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ACTIVE NOT RECRUITING Phase 1

CEND-1 in Combination with Neoadjuvant FOLFIRINOX with or Without Panitumumab

NCT05121038 · View on ClinicalTrials.gov ↗

Study Summary

This is a phase IB/IIA trial to ensure the safety of Certepetide (LSTA1/CEND-1) in combination with with Folfirinox with or without Panitumumab for treatment of pancreatic, colon and appendiceal cancers

Interventions

  • DRUG Panitumumab
  • DRUG Folfirinox
  • DRUG CEND-1

Study Locations (3)

Kansas

  • The University of Kansas Cancer Center (KUCC) — Fairway
  • The University of Kansas Cancer Center, Westwood Campus — Kansas City

Missouri

  • The University of Kansas Medical Center — North Kansas City

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2021-10-20
Est. Completion 2026-09
Phase Phase 1

Sponsor

Anup Kasi

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05121038

The ClinicalTrials.gov registry entry for NCT05121038 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Anup Kasi, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Colon Cancer appearing as the primary indexed condition, and to 3 interventions — of which Panitumumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05121038 reports 3 study locations spanning 2 distinct geographic areas — top geographies include Kansas, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05121038 about?

NCT05121038 is a clinical study titled "CEND-1 in Combination with Neoadjuvant FOLFIRINOX with or Without Panitumumab". This is a phase IB/IIA trial to ensure the safety of Certepetide (LSTA1/CEND-1) in combination with with Folfirinox with or without Panitumumab for treatment of pancreatic, colon and appendiceal cancers

What is the current status of trial NCT05121038?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2021-10-20. Estimated completion is 2026-09.

What conditions does trial NCT05121038 study?

This clinical trial studies the following conditions: Colon Cancer, Pancreas Cancer, Digestive Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05121038?

The interventions under investigation include: Panitumumab (DRUG), Folfirinox (DRUG), CEND-1 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05121038?

This trial is sponsored by Anup Kasi, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05121038 being conducted?

This trial has 3 study locations across Kansas, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial