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ClinicalTrials.gov 9 recruiting now official registry

Ankle Fractures clinical trials

9 of 13 indexed Ankle Fractures trials are currently recruiting.

13 US clinical trials · 9 currently recruiting

Ankle Fractures is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is J L Marsh, running 1 of these trials.

The research picture

Ankle Fractures has 13 registered US clinical trials, 9 of them open to new participants right now, about 69% of the total.

9
recruiting participants now
69%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
1
top sponsor: J L Marsh
Phase 12Phase 41

Active & Recent Trials

13 total, page 1 of 1

RECRUITING NA 390 participants

Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery

Oregon Health and Science University

NCT05445960

RECRUITING NA 140 participants

Comparing Clinical Outcomes of Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries

University of California, San Diego

NCT05729542

RECRUITING Phase 4 70 participants

Randomized Controlled Trial for Ankle Fracture Pain Control

Lahey Clinic

NCT03696199

RECRUITING NA 60 participants

Efficacy and Clinical Feasibility of the Ankle Muscle Power (AMP) Program for Return to Duty After an Ankle Fracture

Brian W. Noehren

NCT07173088

RECRUITING NA 56 participants

Fibulink Syndesmosis Repair System With Early Full-Weight Bearing

Maimonides Medical Center

NCT06085586

RECRUITING NA 30 participants

Simplified Post Op Rehabilitation for Ankle and Pilon Fractures

University of Virginia

NCT05280639

RECRUITING NA 25 participants

Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures

Kyle Schweser MD

NCT03966027

RECRUITING NA 20 participants

Neuromuscular Electrical Stimulation in Foot and Ankle Surgery

NYU Langone Health

NCT06370325

RECRUITING NA 20 participants

An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA

J L Marsh

NCT03809520

ACTIVE NOT RECRUITING 1,500 participants

Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®

AO Innovation Translation Center

NCT04113044

ACTIVE NOT RECRUITING Early Phase 1 200 participants

Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures

University of Utah

NCT05019638

COMPLETED Early Phase 1 500 participants

Postoperative Aspirin and Ankle Fracture Healing

University of Alabama at Birmingham

NCT03765619

COMPLETED NA 30 participants

Telerehabilitation Following Ankle Fractures

Johns Hopkins University

NCT04235907

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Ankle Fractures Trial Landscape

13 indexed Ankle Fractures studies · 9 recruiting (69%).

Phase mix: 1 late (III/IV) vs 2 early (I/II).

Top sponsor: J L Marsh (1 trial), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Ankle Fractures?

PlainTrial tracks 13 US clinical trials for Ankle Fractures, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Ankle Fractures?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.