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ClinicalTrials.gov 11 recruiting now official registry

Breast Cancer Metastatic clinical trials

11 of 18 indexed Breast Cancer Metastatic trials are currently recruiting.

18 US clinical trials · 11 currently recruiting

Breast Cancer Metastatic is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most active sponsor is Oncolytics Biotech, running 1 of these trials.

The research picture

Breast Cancer Metastatic has 18 registered US clinical trials, 11 of them open to new participants right now, about 61% of the total.

11
recruiting participants now
61%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
1
top sponsor: Oncolytics Biotech
Phase 19Phase 25Phase 31

Active & Recent Trials

18 total, page 1 of 1

RECRUITING Phase 3 404 participants

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

BriaCell Therapeutics Corporation

NCT06072612

RECRUITING NA 200 participants

Nutrition Awareness Among Women With Non-Metastatic Breast Cancer

UNC Lineberger Comprehensive Cancer Center

NCT07389967

RECRUITING Phase 1 150 participants

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

Incyclix Bio

NCT05735080

RECRUITING Phase 1 80 participants

ASPEN-09: A Study of Evorpacept in Combination With Anti-cancer Therapies in Advanced / Metastatic Malignancies

ALX Oncology

NCT07007559

RECRUITING Phase 2 72 participants

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Dana-Farber Cancer Institute

NCT06439693

RECRUITING Phase 1 70 participants

SLV-154 Treatment of Metastatic Solid Tumors

Solve Therapeutics

NCT06771219

RECRUITING Phase 2 40 participants

Trial of Trastuzumab Deruxtecan in Previously Treated HER2

Yale University

NCT06750484

RECRUITING Phase 1 35 participants

Clinical Trial of Avasopasem in Patients With Metastatic Hormone Receptor Positive Breast Cancer With Progression on a CDK 4/6 Inhibitor and Hormonal Therapy

The University of Texas Health Science Center at San Antonio

NCT07137871

RECRUITING Phase 1 28 participants

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT06678269

RECRUITING Phase 1 24 participants

SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

General Oncology

NCT04150042

RECRUITING Phase 1 20 participants

A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer

Calibr, a division of Scripps Research

NCT06878248

ACTIVE NOT RECRUITING 166 participants

Screening For BCRL In Targeted Therapy For Breast Cancer

Massachusetts General Hospital

NCT05142800

ACTIVE NOT RECRUITING 50 participants

Personalized Detection of ctDNA for Patients With HER2-Positive Metastatic Breast Cancer Who Achieved Durable Response by Anti-HER2 Treatment (HER2 CR)

Nagoya City University

NCT06663787

ACTIVE NOT RECRUITING Phase 2 48 participants

A Study to Assess Overall Response Rate by Inducing an Inflammatory Phenotype in Metastatic BReast cAnCEr With the Oncolytic Reovirus PeLareorEp in CombinaTion With Anti-PD-L1 Avelumab and Paclitaxel - BRACELET-1 Study

Oncolytics Biotech

NCT04215146

ACTIVE NOT RECRUITING Phase 1 28 participants

Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer

The Methodist Hospital Research Institute

NCT03742245

ACTIVE NOT RECRUITING Phase 2 28 participants

A Single-arm Phase II Trial of SAcituzumab Govitecan and Trastuzumab for HER2+ Metastatic Breast Cancer After Trastuzumab dEruxtEcaN (SATEEN)

Adrienne G. Waks

NCT06100874

COMPLETED Phase 2 105 participants

MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer.

Merus B.V.

NCT03321981

COMPLETED Phase 1 23 participants

DZD1516 in Combination With Trastuzumab and Capecitabine, or in Combination With T-DM1, in Patients With Metastatic HER2 Positive Breast Cancer

Dizal Pharmaceuticals

NCT04509596

Phase Distribution

PhaseTrial count
Phase 1 9
Phase 2 5
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Breast Cancer Metastatic Trial Landscape

18 indexed Breast Cancer Metastatic studies · 11 recruiting (61%).

Phase mix: 1 late (III/IV) vs 14 early (I/II).

Top sponsor: Oncolytics Biotech (1 trial), 9 others listed. 18 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Breast Cancer Metastatic?

PlainTrial tracks 18 US clinical trials for Breast Cancer Metastatic, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Breast Cancer Metastatic?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.