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ClinicalTrials.gov 12 recruiting now official registry

Endometrial Carcinoma clinical trials

Every US clinical trial registered for Endometrial Carcinoma — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

28 US clinical trials · 12 currently recruiting

The research picture

Endometrial Carcinoma has 28 registered US clinical trials, 12 of them open to new participants right now — about 43% of the total.

12
recruiting participants now
43%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
6
top sponsor: Mayo Clinic

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 3 360 participants

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

National Cancer Institute (NCI)

NCT05256225

RECRUITING 300 participants

Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia With an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients With Post-Menopausal Bleeding

Mayo Clinic

NCT06365905

RECRUITING Phase 1 147 participants

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Children's Oncology Group

NCT04851119

RECRUITING NA 120 participants

Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer

Mayo Clinic

NCT04567771

RECRUITING NA 120 participants

An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study

Roswell Park Cancer Institute

NCT06855706

RECRUITING Phase 1 113 participants

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

Fate Therapeutics

NCT07216105

RECRUITING 100 participants

Molecular and ctDNA Characterization of High-Risk Endometrial Cancer

Mayo Clinic

NCT07062016

RECRUITING 60 participants

Screening and Staging of Benign vs Malignant Pelvic Abnormalities

Mayo Clinic

NCT07407959

RECRUITING Phase 1 60 participants

Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer

National Cancer Institute (NCI)

NCT06253494

RECRUITING NA 30 participants

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

Dana-Farber Cancer Institute

NCT04839614

RECRUITING Early Phase 1 28 participants

A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer

Memorial Sloan Kettering Cancer Center

NCT05691010

RECRUITING Phase 2 27 participants

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

Mayo Clinic

NCT07285044

ACTIVE NOT RECRUITING Phase 2 6,452 participants

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

National Cancer Institute (NCI)

NCT02465060

ACTIVE NOT RECRUITING Phase 1 1,410 participants

Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)

Klus Pharma

NCT04152499

ACTIVE NOT RECRUITING 310 participants

Pelvic Floor Dysfunction and Quality of Life in Uterine Cancer Survivors

M.D. Anderson Cancer Center

NCT04634617

ACTIVE NOT RECRUITING 191 participants

Targeting Inflammation for Endometrial Cancer Prevention

Mayo Clinic

NCT05407025

ACTIVE NOT RECRUITING Phase 1 94 participants

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

National Cancer Institute (NCI)

NCT01366144

ACTIVE NOT RECRUITING 89 participants

Changes in Pelvic Health, Sexual Function, and Quality of Life in Women With Pelvic Cancer Undergoing Radiation Therapy

Ohio State University Comprehensive Cancer Center

NCT04713618

ACTIVE NOT RECRUITING 79 participants

Longitudinal Evaluation of Women Undergoing Pelvic Surgery for the Treatment of Gynecologic Cancer

M.D. Anderson Cancer Center

NCT00791635

ACTIVE NOT RECRUITING Phase 2 51 participants

Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

Northwestern University

NCT04576104

ACTIVE NOT RECRUITING Phase 2 50 participants

A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma

Yale University

NCT04251416

ACTIVE NOT RECRUITING Phase 2 44 participants

Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy

City of Hope Medical Center

NCT03671811

ACTIVE NOT RECRUITING NA 22 participants

Hypofractionated Radiotherapy for the Treatment of Cervical or Endometrial Cancer

University of Utah

NCT05139368

COMPLETED Phase 1 150 participants

A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Xencor

NCT03517488

COMPLETED Phase 2 47 participants

Health and Recovery Program in Increasing Physical Activity Level in Stage IA-IIIA Endometrial Cancer Survivors

Stanford University

NCT03367923

COMPLETED 40 participants

Dosimetric Analysis of Vaginal Cuff Brachytherapy in Endometrial Carcinoma

Dana-Farber Cancer Institute

NCT00165126

COMPLETED Phase 2 35 participants

A Study of Nivolumab in Selected Uterine Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT03241745

COMPLETED Phase 2 22 participants

Trial of Maintenance With Niraparib- Uterine Serous Carcinoma

Northwell Health

NCT04080284

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 8
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Endometrial Carcinoma Trial Landscape

ClinicalTrials.gov lists 28 US studies indexed under Endometrial Carcinoma, and 12 of those are currently open to recruitment — roughly 43% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Endometrial Carcinoma shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Endometrial Carcinoma is led by Mayo Clinic with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 28 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Endometrial Carcinoma?

PlainTrial tracks 28 US clinical trials for Endometrial Carcinoma, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Endometrial Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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