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NCT00421733 · ClinicalTrials.gov registry record · Phase 2

The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitors

A Phase 2 study of Chronic Kidney Disease and Diabetic Nephropathy, sponsored by Abbott.

Completed
Registry status
Phase 2
Development phase
281
Enrollment target
20
Study locations

NCT00421733 is a Phase 2 study of Chronic Kidney Disease and Diabetic Nephropathy that has completed, run by Abbott. The registered enrollment target is 281 participants, below the 3,204-participant average among 101 other Chronic Kidney Disease trials with a reported enrollment target (91% lower). The trial reports 20 study locations across 13 states.

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The verdict

NCT00421733, a Phase 2 study of Chronic Kidney Disease and Diabetic Nephropathy, has completed, sponsored by Abbott.

COMPLETED
Registry status
Phase 2
Development phase
281 participants
Enrollment target
20
Study locations

Study Summary

The study objective was to evaluate the safety of paricalcitol capsules and the efficacy of paricalcitol capsules for albuminuria reduction in patients with Chronic Kidney Disease (CKD) who have Type 2 diabetic nephropathy and are receiving optimal angiotensin converting enzyme (ACE) inhibitor and/or angiotensin II receptor blocker (ARB) therapy.

Interventions

  • DRUG Placebo
  • DRUG Zemplar (paricalcitol ) capsules
  • DRUG Zemplar (paricalcitol) capsules

Study Locations (20)

Florida

  • Site Reference ID/Investigator# 853 - Hudson
  • Site Reference ID/Investigator# 867 - Lauderdale Lakes
  • Site Reference ID/Investigator# 857 - Pembroke Pines
  • Site Reference ID/Investigator# 8901 - West Palm Beach

North Carolina

  • Site Reference ID/Investigator# 866 - Charlotte
  • Site Reference ID/Investigator# 8039 - Greenville
  • Site Reference ID/Investigator# 8053 - Morehead City

California

  • Site Reference ID/Investigator# 864 - Fountain Valley
  • Site Reference ID/Investigator# 7291 - Yuba City

Illinois

  • Site Reference ID/Investigator# 2531 - Chicago
  • Site Reference ID/Investigator# 3371 - Evanston

Arizona

  • Site Reference ID/Investigator# 862 - Phoenix

Georgia

  • Site Reference ID/Investigator# 7113 - Roswell

Indiana

  • Site Reference ID/Investigator# 869 - Indianapolis

Louisiana

  • Site Reference ID/Investigator# 8054 - Baton Rouge

Trial Details

FieldValue
Enrollment Target 281 participants
Start Date 2006-12
Est. Completion 2009-06
Phase Phase 2

Sponsor

Abbott

181 total trials

What the Registry Record Tells You About NCT00421733

The ClinicalTrials.gov registry entry for NCT00421733 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 281 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,204-participant average among 101 other Chronic Kidney Disease trials with a reported enrollment target (91% lower). The listed sponsor is Abbott, which has 181 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Chronic Kidney Disease appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT00421733 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Florida, North Carolina, California.

Frequently Asked Questions

What is clinical trial NCT00421733 about?

NCT00421733 is a clinical study titled "The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitors". The study objective was to evaluate the safety of paricalcitol capsules and the efficacy of paricalcitol capsules for albuminuria reduction in patients with Chronic Kidney Disease (CKD) who have Type 2 diabetic nephropathy and are receiving optimal angiotensin converting enzyme (ACE) inhibitor and/o...

What is the current status of trial NCT00421733?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 281 participants. The study started on 2006-12. Estimated completion is 2009-06.

What conditions does trial NCT00421733 study?

This clinical trial studies the following conditions: Chronic Kidney Disease, Diabetic Nephropathy.

What interventions are being tested in trial NCT00421733?

The interventions under investigation include: Placebo (DRUG), Zemplar (paricalcitol ) capsules (DRUG), Zemplar (paricalcitol) capsules (DRUG).

Who is sponsoring clinical trial NCT00421733?

This trial is sponsored by Abbott, which has 181 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00421733 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.