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RECRUITING Phase 3

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

NCT07018713 · View on ClinicalTrials.gov ↗

Study Summary

In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections. Trial details include: * Trial duration: 52 to 55 weeks; * Screening period: 4 to 5 weeks; * Treatment duration: 4 treatments, each about 12 weeks apart; and * Visit frequency: about every 4 weeks, 14 visits in total. The first and last visit and the 4 treatment visits are on-site, the other 8 visits are remote by phone / video call.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Xeomin

Study Locations (20)

Florida

  • Northwest Florida Clinical Research Group, Merz Investigational Site #0010286 — Gulf Breeze
  • Nexus Clinical Research Center, Merz Investigational Site #0010514 — Homestead
  • Jacksonville Center for Clinical Research, Merz Investigational Site #0010515 — Jacksonville
  • Clinical Research of Central Florida, Merz Investigational Site #0010532 — Lakeland
  • American Research Institute, Merz Investigational Site #0010492 — Miami
  • Premiere Research Institute at Palm Beach Neurology, Merz Investigational Site #0010499 — West Palm Beach

California

  • Chemidox Clinical Trials Inc, Merz Investigational Site #0010488 — Lancaster
  • Clinical Research Institute, Merz Investigational Site #0010487 — Los Angeles
  • BNL Health, Merz Investigational Site #0010501 — Los Angeles
  • Clinical Trials Management Services, Merz Investigational Site #0010526 — Thousand Oaks

Connecticut

  • Hasbani Neurology, Merz Investigational Site #0010509 — New Haven
  • Yale Center for Clinical Investigations, Merz Investigational Site #0010527 — New Haven
  • New England Institute Neurology and Headache, Merz Investigational Site #0010441 — Stamford

Arizona

  • TrialSphere Corp, Merz Investigational Site #0010513 — Chandler
  • Arizona Neuroscience Research, Merz Investigational Site #0010521 — Phoenix

Arkansas

  • Baptist Health Medical Center, Merz Investigational Site #0010520 — Little Rock

Georgia

  • Accel Research - NeuroStudies, Merz Investigational Site #0010523 — Decatur

Hawaii

  • Hawaii Pacific Neuroscience, Merz Investigational Site #0010510 — Honolulu

Kansas

  • Kansas Institute of Research,, Merz Investigational Site #0010495 — Overland Park

Trial Details

FieldValue
Enrollment Target 780 participants
Start Date 2025-08-21
Est. Completion 2028-03
Phase Phase 3

Sponsor

Merz Therapeutics

29 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07018713

The ClinicalTrials.gov registry entry for NCT07018713 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 780 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merz Therapeutics, which has 29 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Chronic Migraine appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07018713 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Florida, California, Connecticut. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07018713 about?

NCT07018713 is a clinical study titled "A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine". In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections. Trial details include: * Trial duration:...

What is the current status of trial NCT07018713?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 780 participants. The study started on 2025-08-21. Estimated completion is 2028-03.

What conditions does trial NCT07018713 study?

This clinical trial studies the following conditions: Chronic Migraine. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07018713?

The interventions under investigation include: Placebo (DRUG), Xeomin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07018713?

This trial is sponsored by Merz Therapeutics, which has 29 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07018713 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial