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ClinicalTrials.gov 9 recruiting now early-phase tilt small index

Ankle Fractures: early-phase trial registry

9 of 13 indexed Ankle Fractures trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 9 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Ankle Fractures: 13 US clinical trials tracked, 9 recruiting.

Ankle Fractures is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is J L Marsh, running 1 of these trials.

Enrollment posture brief

Registry condition ankle-fractures

OPEN 9 | RECR 69% | LATE 1 | EARLY 2 | RANK #1315 | SPON 1

Nearest open-share peer: Aortic Dissection (69% recruiting · 13 trials)

Ankle Fractures (this)69%ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%
Open-enrollment share among volume-matched conditions near Ankle Fractures

Ankle Fractures lists 9 open slots (69% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Ankle Fractures on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Ankle Fractures is recruiting above its size-band peers.

    9 of 13 indexed trials (69.2%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Ankle Fractures trials is spread across many organizations.

    J L Marsh accounts for 1 of 13 trials (7.7%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Most Ankle Fractures trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 13 trials that report a genuine target (sentinel values excluded). 8 of those (61.5%) plan for fewer than 100 participants.

  4. Ankle Fractures research is mostly interventional.

    12 interventional and 1 observational studies make up this index (92.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 41

Open and recent trials

13 total, page 1 of 1

RECRUITING NA 390 participants

Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery

Oregon Health and Science University

NCT05445960

RECRUITING NA 140 participants

Comparing Clinical Outcomes of Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries

University of California, San Diego

NCT05729542

RECRUITING Phase 4 70 participants

Randomized Controlled Trial for Ankle Fracture Pain Control

Lahey Clinic

NCT03696199

RECRUITING NA 60 participants

Efficacy and Clinical Feasibility of the Ankle Muscle Power (AMP) Program for Return to Duty After an Ankle Fracture

Brian W. Noehren

NCT07173088

RECRUITING NA 56 participants

Fibulink Syndesmosis Repair System With Early Full-Weight Bearing

Maimonides Medical Center

NCT06085586

RECRUITING NA 30 participants

Simplified Post Op Rehabilitation for Ankle and Pilon Fractures

University of Virginia

NCT05280639

RECRUITING NA 25 participants

Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures

Kyle Schweser MD

NCT03966027

RECRUITING NA 20 participants

Neuromuscular Electrical Stimulation in Foot and Ankle Surgery

NYU Langone Health

NCT06370325

RECRUITING NA 20 participants

An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA

J L Marsh

NCT03809520

ACTIVE NOT RECRUITING 1,500 participants

Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®

AO Innovation Translation Center

NCT04113044

ACTIVE NOT RECRUITING Early Phase 1 200 participants

Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures

University of Utah

NCT05019638

COMPLETED Early Phase 1 500 participants

Postoperative Aspirin and Ankle Fracture Healing

University of Alabama at Birmingham

NCT03765619

COMPLETED NA 30 participants

Telerehabilitation Following Ankle Fractures

Johns Hopkins University

NCT04235907

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 4 1

Named interventions

Most-linked intervention names on Ankle Fractures records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Standard rehabilitation Other
1 trials
Telerehabilitation Other
1 trials
Local multimodal analgesia group Drug
1 trials
Regional anesthesia group Drug
1 trials
All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics. Other
1 trials
pedCAT Radiation
1 trials
Long-Acting Local Anesthesia Drug
1 trials
Postoperative Protocol (Delayed Weight Bearing) Other
1 trials

US sites by state

Facility locations filed on Ankle Fractures trials. A trial with sites in several states counts in each.

New York 2 trials
Massachusetts 2 trials
California 2 trials
Virginia 1 trials
Utah 1 trials
Texas 1 trials
Oregon 1 trials
Missouri 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Ankle Fractures page

13 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 9 Ankle Fractures trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • J L Marsh sponsors the most Ankle Fractures trials on record, review their full trial history before evaluating a specific study. See J L Marsh's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ankle Fractures condition card totals 13 registered trials; most-linked intervention Standard rehabilitation; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.