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NCT07209683 · ClinicalTrials.gov registry record · NA
The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults
A NA study of Cognition and Brain Aging, sponsored by University of Oklahoma.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT07209683 is a NA study of Cognition and Brain Aging that is actively recruiting participants, run by University of Oklahoma. The registered enrollment target is 30 participants, below the 171-participant average among 35 other Cognition trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07209683, a NA study of Cognition and Brain Aging, is actively recruiting participants, sponsored by University of Oklahoma.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this pilot clinical trial is to test whether transcranial photobiomodulation (tPBM), a non-invasive brain stimulation technique using near-infrared light, can improve brain blood flow regulation (neurovascular coupling) and cognitive function in older adults. The main questions it aims to answer are: * Does tPBM enhance neurovascular coupling responses during memory and finger tapping tasks? * Are these improvements linked to better cognitive performance and lower levels of brain inflammation and oxidative stress? Researchers will compare an active tPBM treatment arm to a sham treatment arm to see if tPBM leads to measurable improvements in brain activity and cognitive function compared to no active stimulation. Participants will: * Receive either active tPBM or sham stimulation sessions for 4 weeks, every other day using a portable intervention device. * Complete questionnaires and an iPAD-based cognitive testing protocol * Complete memory and motor tasks while their brain activity is measured using non-invasive techniques: simultaneous functional near-infrared spectroscopy (fNIRS) and electroencephalography (EEG), transcranial doppler (TCD) flowmetry. * Retinal vessel reactivity will be measured during flickering light stimulus using a special camera (dynamic vessel analysis, DVA). * Provide blood samples to test for biomarkers of inflammation, oxidative stress and brain cell damage.
Conditions Studied
Interventions
- DEVICE transcranial photobiomodulation
Study Locations (1)
Oklahoma
- University of Oklahoma Health Campus - Oklahoma City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-10-01 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07209683
The ClinicalTrials.gov registry entry for NCT07209683 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 171-participant average among 35 other Cognition trials with a reported enrollment target (82% lower). The listed sponsor is University of Oklahoma, which has 358 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Cognition appearing as the primary indexed condition, and to 1 intervention - of which transcranial photobiomodulation is the first listed.
NCT07209683 reports 1 study location spanning 1 distinct geographic area - top geographies include Oklahoma.
Frequently Asked Questions
What is clinical trial NCT07209683 about?
NCT07209683 is a clinical study titled "The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults". The goal of this pilot clinical trial is to test whether transcranial photobiomodulation (tPBM), a non-invasive brain stimulation technique using near-infrared light, can improve brain blood flow regulation (neurovascular coupling) and cognitive function in older adults. The main questions it aims ...
What is the current status of trial NCT07209683?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-10-01. Estimated completion is 2026-12-31.
What conditions does trial NCT07209683 study?
This clinical trial studies the following conditions: Cognition, Brain Aging, Neurovascular Control, Neurovascular Coupling Mechanism and Cognitive Function, Brain Activity.
What interventions are being tested in trial NCT07209683?
The interventions under investigation include: transcranial photobiomodulation (DEVICE).
Who is sponsoring clinical trial NCT07209683?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07209683 being conducted?
This trial has 1 study location across Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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