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ClinicalTrials.gov 5 recruiting now full pipeline small index

Eosinophilic Esophagitis (EoE): full-pipeline trial registry

5 of 11 indexed Eosinophilic Esophagitis (EoE) trials are currently recruiting.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 5 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Eosinophilic Esophagitis (EoE): 11 US clinical trials tracked, 5 recruiting.

Eosinophilic Esophagitis (EoE) is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Regeneron Pharmaceuticals, running 3 of these trials.

Enrollment posture brief

Registry condition eosinophilic-esophagitis-eoe

OPEN 5 | RECR 45% | LATE 4 | EARLY 3 | RANK #1577 | SPON 3

Nearest open-share peer: Advanced Breast Carcinoma (45% recruiting · 11 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Eosinophilic Esophagitis (th…45%Acquired Brain Injury36.4%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis (EoE) lists 5 open slots (45% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Eosinophilic Esophagitis (EoE) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Eosinophilic Esophagitis (EoE) recruits in line with its size-band peers.

    5 of 11 indexed trials (45.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Eosinophilic Esophagitis (EoE) research.

    Regeneron Pharmaceuticals accounts for 3 of 11 trials (27.3%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Typical Eosinophilic Esophagitis (EoE) enrolment sits around 93 participants.

    Median target enrolment is 93 among the 11 trials that report a genuine target (sentinel values excluded). 6 of those (54.5%) plan for fewer than 100 participants.

  4. Eosinophilic Esophagitis (EoE) splits between interventional and observational designs.

    7 interventional and 4 observational studies make up this index (63.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 23Phase 33Phase 41

Open and recent trials

11 total, page 1 of 1

RECRUITING 350 participants

A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

Regeneron Pharmaceuticals

NCT06693531

RECRUITING 75 participants

Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy

Children's Hospital of Philadelphia

NCT06389994

RECRUITING 30 participants

Surface EMG Testing on Swallowing in EoE Patients

Mayo Clinic

NCT07156357

RECRUITING Phase 4 30 participants

Effect of Dupilumab on the Muscle Function of the Esophagus (food Pipe) in Participants with Eosinophilic Esophagitis (EoE)

University of California, San Diego

NCT06665971

RECRUITING Phase 3 20 participants

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

Regeneron Pharmaceuticals

NCT07112378

ACTIVE NOT RECRUITING Phase 2 184 participants

A Study to Investigate the Efficacy and Safety of NSI-8226 in Adults With Eosinophilic Esophagitis

Uniquity One (UNI)

NCT06598462

COMPLETED Phase 3 219 participants

An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE)

Shire

NCT02736409

COMPLETED Phase 2 129 participants

SOFEED: Six Food vs. One Food Eosinophilic Esophagitis Diet Study

Children's Hospital Medical Center, Cincinnati

NCT02778867

COMPLETED Phase 3 102 participants

Study to Investigate the Efficacy and Safety of Dupilumab in Pediatric Patients With Active Eosinophilic Esophagitis (EoE)

Regeneron Pharmaceuticals

NCT04394351

COMPLETED Phase 2 93 participants

OBS in Adolescent and Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an Open Label Extension

Shire

NCT01642212

COMPLETED 31 participants

Eating With Eosinophilic Esophagitis (EoE)

Mayo Clinic

NCT03581838

Phase Distribution

PhaseTrial count
Phase 2 3
Phase 3 3
Phase 4 1

Named interventions

Most-linked intervention names on Eosinophilic Esophagitis (EoE) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

dupilumab Drug
2 trials
Placebo Drug
2 trials
Fluticasone Propionate, 880 mcg twice daily (after 6FED failure) Drug
1 trials
6 Food Elimination Diet (after 1FED failure) Other
1 trials
6 Food Elimination Diet Therapy Other
1 trials
1 Food Elimination Diet Therapy Other
1 trials
Oral Budesonide Suspension (MB-9) Drug
1 trials
Observed eating session Behavioral
1 trials

US sites by state

Facility locations filed on Eosinophilic Esophagitis (EoE) trials. A trial with sites in several states counts in each.

California 7 trials
Illinois 6 trials
Colorado 6 trials
Arizona 6 trials
Georgia 5 trials
North Carolina 4 trials
Minnesota 4 trials
Massachusetts 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Eosinophilic Esophagitis (EoE) page

11 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Eosinophilic Esophagitis (EoE) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Regeneron Pharmaceuticals sponsors the most Eosinophilic Esophagitis (EoE) trials on record, review their full trial history before evaluating a specific study. See Regeneron Pharmaceuticals's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Eosinophilic Esophagitis (EoE) condition card totals 11 registered trials; most-linked intervention dupilumab; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.