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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Advanced Breast Carcinoma: early-phase trial registry

5 of 11 indexed Advanced Breast Carcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 5 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Advanced Breast Carcinoma: 11 US clinical trials tracked, 5 recruiting.

Advanced Breast Carcinoma is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition advanced-breast-carcinoma

OPEN 5 | RECR 45% | LATE 0 | EARLY 9 | RANK #1577 | SPON 3

Nearest open-share peer: Anger (45% recruiting · 11 trials)

Acute Pancreatitis81.8%Acute Stroke45.5%Advanced Breast Carcinom (th…45%Acquired Brain Injury36.4%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Advanced Breast Carcinoma

Advanced Breast Carcinoma lists 5 open slots (45% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Advanced Breast Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Advanced Breast Carcinoma recruits in line with its size-band peers.

    5 of 11 indexed trials (45.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Advanced Breast Carcinoma research.

    M.D. Anderson Cancer Center accounts for 3 of 11 trials (27.3%). 5 distinct sponsors appear on at least one study for this condition label.

  3. Most Advanced Breast Carcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 11 trials that report a genuine target (sentinel values excluded). 10 of those (90.9%) plan for fewer than 100 participants.

  4. Advanced Breast Carcinoma research is mostly interventional.

    9 interventional and 2 observational studies make up this index (81.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 24

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 2 220 participants

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

Mayo Clinic

NCT05969860

RECRUITING Phase 2 60 participants

Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer

M.D. Anderson Cancer Center

NCT04090567

RECRUITING Phase 1 51 participants

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

National Cancer Institute (NCI)

NCT04704661

RECRUITING 50 participants

Living Well With Advanced Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT07227038

RECRUITING Phase 1 43 participants

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

M.D. Anderson Cancer Center

NCT05092373

ACTIVE NOT RECRUITING Phase 1 74 participants

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

National Cancer Institute (NCI)

NCT04491942

ACTIVE NOT RECRUITING 68 participants

Genetic Analysis in Blood and Tumor Samples From Patients With Advanced or Metastatic Estrogen Receptor Positive and HER2 Negative Breast Cancer Receiving Palbociclib and Endocrine Therapy

Mayo Clinic

NCT03281902

ACTIVE NOT RECRUITING Phase 2 30 participants

A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

OHSU Knight Cancer Institute

NCT06630325

ACTIVE NOT RECRUITING Phase 1 23 participants

PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery

National Cancer Institute (NCI)

NCT03218826

ACTIVE NOT RECRUITING Phase 2 17 participants

TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer

Mayo Clinic

NCT03179904

COMPLETED Phase 1 18 participants

Alpelisib and Enzalutamide in Treating Patients With Androgen Receptor and PTEN Positive Metastatic Breast Cancer

M.D. Anderson Cancer Center

NCT03207529

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 4

Named interventions

Most-linked intervention names on Advanced Breast Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Ceralasertib Drug
2 trials
Echocardiography Procedure
2 trials
Laboratory Biomarker Analysis Other
2 trials
Biopsy Procedure
2 trials
Biospecimen Collection Procedure
2 trials
PI3Kbeta Inhibitor AZD8186 Drug
1 trials
Denifanstat Drug
1 trials
Elimusertib Drug
1 trials

US sites by state

Facility locations filed on Advanced Breast Carcinoma trials. A trial with sites in several states counts in each.

Texas 5 trials
Florida 4 trials
Ohio 3 trials
New York 3 trials
Maryland 3 trials
Pennsylvania 2 trials
Minnesota 2 trials
California 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Advanced Breast Carcinoma page

11 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Advanced Breast Carcinoma condition card totals 11 registered trials; most-linked intervention Ceralasertib; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.