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A Study of Renal Autologous Cell Therapy (REACT) in Type 2 Diabetics With Chronic Kidney Disease
NCT02836574 · View on ClinicalTrials.gov ↗
Study Summary
To assess the safety and efficacy of up to two REACT injections given 6 months (+4 weeks) apart and delivered into the biopsied kidney using a percutaneous approach in participants with Type 2 Diabetes Mellitus (T2DM) and Chronic Kidney Disease (CKD).
Conditions Studied
Interventions
- BIOLOGICAL Renal Autologous Cell Therapy (REACT)
- PROCEDURE Renal Biopsy
Study Locations (16)
Michigan
- University of Michigan — Ann Arbor
- Paragon Health — Kalamazoo
Arizona
- University of Arizona — Tucson
Colorado
- Kidney Associates of Colorado — Denver
Connecticut
- Yale Univeristy — New Haven
Florida
- University of Florida — Gainesville
Idaho
- Boise Kidney and Hypertension Institute — Meridian
Illinois
- University of Chicago Medical Center — Chicago
Kentucky
- University of Louisville — Louisville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 83 participants |
| Start Date | 2016-09 |
| Est. Completion | 2023-12 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02836574
The ClinicalTrials.gov registry entry for NCT02836574 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 83 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Prokidney, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Type 2 Diabetes Mellitus appearing as the primary indexed condition, and to 2 interventions — of which Renal Autologous Cell Therapy (REACT) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02836574 reports 16 study locations spanning 15 distinct geographic areas — top geographies include Michigan, Arizona, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02836574 about?
NCT02836574 is a clinical study titled "A Study of Renal Autologous Cell Therapy (REACT) in Type 2 Diabetics With Chronic Kidney Disease". To assess the safety and efficacy of up to two REACT injections given 6 months (+4 weeks) apart and delivered into the biopsied kidney using a percutaneous approach in participants with Type 2 Diabetes Mellitus (T2DM) and Chronic Kidney Disease (CKD).
What is the current status of trial NCT02836574?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 83 participants. The study started on 2016-09. Estimated completion is 2023-12.
What conditions does trial NCT02836574 study?
This clinical trial studies the following conditions: Type 2 Diabetes Mellitus, Chronic Kidney Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02836574?
The interventions under investigation include: Renal Autologous Cell Therapy (REACT) (BIOLOGICAL), Renal Biopsy (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02836574?
This trial is sponsored by Prokidney, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02836574 being conducted?
This trial has 16 study locations across Arizona, Colorado, Connecticut, Florida, Idaho. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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