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NCT00218257 · ClinicalTrials.gov registry record · NA
Progesterone for the Treatment of Cocaine Dependence - 1
A NA study of Cocaine-Related Disorders and Cocaine Abuse, sponsored by University of Minnesota.
- Completed
- Registry status
- NA
- Development phase
- 96
- Enrollment target
- 1
- Study location
NCT00218257: Completed NA study of Cocaine-Related Disorders and Cocaine Abuse, sponsored by University of Minnesota.
NCT00218257 is a NA study of Cocaine-Related Disorders and Cocaine Abuse that has completed, run by University of Minnesota. The registered enrollment target is 96 participants, above the 59-participant average among 15 other Cocaine-Related Disorders trials with a reported enrollment target (63% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00218257, a NA study of Cocaine-Related Disorders and Cocaine Abuse, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- NA
- Development phase
- 96 participants
- Enrollment target
- 1
- Study location
Study Summary
Past research has demonstrated that cocaine dependent women experience less severe responses to cocaine during the luteal phase of the menstrual cycle, when estrogen and progesterone concentrations are high. The purpose of this study is to determine whether administered progesterone reduces subjective and physiological responses to cocaine in cocaine dependent individuals.
Primary Outcome
During 1 inpatient testing day, participants were given the opportunity to spend 5 earned tokens on either an active dose of cocaine or to keep the tokens for a $5 reward for each token. Decisions were solicited every 30 minutes. Outcome measure is reported as the percent of 5 decisions for which the participant chose to self-administer cocaine. 0% indicates that all 5 tokens were retained and traded for monetary reward. 100% indicates that the participant spent all 5 tokens on cocaine for self-
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Progesterone
Study Locations (1)
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2002-07 |
| Est. Completion | 2008-06-30 |
| Phase | NA |
What the finished NCT00218257 record still lists
NCT00218257 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 96 participants, a relatively small participant target, above the 59-participant average among 15 other Cocaine-Related Disorders trials with a reported enrollment target (63% higher).
The record links to 2 conditions, with Cocaine-Related Disorders appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00218257 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT00218257 about?
NCT00218257 is a clinical study titled "Progesterone for the Treatment of Cocaine Dependence - 1". Past research has demonstrated that cocaine dependent women experience less severe responses to cocaine during the luteal phase of the menstrual cycle, when estrogen and progesterone concentrations are high. The purpose of this study is to determine whether administered progesterone reduces subjecti...
What is the current status of trial NCT00218257?
This trial is currently completed. It is a NA study. The enrollment target is 96 participants. The study started on 2002-07. Estimated completion is 2008-06-30.
What conditions does trial NCT00218257 study?
This clinical trial studies the following conditions: Cocaine-Related Disorders, Cocaine Abuse.
What interventions are being tested in trial NCT00218257?
The interventions under investigation include: Placebo (OTHER), Progesterone (DRUG).
Who is sponsoring clinical trial NCT00218257?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00218257 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cocaine-Related Disorders
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00218257's enrollment target sits among peer trials
96 5th of 15 higher than 11 of 15 other Cocaine-Related Disorders trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cocaine-Related Disorders trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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