Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01667250 · ClinicalTrials.gov registry record · NA
Non-Invasive Neurostimulation for the Prevention of Chronic Migraine
A NA study of Chronic Migraine, sponsored by ElectroCore.
- Completed
- Registry status
- NA
- Development phase
- 59
- Enrollment target
- 6
- Study locations
NCT01667250: Completed NA study of Chronic Migraine, sponsored by ElectroCore.
NCT01667250 is a NA study of Chronic Migraine that has completed, run by ElectroCore. The registered enrollment target is 59 participants, below the 340-participant average among 17 other Chronic Migraine trials with a reported enrollment target (83% lower). The trial reports 6 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01667250, a NA study of Chronic Migraine, has completed, sponsored by ElectroCore.
- COMPLETED
- Registry status
- NA
- Development phase
- 59 participants
- Enrollment target
- 6
- Study locations
Study Summary
The purpose of this multi-center, prospective, double-blind, randomized, sham-controlled pilot study is to study feasibility and collect preliminary clinical data related to the safety and clinical benefits of daily use of non-invasive vagal nerve stimulation with the GammaCore device for the prevention of chronic migraine, and to support the development and approval of a larger pivotal study.
Primary Outcome
Safety was assessed by collecting Adverse Effects
Conditions Studied
Interventions
- DEVICE GammaCore Active Device
- DEVICE GammaCore Sham Device
Study Locations (6)
California
- UCSF Headache Center - San Francisco
Michigan
- Michigan Head Pain & Neurological Institute - Ann Arbor
Missouri
- Headache Care Center - Springfield
New York
- Montefiore Headache Center - The Bronx
North Carolina
- Carolina Headache Institute - Chapel Hill
Pennsylvania
- Thomas Jefferson Headache Center - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 59 participants |
| Start Date | 2012-10 |
| Est. Completion | 2014-05 |
| Phase | NA |
What the finished NCT01667250 record still lists
NCT01667250 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 59 participants, a relatively small participant target, below the 340-participant average among 17 other Chronic Migraine trials with a reported enrollment target (83% lower).
The record links to 1 condition, with Chronic Migraine appearing as the primary indexed condition, and to 2 interventions - of which GammaCore Active Device is the first listed.
NCT01667250 lists 6 locations in 6 states (California, Michigan, Missouri).
Frequently Asked Questions
What is clinical trial NCT01667250 about?
NCT01667250 is a clinical study titled "Non-Invasive Neurostimulation for the Prevention of Chronic Migraine". The purpose of this multi-center, prospective, double-blind, randomized, sham-controlled pilot study is to study feasibility and collect preliminary clinical data related to the safety and clinical benefits of daily use of non-invasive vagal nerve stimulation with the GammaCore device for the preven...
What is the current status of trial NCT01667250?
This trial is currently completed. It is a NA study. The enrollment target is 59 participants. The study started on 2012-10. Estimated completion is 2014-05.
What conditions does trial NCT01667250 study?
This clinical trial studies the following conditions: Chronic Migraine.
What interventions are being tested in trial NCT01667250?
The interventions under investigation include: GammaCore Active Device (DEVICE), GammaCore Sham Device (DEVICE).
Who is sponsoring clinical trial NCT01667250?
This trial is sponsored by ElectroCore, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01667250 being conducted?
This trial has 6 study locations across California, Michigan, Missouri, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Migraine
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01667250's enrollment target sits among peer trials
59 14th of 17 higher than 4 of 17 other Chronic Migraine trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Migraine trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Responding With Evidence and Access for Childhood Headaches
RECRUITING · NA
-
Determining the Utility of a Behavioral Intervention in Chronic Migraine
RECRUITING · NA
-
Investigation and Modulation of the Central Mu-Opioid Mechanism in Migraine (in Vivo)
RECRUITING · NA
-
Acceptance and Commitment Therapy to Improve Disability in Chronic Migraine
RECRUITING · NA
-
Mind Body Balance for Pediatric Migraine
RECRUITING · NA
-
Brief Interventions in Chronic Migraine
ACTIVE NOT RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03801083 · 59 participants · Phase 2
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract Cancers
- NCT04332367 · 59 participants · Phase 2
Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance
- NCT05489575 · 59 participants · NA
CPAP for the Treatment of Supine Hypertension
- NCT06721689 · 59 participants · Phase 1
PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia