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NCT05339139 · ClinicalTrials.gov registry record · Phase 3
SAfety of Regional Citrate Anticoagulation (SARCA Study)
A Phase 3 study of Acute Kidney Injury and ESRD, sponsored by Fresenius Medical Care North America.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 50
- Enrollment target
- 10
- Study locations
NCT05339139: Recruiting Phase 3 study of Acute Kidney Injury and ESRD, sponsored by Fresenius Medical Care North America.
NCT05339139 is a Phase 3 study of Acute Kidney Injury and ESRD that is actively recruiting participants, run by Fresenius Medical Care North America. The registered enrollment target is 50 participants, below the 2,330-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (98% lower). The trial reports 10 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05339139, a Phase 3 study of Acute Kidney Injury and ESRD, is actively recruiting participants, sponsored by Fresenius Medical Care North America.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 50 participants
- Enrollment target
- 10
- Study locations
Study Summary
This is an Open-label, Prospective, Multicenter Study to Assess the SAfety of Regional Citrate Anticoagulation Delivered by the multiFiltratePRO system in Adult Patients Requiring Continuous Renal Replacement Therapy (SARCA Study).
Primary Outcome
Defined as a symptomatic episode of delirium, coma, nausea, vomiting, constipation, muscle weakness, hypertension, bradycardia, deemed attributable to hypercalcemia with a confirmed systemic ionized calcium \> 1.5mmol/L.
Conditions Studied
Interventions
- COMBINATION_PRODUCT Dialysis
Study Locations (10)
Arkansas
- John L. McClellan Memorial Veterans' Hospital - Little Rock
- University of Arkansas for Medical Sciences (UAMS) - Little Rock
Michigan
- University of Michigan - Ann Arbor
- Henry Ford Hospital - Detroit
Florida
- Advent Health Orlando - Orlando
Massachusetts
- UMass Memorial Medical Center - Worcester
Minnesota
- Mayo Clinic - Rochester
Mississippi
- University of Mississippi Medical Center - Jackson
Missouri
- Washington University - Hospital - St Louis
Utah
- Intermountain Health - Murray
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-10-17 |
| Est. Completion | 2025-07-31 |
| Phase | Phase 3 |
What NCT05339139 shows while recruiting
NCT05339139 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 2,330-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Acute Kidney Injury appearing as the primary indexed condition, and to 1 intervention - of which Dialysis is the first listed.
NCT05339139 lists 10 locations in 8 states (Arkansas, Michigan, Florida).
Frequently Asked Questions
What is clinical trial NCT05339139 about?
NCT05339139 is a clinical study titled "SAfety of Regional Citrate Anticoagulation (SARCA Study)". This is an Open-label, Prospective, Multicenter Study to Assess the SAfety of Regional Citrate Anticoagulation Delivered by the multiFiltratePRO system in Adult Patients Requiring Continuous Renal Replacement Therapy (SARCA Study).
What is the current status of trial NCT05339139?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 50 participants. The study started on 2023-10-17. Estimated completion is 2025-07-31.
What conditions does trial NCT05339139 study?
This clinical trial studies the following conditions: Acute Kidney Injury, ESRD.
What interventions are being tested in trial NCT05339139?
The interventions under investigation include: Dialysis (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT05339139?
This trial is sponsored by Fresenius Medical Care North America, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05339139 being conducted?
This trial has 10 study locations across Arkansas, Florida, Massachusetts, Michigan, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Kidney Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05339139's enrollment target sits among peer trials
50 56th of 74 higher than 17 of 74 other Acute Kidney Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Kidney Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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