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ClinicalTrials.gov 10 recruiting now official registry

Executive Dysfunction clinical trials

Every US clinical trial registered for Executive Dysfunction — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

18 US clinical trials · 10 currently recruiting

The research picture

Executive Dysfunction has 18 registered US clinical trials, 10 of them open to new participants right now — about 56% of the total.

10
recruiting participants now
56%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: St. Jude Children's Research Hospital

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 3 372 participants

Goal-Directed Sedation in Mechanically Ventilated Infants and Children

Vanderbilt University Medical Center

NCT04801589

RECRUITING NA 310 participants

Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy

Children's Hospital Medical Center, Cincinnati

NCT06608966

RECRUITING NA 240 participants

HOPS Study: A Conceptual Replication

Children's Hospital of Philadelphia

NCT04465708

RECRUITING NA 144 participants

Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

Hebrew SeniorLife

NCT05661084

RECRUITING NA 100 participants

Randomized Controlled Trial of a Behavioral Training App

New York University

NCT06447909

RECRUITING Phase 1 72 participants

Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease

St. Jude Children's Research Hospital

NCT07226219

RECRUITING Phase 2 70 participants

A Digital Intervention for Post-Stroke Depression and Executive Dysfunction

Weill Medical College of Cornell University

NCT05507138

RECRUITING NA 30 participants

Causal Role of the Aperiodic Signal for Working Memory

Florida State University

NCT06126809

RECRUITING NA 24 participants

Transcranial Direct Current Stimulation in Children With Autism

New York State Institute for Basic Research

NCT07092280

RECRUITING NA 20 participants

Engage for Late-Life Depression and Comorbid Executive Dysfunction

University of Nevada, Las Vegas

NCT05356611

ACTIVE NOT RECRUITING 600 participants

Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)

David Brunk, PA-C, MMS

NCT04033510

ACTIVE NOT RECRUITING NA 64 participants

Intervention-Induced Plasticity of Flexibility and Learning Mechanisms in ASD

Children's National Research Institute

NCT05131659

ACTIVE NOT RECRUITING NA 36 participants

Transcranial Direct Current Stimulation of the Temporal Cortex in Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)

St. Jude Children's Research Hospital

NCT04105530

COMPLETED NA 137 participants

Online Emotion Regulation Group Intervention

Icahn School of Medicine at Mount Sinai

NCT03479606

COMPLETED NA 75 participants

Adaptation and Implementation of an ASD Executive Functioning Intervention in Children's Mental Health Services

San Diego State University

NCT04295512

COMPLETED NA 30 participants

High-Speed Yoga and Executive Function

University of Miami

NCT04215900

COMPLETED NA 17 participants

Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women

University of Colorado, Denver

NCT02122198

COMPLETED NA 8 participants

Case Studies: Promoting Strategy Use in Functional Activities

Weill Medical College of Cornell University

NCT04363645

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Executive Dysfunction Trial Landscape

ClinicalTrials.gov lists 18 US studies indexed under Executive Dysfunction, and 10 of those are currently open to recruitment — roughly 56% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Executive Dysfunction shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Executive Dysfunction is led by St. Jude Children's Research Hospital with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 18 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Executive Dysfunction?

PlainTrial tracks 18 US clinical trials for Executive Dysfunction, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Executive Dysfunction?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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