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Colon Cancer: early-phase trial registry
34 of 99 indexed Colon Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #140 of 28,707 conditions by registered trial count.
99 US clinical trials · 34 currently recruiting · #140 of 28,707 conditions by registered trial count
Colon Cancer: 99 US clinical trials tracked, 34 recruiting.
Colon Cancer is the subject of 99 registered US clinical trials on ClinicalTrials.gov, 34 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 37 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 6 of these trials.
Enrollment posture brief
Registry condition colon-cancer
OPEN 34 | RECR 34% | LATE 4 | EARLY 37 | RANK #140 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Stage IIIB Lung Cancer AJCC v8 (34% recruiting · 32 trials)
Colon Cancer lists 34 open slots (34% of 99 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Colon Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Colon Cancer is recruiting below its size-band peers.
34 of 99 indexed trials (34.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Colon Cancer trials is spread across many organizations.
National Cancer Institute (NCI) accounts for 6 of 99 trials (6.1%). 73 distinct sponsors appear on at least one study for this condition label.
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Typical Colon Cancer enrolment sits around 110 participants.
Median target enrolment is 110 among the 98 trials that report a genuine target (sentinel values excluded). 45 of those (45.9%) plan for fewer than 100 participants.
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Colon Cancer research is mostly interventional.
76 interventional and 23 observational studies make up this index (76.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
99 total, page 2 of 2
A Study of Imaging, Blood, and Tissue Samples to Guide Treatment of Colon Cancer and Related Liver Tumors
Memorial Sloan Kettering Cancer Center
NCT03432806
CEND-1 in Combination with Neoadjuvant FOLFIRINOX with or Without Panitumumab
Anup Kasi
NCT05121038
Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer
University of Colorado, Denver
NCT04963283
A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation
HUYABIO International
NCT05485974
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS
Immunophotonics
NCT05688280
Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer
M.D. Anderson Cancer Center
NCT05722327
Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer
City of Hope Medical Center
NCT02293954
Evaluating a Physical Activity Index for Assessment and Counseling for Breast and Colon Cancer Survivors
Wake Forest University Health Sciences
NCT06340503
A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
GlaxoSmithKline
NCT06710847
Oncology Episode Payment Model in Hawaii
University of Pennsylvania
NCT03523546
General Surgical Outcomes Quality Improvement Database (UH-SOCRATES)
University Hospitals Cleveland Medical Center
NCT00622557
Mailed FIT Outreach 2022
Abramson Cancer Center at Penn Medicine
NCT05341622
Study of Colorectal Cancer Screening Options
Kaiser Permanente
NCT05987709
Adherence to Colon Cancer Screening (ACCS)
Ohio State University Comprehensive Cancer Center
NCT02112747
Online Study of Colorectal Cancer and Prostate Cancer Screening Decision Making
University of North Carolina, Chapel Hill
NCT01558583
Patient Navigator Project
H. Lee Moffitt Cancer Center and Research Institute
NCT00375024
Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus Trisulfate Solution Using 2-Day Split-Dosing Regimen in Adults
Norgine
NCT02254486
Impact of a Novel Patient Educational Booklet on Colonoscopy Quality
VA Greater Los Angeles Healthcare System
NCT00975247
BLI850-302: BLI850 vs an Approved Active Control Bowel Preparation in Adult Subjects Undergoing Colonoscopy
Braintree Laboratories
NCT00756548
Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer
Wake Forest University Health Sciences
NCT01656044
Men Together Making a Difference: Health Promotion for Black Men
University of Pennsylvania
NCT02572414
Patient Activation Intervention in Improving Screening Rates for Colorectal Cancer
Ohio State University Comprehensive Cancer Center
NCT01801059
Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
Indiana University
NCT03462706
A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
Esperas Pharma
NCT02632448
Phase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal Cancer
Amgen
NCT00625651
FOcus on Reducing Dose-limiting Toxicities in Colon Cancer With Resistance Exercise Study
Kaiser Permanente
NCT03291951
Reducing VA No-Shows: Evaluation of Predictive Overbooking Applied to Colonoscopy
VA Office of Research and Development
NCT01639443
Prospective Randomized Controlled Trial Comparing Water and Air Colonoscopy in a Community Based Setting
University of California, Davis
NCT01729416
Understanding the Value of Community Vital Signs in Primary Care
Virginia Commonwealth University
NCT02512835
GI SPORE Colon Biosample Protocol
University of Michigan
NCT02243267
Safety of BKM120 Monotherapy in Advanced Solid Tumor Patients
Novartis Pharmaceuticals
NCT01068483
Screening for Gynecologic Cancers in Hereditary Nonpolyposis Colorectal Cancer (HNPCC) Patients
M.D. Anderson Cancer Center
NCT00508846
Latino Peers as Patient Navigators for Colon Cancer Screening
Icahn School of Medicine at Mount Sinai
NCT02226107
An Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy
Corewell Health West
NCT00467922
Imaging Study on Halcyon 4.0 System for Patients Receiving Radiation Therapy
Washington University School of Medicine
NCT05427214
CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer
David Bajor, MD
NCT02861300
Clinical Trial in Patients With Metastatic Colorectal Cancer
Mast Therapeutics
NCT00081627
Promoting Physical Activity After Colorectal Cancer
The Miriam Hospital
NCT00230646
Hybrid APC Assisted EMR for Large Colon Polyps
Milton S. Hershey Medical Center
NCT03390907
Sleep Coach: A Mobile App to Address Insomnia Symptoms Among Cancer Survivors
University of Michigan Rogel Cancer Center
NCT04827459
Feasibility of an Evidence-based Walking Program in Cancer Pts 60+ During Chemotherapy
UNC Lineberger Comprehensive Cancer Center
NCT01789983
Genetic Investigation of Solid Tumors Cohort
Scripps Translational Science Institute
NCT01005225
Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies
Novita Pharmaceuticals
NCT03199586
Where Culture Meets Genetics: Exploring Latinas Causal Attributions of Breast and Colon Cancer and Models of Disease Inheritance
National Human Genome Research Institute (NHGRI)
NCT02767986
Clinical and Translational Study of STA-9090
Memorial Sloan Kettering Cancer Center
NCT01111838
Cellular Immune Augmentation in Colon and Rectal Cancer
University of California, Irvine
NCT00257322
Multi-Targeted Recombinant Ad5 (CEA/MUC1/Brachyury) Based Immunotherapy Vaccine Regimen in People With Advanced Cancer
National Cancer Institute (NCI)
NCT03384316
Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers
National Cancer Institute (NCI)
NCT03801915
Heated Chemotherapy for Cancers That Have Spread to the Chest Cavity
St. Luke's-Roosevelt Hospital Center
NCT01163552
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 26 |
| Phase 2 | 11 |
| Phase 3 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Colon Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Colon Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Colon Cancer page
99 registered trials, 34 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 34 Colon Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Cancer Institute (NCI) sponsors the most Colon Cancer trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Colon Cancer condition card totals 99 registered trials; most-linked intervention Cemiplimab; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.