is 64 among the 110 trials that report a genuine target (sentinel values excluded). 70 of those (63.6%) plan for fewer than 100 participants.
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Fatigue research is mostly interventional.
102 interventional and 8 observational studies make up this index (92.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
110 total, page 3 of 3
Self-Management of Cancer-Related Fatigue by Adolescents
Seattle Children's Hospital
NCT00862186
Post-stroke Fatigue, Inflammation, tDCS
Medical University of South Carolina
NCT05330988
Aspirin as a Pre-Treatment for Exercise in Multiple Sclerosis
Columbia University
NCT03051646
Optimizing Sleep/Wake Related Cognitive Efficacy
Mayo Clinic
NCT02412410
A Proof-of-Concept Trial on the Effect of Ketamine on Fatigue
National Institute of Nursing Research (NINR)
NCT04141696
Virtual Reality at End-of-life
State University of New York at Buffalo
NCT06149429
Microbreaks in the OR to Mitigate High Physical and Mental Demands
Mayo Clinic
NCT02565394
Cognitive Behavioral Therapy and Light Therapy
University of Pennsylvania
NCT05337943
Programs to Support You During Chemotherapy (Pro-You)
Vanderbilt-Ingram Cancer Center
NCT02148406
Transcranial Direct Current Stimulation (tDCS) to Improve Fatigue and Cognitive Function
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03487601
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 9 |
| Phase 2 | 12 |
| Phase 3 | 7 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Fatigue records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Fatigue trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Fatigue page
110 registered trials, 33 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 33 Fatigue trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- M.D. Anderson Cancer Center sponsors the most Fatigue trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Fatigue condition card totals 110 registered trials; most-linked intervention questionnaire administration; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.