Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Chronic Migraine: later-stage trial registry
11 of 18 indexed Chronic Migraine trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #953 of 28,707 conditions by registered trial count.
18 US clinical trials · 11 currently recruiting · #953 of 28,707 conditions by registered trial count
Chronic Migraine: 18 US clinical trials tracked, 11 recruiting.
Chronic Migraine is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Ipsen, running 2 of these trials.
Enrollment posture brief
Registry condition chronic-migraine
OPEN 11 | RECR 61% | LATE 6 | EARLY 1 | RANK #953 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Breast Cancer Metastatic (61% recruiting · 18 trials)
Chronic Migraine lists 11 open slots (61% of 18 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Chronic Migraine on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Chronic Migraine is recruiting above its size-band peers.
11 of 18 indexed trials (61.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Chronic Migraine trials is spread across many organizations.
Ipsen accounts for 2 of 18 trials (11.1%). 15 distinct sponsors appear on at least one study for this condition label.
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Typical Chronic Migraine enrolment sits around 300 participants.
Median target enrolment is 300 among the 18 trials that report a genuine target (sentinel values excluded). 7 of those (38.9%) plan for fewer than 100 participants.
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Chronic Migraine research is mostly interventional.
16 interventional and 2 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
18 total, page 1 of 1
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
Brown University
NCT05754190
A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine
Merz Therapeutics
NCT07018713
Analysis of Headache Chronification With Imaging, Deep Phenotyping, and Proteomics
Stanford University
NCT03231241
A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults
Ipsen
NCT06625060
A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years
AbbVie
NCT06810505
Responding With Evidence and Access for Childhood Headaches
Children's Hospital Medical Center, Cincinnati
NCT05889624
Mind Body Balance for Pediatric Migraine
Children's Hospital Medical Center, Cincinnati
NCT04715685
BOTOX® vs. XEOMIN® for Chronic Migraine
Naval Medical Center Camp Lejeune
NCT05598723
Investigation and Modulation of the Central Mu-Opioid Mechanism in Migraine (in Vivo)
University of Michigan
NCT05769348
Determining the Utility of a Behavioral Intervention in Chronic Migraine
Mayo Clinic
NCT05415020
Acceptance and Commitment Therapy to Improve Disability in Chronic Migraine
Brigham and Women's Hospital
NCT06795867
A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults
Ipsen
NCT06047444
A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine
Eli Lilly and Company
NCT04616326
Brief Interventions in Chronic Migraine
University of Michigan
NCT05979337
Non-Invasive Neurostimulation for the Prevention of Chronic Migraine
ElectroCore
NCT01667250
Biofeedback-VR for Treatment of Chronic Migraine
University of Washington
NCT05720819
Efficacy of Behavioral Insomnia Treatment for Chronic Migraine
Daniel Riche
NCT01314651
Calcitonin Gene-related Peptide Levels in Chronic Migraine
Cady, Roger, M.D.
NCT01071096
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 5 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Chronic Migraine records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Chronic Migraine trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Chronic Migraine page
18 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 11 Chronic Migraine trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Ipsen sponsors the most Chronic Migraine trials on record, review their full trial history before evaluating a specific study. See Ipsen's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Migraine condition card totals 18 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.