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NCT04600323 · ClinicalTrials.gov registry record · Early Phase 1
Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD
A Early Phase 1 study of Chronic Kidney Disease and Cognitive Dysfunction, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 34
- Enrollment target
- 1
- Study location
NCT04600323 is a Early Phase 1 study of Chronic Kidney Disease and Cognitive Dysfunction that has completed, run by University of Colorado, Denver. The registered enrollment target is 34 participants, below the 3,206-participant average among 101 other Chronic Kidney Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04600323, a Early Phase 1 study of Chronic Kidney Disease and Cognitive Dysfunction, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 34 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a pilot, randomized, double-blinded, placebo-controlled, 12-month trial of 50 patients with CKD stage 3b-4 with metabolic acidosis to examine the effect of sodium bicarbonate therapy on cognitive and cerebrovascular function.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Sodium Bicarbonate Tablets
Study Locations (1)
Colorado
- University of Colorado Anschutz Medical Campus - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2021-02-01 |
| Est. Completion | 2023-08-30 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04600323
The ClinicalTrials.gov registry entry for NCT04600323 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,206-participant average among 101 other Chronic Kidney Disease trials with a reported enrollment target (99% lower). The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Chronic Kidney Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04600323 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.
Frequently Asked Questions
What is clinical trial NCT04600323 about?
NCT04600323 is a clinical study titled "Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD". This is a pilot, randomized, double-blinded, placebo-controlled, 12-month trial of 50 patients with CKD stage 3b-4 with metabolic acidosis to examine the effect of sodium bicarbonate therapy on cognitive and cerebrovascular function.
What is the current status of trial NCT04600323?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 34 participants. The study started on 2021-02-01. Estimated completion is 2023-08-30.
What conditions does trial NCT04600323 study?
This clinical trial studies the following conditions: Chronic Kidney Disease, Cognitive Dysfunction, Metabolic Acidosis.
What interventions are being tested in trial NCT04600323?
The interventions under investigation include: Placebo (DRUG), Sodium Bicarbonate Tablets (DRUG).
Who is sponsoring clinical trial NCT04600323?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04600323 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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