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NCT03671811 · ClinicalTrials.gov registry record · Phase 2

Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy

A Phase 2 study of Endometrial Carcinoma and Atypical Endometrial Hyperplasia, sponsored by City of Hope Medical Center.

Active
Registry status
Phase 2
Development phase
44
Enrollment target
1
Study location

NCT03671811 is a Phase 2 study of Endometrial Carcinoma and Atypical Endometrial Hyperplasia that is active but no longer recruiting, run by City of Hope Medical Center. The registered enrollment target is 44 participants, below the 389-participant average among 27 other Endometrial Carcinoma trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03671811, a Phase 2 study of Endometrial Carcinoma and Atypical Endometrial Hyperplasia, is active but no longer recruiting, sponsored by City of Hope Medical Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
44 participants
Enrollment target
1
Study location

Study Summary

This phase II trial studies how well megestrol acetate with or without pterostilbene works in treating patients with endometrial cancer undergoing hysterectomy. Drugs used in chemotherapy, such as megestrol acetate, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Pterostilbene is an antioxidant found in blueberries or grapes, and it has been shown to be effective in killing tumor cells and reducing cancer burden. It is not yet known whether giving megestrol acetate with or without pterostilbene may work better in treating patients with endometrial cancer.

Interventions

  • DRUG Megestrol Acetate
  • BIOLOGICAL Pterostilbene

Study Locations (1)

California

  • City of Hope Medical Center - Duarte

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2019-01-21
Est. Completion 2026-03-30
Phase Phase 2

Sponsor

City of Hope Medical Center

582 total trials

What the Registry Record Tells You About NCT03671811

The ClinicalTrials.gov registry entry for NCT03671811 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 389-participant average among 27 other Endometrial Carcinoma trials with a reported enrollment target (89% lower). The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Endometrial Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Megestrol Acetate is the first listed.

NCT03671811 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03671811 about?

NCT03671811 is a clinical study titled "Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy". This phase II trial studies how well megestrol acetate with or without pterostilbene works in treating patients with endometrial cancer undergoing hysterectomy. Drugs used in chemotherapy, such as megestrol acetate, work in different ways to stop the growth of tumor cells, either by killing the cell...

What is the current status of trial NCT03671811?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2019-01-21. Estimated completion is 2026-03-30.

What conditions does trial NCT03671811 study?

This clinical trial studies the following conditions: Endometrial Carcinoma, Atypical Endometrial Hyperplasia.

What interventions are being tested in trial NCT03671811?

The interventions under investigation include: Megestrol Acetate (DRUG), Pterostilbene (BIOLOGICAL).

Who is sponsoring clinical trial NCT03671811?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03671811 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.