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ClinicalTrials.gov 11 recruiting now early-phase tilt small index

Breast Cancer Metastatic: early-phase trial registry

11 of 18 indexed Breast Cancer Metastatic trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #953 of 28,707 conditions by registered trial count.

18 US clinical trials · 11 currently recruiting · #953 of 28,707 conditions by registered trial count

Breast Cancer Metastatic: 18 US clinical trials tracked, 11 recruiting.

Breast Cancer Metastatic is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most active sponsor is Oncolytics Biotech, running 1 of these trials.

Enrollment posture brief

Registry condition breast-cancer-metastatic

OPEN 11 | RECR 61% | LATE 1 | EARLY 14 | RANK #953 | SPON 1

Nearest open-share peer: Child Behavior (61% recruiting · 18 trials)

Breast Cancer Metastatic (th…61%Arrhythmias, Cardiac27.8%Androgenetic Alopecia16.7%Anemia, Sickle Cell16.7%Acquired Immunodeficiency Sy5.6%
Open-enrollment share among volume-matched conditions near Breast Cancer Metastatic

Breast Cancer Metastatic lists 11 open slots (61% of 18 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Breast Cancer Metastatic on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Breast Cancer Metastatic is recruiting above its size-band peers.

    11 of 18 indexed trials (61.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Breast Cancer Metastatic trials is spread across many organizations.

    Oncolytics Biotech accounts for 1 of 18 trials (5.6%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Most Breast Cancer Metastatic trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 18 trials that report a genuine target (sentinel values excluded). 13 of those (72.2%) plan for fewer than 100 participants.

  4. Breast Cancer Metastatic research is mostly interventional.

    16 interventional and 2 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 19Phase 25Phase 31

Open and recent trials

18 total, page 1 of 1

RECRUITING Phase 3 404 participants

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

BriaCell Therapeutics Corporation

NCT06072612

RECRUITING NA 200 participants

Nutrition Awareness Among Women With Non-Metastatic Breast Cancer

UNC Lineberger Comprehensive Cancer Center

NCT07389967

RECRUITING Phase 1 150 participants

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Incyclix Bio

NCT05735080

RECRUITING Phase 1 80 participants

ASPEN-09: A Study of Evorpacept in Combination With Anti-cancer Therapies in Advanced / Metastatic Malignancies

ALX Oncology

NCT07007559

RECRUITING Phase 2 72 participants

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Dana-Farber Cancer Institute

NCT06439693

RECRUITING Phase 1 70 participants

SLV-154 Treatment of Metastatic Solid Tumors

Solve Therapeutics

NCT06771219

RECRUITING Phase 2 40 participants

Trial of Trastuzumab Deruxtecan in Previously Treated HER2

Yale University

NCT06750484

RECRUITING Phase 1 35 participants

Clinical Trial of Avasopasem in Patients With Metastatic Hormone Receptor Positive Breast Cancer With Progression on a CDK 4/6 Inhibitor and Hormonal Therapy

The University of Texas Health Science Center at San Antonio

NCT07137871

RECRUITING Phase 1 28 participants

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT06678269

RECRUITING Phase 1 24 participants

SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

General Oncology

NCT04150042

RECRUITING Phase 1 20 participants

A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer

Calibr, a division of Scripps Research

NCT06878248

ACTIVE NOT RECRUITING 166 participants

Screening For BCRL In Targeted Therapy For Breast Cancer

Massachusetts General Hospital

NCT05142800

ACTIVE NOT RECRUITING 50 participants

Personalized Detection of ctDNA for Patients With HER2-Positive Metastatic Breast Cancer Who Achieved Durable Response by Anti-HER2 Treatment (HER2 CR)

Nagoya City University

NCT06663787

ACTIVE NOT RECRUITING Phase 2 48 participants

A Study to Assess Overall Response Rate by Inducing an Inflammatory Phenotype in Metastatic BReast cAnCEr With the Oncolytic Reovirus PeLareorEp in CombinaTion With Anti-PD-L1 Avelumab and Paclitaxel - BRACELET-1 Study

Oncolytics Biotech

NCT04215146

ACTIVE NOT RECRUITING Phase 1 28 participants

Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer

The Methodist Hospital Research Institute

NCT03742245

ACTIVE NOT RECRUITING Phase 2 28 participants

A Single-arm Phase II Trial of SAcituzumab Govitecan and Trastuzumab for HER2+ Metastatic Breast Cancer After Trastuzumab dEruxtEcaN (SATEEN)

Adrienne G. Waks

NCT06100874

COMPLETED Phase 2 105 participants

MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer.

Merus B.V.

NCT03321981

COMPLETED Phase 1 23 participants

DZD1516 in Combination With Trastuzumab and Capecitabine, or in Combination With T-DM1, in Patients With Metastatic HER2 Positive Breast Cancer

Dizal Pharmaceuticals

NCT04509596

Phase Distribution

PhaseTrial count
Phase 1 9
Phase 2 5
Phase 3 1

Named interventions

Most-linked intervention names on Breast Cancer Metastatic records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Paclitaxel Drug
3 trials
Trastuzumab Drug
3 trials
Abemaciclib Drug
2 trials
Zenocutuzumab Drug
1 trials
DZD1516 mono therapy in Part A, DZD1516 in combination with trastuzumab and/or capecitabine in Part B, DZD1516 in combination with T-DM1 in Part C Drug
1 trials
SIgnatera Diagnostic test
1 trials
Trastuzumab (Herceptin) Drug
1 trials
Trastuzumab and Hyaluronidase-oysk Drug
1 trials

US sites by state

Facility locations filed on Breast Cancer Metastatic trials. A trial with sites in several states counts in each.

New York 7 trials
Texas 6 trials
Massachusetts 5 trials
California 4 trials
Washington 3 trials
Ohio 3 trials
New Jersey 3 trials
Indiana 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Breast Cancer Metastatic page

18 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 11 Breast Cancer Metastatic trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Oncolytics Biotech sponsors the most Breast Cancer Metastatic trials on record, review their full trial history before evaluating a specific study. See Oncolytics Biotech's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Breast Cancer Metastatic condition card totals 18 registered trials; most-linked intervention Paclitaxel; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.