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NCT05769348 · ClinicalTrials.gov registry record · NA

Investigation and Modulation of the Central Mu-Opioid Mechanism in Migraine (in Vivo)

A NA study of Chronic Migraine, sponsored by University of Michigan.

Recruiting
Registry status
NA
Development phase
80
Enrollment target
1
Study location

NCT05769348 is a NA study of Chronic Migraine that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 80 participants, below the 339-participant average among 17 other Chronic Migraine trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05769348, a NA study of Chronic Migraine, is actively recruiting participants, sponsored by University of Michigan.

RECRUITING
Registry status
NA
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

This study investigates whether unilateral and bilateral non-invasive brain stimulation, given for 20 minutes/once per day for twenty days (M-F) can reduce migraine pain. Fourty patients will receive treatment (20 unilateral treatment, and 20 bilateral treatment), while twenty will receive a "sham" procedure. Another 20 Episodic Migraine patients will be recruited for the observational aim of the study which does not include brain stimulation.

Conditions Studied

Chronic Migraine

Interventions

  • DEVICE HD-tDCS Active Protocol
  • DEVICE HD-tDCS Sham Protocol

Study Locations (1)

Michigan

  • University of Michigan - Ann Arbor

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2023-01-26
Est. Completion 2026-12-30
Phase NA

Sponsor

University of Michigan

1,327 total trials

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What the Registry Record Tells You About NCT05769348

The ClinicalTrials.gov registry entry for NCT05769348 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 339-participant average among 17 other Chronic Migraine trials with a reported enrollment target (76% lower). The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Chronic Migraine appearing as the primary indexed condition, and to 2 interventions - of which HD-tDCS Active Protocol is the first listed.

NCT05769348 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT05769348 about?

NCT05769348 is a clinical study titled "Investigation and Modulation of the Central Mu-Opioid Mechanism in Migraine (in Vivo)". This study investigates whether unilateral and bilateral non-invasive brain stimulation, given for 20 minutes/once per day for twenty days (M-F) can reduce migraine pain. Fourty patients will receive treatment (20 unilateral treatment, and 20 bilateral treatment), while twenty will receive a "sham" ...

What is the current status of trial NCT05769348?

This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2023-01-26. Estimated completion is 2026-12-30.

What conditions does trial NCT05769348 study?

This clinical trial studies the following conditions: Chronic Migraine.

What interventions are being tested in trial NCT05769348?

The interventions under investigation include: HD-tDCS Active Protocol (DEVICE), HD-tDCS Sham Protocol (DEVICE).

Who is sponsoring clinical trial NCT05769348?

This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05769348 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.