Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
E-cigarette Use: early-phase trial registry
9 of 13 indexed E-cigarette Use trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,315 of 28,707 conditions by registered trial count.
13 US clinical trials · 9 currently recruiting · #1,315 of 28,707 conditions by registered trial count
E-cigarette Use: 13 US clinical trials tracked, 9 recruiting.
E-cigarette Use is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 2 of these trials.
Enrollment posture brief
Registry condition e-cigarette-use
OPEN 9 | RECR 69% | LATE 0 | EARLY 4 | RANK #1315 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Ankle Fractures (69% recruiting · 13 trials)
E-cigarette Use lists 9 open slots (69% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for E-cigarette Use on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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E-cigarette Use is recruiting above its size-band peers.
9 of 13 indexed trials (69.2%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates E-cigarette Use research.
Yale University accounts for 2 of 13 trials (15.4%). 12 distinct sponsors appear on at least one study for this condition label.
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Typical E-cigarette Use enrolment sits around 80 participants.
Median target enrolment is 80 among the 13 trials that report a genuine target (sentinel values excluded). 7 of those (53.8%) plan for fewer than 100 participants.
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E-cigarette Use research is mostly interventional.
13 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
13 total, page 1 of 1
A Trial of Varenicline for E-cigarette Cessation
Yale University
NCT07040566
Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
Abramson Cancer Center at Penn Medicine
NCT06372899
Evaluation of the Electronic Cigarette Withdrawal Syndrome
Johns Hopkins University
NCT06066996
An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults
University of Southern California
NCT06129123
Sex Differences in the Vascular Effects of E-cigarette Use
Anna Stanhewicz, PhD
NCT06159608
Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing
Virginia Polytechnic Institute and State University
NCT07161050
Vape-Free Text-Messaging: Pilot Study
Jovan Gwon, PhD, RN, FIAAN
NCT05906082
Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use
Yale University
NCT06027840
Adapting an Intervention for Vaping in Young Veterans
Veterans Medical Research Foundation
NCT06196489
Tobacco Product Susceptibility and Substitutability by Rurality and Alcohol Use
Mark J Rzeszutek, PhD
NCT07010601
PACE Vape Messaging Study
University of Vermont
NCT04450537
Vaper to Vaper: A Multimodal Mobile Peer Driven Intervention to Support Adolescents in Quitting Vaping
University of Massachusetts, Worcester
NCT05140915
Acute Effects of TCIG vs ECIG in PLWH
University of California, Los Angeles
NCT04568395
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on E-cigarette Use records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on E-cigarette Use trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this E-cigarette Use page
13 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 9 E-cigarette Use trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Yale University sponsors the most E-cigarette Use trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This E-cigarette Use condition card totals 13 registered trials; most-linked intervention sham control; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.