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NCT07018713 · ClinicalTrials.gov registry record · Phase 3

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

A Phase 3 study of Chronic Migraine, sponsored by Merz Therapeutics.

Recruiting
Registry status
Phase 3
Development phase
780
Enrollment target
20
Study locations

NCT07018713 is a Phase 3 study of Chronic Migraine that is actively recruiting participants, run by Merz Therapeutics. The registered enrollment target is 780 participants, above the 298-participant average among 17 other Chronic Migraine trials with a reported enrollment target (162% higher). The trial reports 20 study locations across 9 states.

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The verdict

NCT07018713, a Phase 3 study of Chronic Migraine, is actively recruiting participants, sponsored by Merz Therapeutics.

RECRUITING
Registry status
Phase 3
Development phase
780 participants
Enrollment target
20
Study locations

Study Summary

In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections. Trial details include: * Trial duration: 52 to 55 weeks; * Screening period: 4 to 5 weeks; * Treatment duration: 4 treatments, each about 12 weeks apart; and * Visit frequency: about every 4 weeks, 14 visits in total. The first and last visit and the 4 treatment visits are on-site, the other 8 visits are remote by phone / video call.

Conditions Studied

Chronic Migraine

Interventions

  • DRUG Placebo
  • DRUG Xeomin

Study Locations (20)

Florida

  • Northwest Florida Clinical Research Group, Merz Investigational Site #0010286 - Gulf Breeze
  • Nexus Clinical Research Center, Merz Investigational Site #0010514 - Homestead
  • Jacksonville Center for Clinical Research, Merz Investigational Site #0010515 - Jacksonville
  • Clinical Research of Central Florida, Merz Investigational Site #0010532 - Lakeland
  • American Research Institute, Merz Investigational Site #0010492 - Miami
  • Premiere Research Institute at Palm Beach Neurology, Merz Investigational Site #0010499 - West Palm Beach

California

  • Chemidox Clinical Trials Inc, Merz Investigational Site #0010488 - Lancaster
  • Clinical Research Institute, Merz Investigational Site #0010487 - Los Angeles
  • BNL Health, Merz Investigational Site #0010501 - Los Angeles
  • Clinical Trials Management Services, Merz Investigational Site #0010526 - Thousand Oaks

Connecticut

  • Hasbani Neurology, Merz Investigational Site #0010509 - New Haven
  • Yale Center for Clinical Investigations, Merz Investigational Site #0010527 - New Haven
  • New England Institute Neurology and Headache, Merz Investigational Site #0010441 - Stamford

Arizona

  • TrialSphere Corp, Merz Investigational Site #0010513 - Chandler
  • Arizona Neuroscience Research, Merz Investigational Site #0010521 - Phoenix

Arkansas

  • Baptist Health Medical Center, Merz Investigational Site #0010520 - Little Rock

Georgia

  • Accel Research - NeuroStudies, Merz Investigational Site #0010523 - Decatur

Hawaii

  • Hawaii Pacific Neuroscience, Merz Investigational Site #0010510 - Honolulu

Kansas

  • Kansas Institute of Research,, Merz Investigational Site #0010495 - Overland Park

Trial Details

FieldValue
Enrollment Target 780 participants
Start Date 2025-08-21
Est. Completion 2028-03
Phase Phase 3

Sponsor

Merz Therapeutics

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07018713

The ClinicalTrials.gov registry entry for NCT07018713 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 780 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 298-participant average among 17 other Chronic Migraine trials with a reported enrollment target (162% higher). The listed sponsor is Merz Therapeutics, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Chronic Migraine appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT07018713 reports 20 study locations spanning 9 distinct geographic areas - top geographies include Florida, California, Connecticut.

Frequently Asked Questions

What is clinical trial NCT07018713 about?

NCT07018713 is a clinical study titled "A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine". In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections. Trial details include: * Trial duration:...

What is the current status of trial NCT07018713?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 780 participants. The study started on 2025-08-21. Estimated completion is 2028-03.

What conditions does trial NCT07018713 study?

This clinical trial studies the following conditions: Chronic Migraine.

What interventions are being tested in trial NCT07018713?

The interventions under investigation include: Placebo (DRUG), Xeomin (DRUG).

Who is sponsoring clinical trial NCT07018713?

This trial is sponsored by Merz Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07018713 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.