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NCT05384262 · ClinicalTrials.gov registry record · Phase 1

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

A Phase 1 study of Dyslipidemia, sponsored by AstraZeneca.

Completed
Registry status
Phase 1
Development phase
183
Enrollment target
3
Study locations

NCT05384262 is a Phase 1 study of Dyslipidemia that has completed, run by AstraZeneca. The registered enrollment target is 183 participants, below the 358-participant average among 40 other Dyslipidemia trials with a reported enrollment target (49% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT05384262, a Phase 1 study of Dyslipidemia, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 1
Development phase
183 participants
Enrollment target
3
Study locations

Study Summary

This study will assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of AZD0780 following single and multiple dose administration to healthy subjects with or without elevated Low-Density Lipoprotein-Cholesterol (LDL-C) levels. This study will consist of two parts (Parts A and B). 56 subjects have been planned for Part A and 141 subjects for Part B. Additional subjects may be included for the optional cohorts depending upon emerging data.

Conditions Studied

Dyslipidemia

Interventions

  • DRUG Placebo
  • DRUG AZD0780

Study Locations (3)

California

  • Research Site - Glendale

Maryland

  • Research Site - Brooklyn

Other

  • Research Site - Harrow

Trial Details

FieldValue
Enrollment Target 183 participants
Start Date 2022-05-18
Est. Completion 2024-06-14
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

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What the Registry Record Tells You About NCT05384262

The ClinicalTrials.gov registry entry for NCT05384262 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 183 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 358-participant average among 40 other Dyslipidemia trials with a reported enrollment target (49% lower). The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Dyslipidemia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05384262 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Maryland, Other.

Frequently Asked Questions

What is clinical trial NCT05384262 about?

NCT05384262 is a clinical study titled "A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects". This study will assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of AZD0780 following single and multiple dose administration to healthy subjects with or without elevated Low-Density Lipoprotein-Cholesterol (LDL-C) levels. This study will consist of two parts (Parts...

What is the current status of trial NCT05384262?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 183 participants. The study started on 2022-05-18. Estimated completion is 2024-06-14.

What conditions does trial NCT05384262 study?

This clinical trial studies the following conditions: Dyslipidemia.

What interventions are being tested in trial NCT05384262?

The interventions under investigation include: Placebo (DRUG), AZD0780 (DRUG).

Who is sponsoring clinical trial NCT05384262?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05384262 being conducted?

This trial has 3 study locations across California, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.