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NCT05557877 · ClinicalTrials.gov registry record · Phase 2
Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
A Phase 2 study of Breast Carcinoma, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
- 4
- Study locations
NCT05557877: Recruiting Phase 2 study of Breast Carcinoma, sponsored by Mayo Clinic.
NCT05557877 is a Phase 2 study of Breast Carcinoma that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 100 participants, below the 770-participant average among 106 other Breast Carcinoma trials with a reported enrollment target (87% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05557877, a Phase 2 study of Breast Carcinoma, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
- 4
- Study locations
Study Summary
This phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) women planning to have a breast biopsy. Chronic inflammation may increase the risk of postpartum related breast cancer. Low-dose aspirin is a non-steroidal anti-inflammatory drug. Giving low-dose aspirin may affect markers of inflammation in blood and tissue and may prevent postpartum related breast cancer.
Primary Outcome
Assessed using pre- versus post-treatment PRBC scores. Patients who are eligible, consented, received at least 70% of the study treatment, and provided both a pre- and post-intervention tissue specimen will be evaluated for this outcome.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- PROCEDURE Biopsy
- OTHER Questionnaire Administration
- DRUG Low-Dose Aspirin
Study Locations (4)
Arizona
- Mayo Clinic in Arizona - Scottsdale
Florida
- Mayo Clinic in Florida - Jacksonville
Indiana
- Indiana University Simon Comprehensive Cancer Center - Indianapolis
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-03-09 |
| Est. Completion | 2027-01-30 |
| Phase | Phase 2 |
What NCT05557877 shows while recruiting
NCT05557877 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 770-participant average among 106 other Breast Carcinoma trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Breast Carcinoma appearing as the primary indexed condition, and to 4 interventions - of which Biospecimen Collection is the first listed.
NCT05557877 reports a single indexed study location in Arizona, Florida, Indiana.
Frequently Asked Questions
What is clinical trial NCT05557877 about?
NCT05557877 is a clinical study titled "Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer". This phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) women planning to have a breast biopsy. Chronic inflammation may increase the risk of postpartum related breast cancer. Low-dose aspirin is a non-steroidal anti-inflammatory drug. G...
What is the current status of trial NCT05557877?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2023-03-09. Estimated completion is 2027-01-30.
What conditions does trial NCT05557877 study?
This clinical trial studies the following conditions: Breast Carcinoma.
What interventions are being tested in trial NCT05557877?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Biopsy (PROCEDURE), Questionnaire Administration (OTHER), Low-Dose Aspirin (DRUG).
Who is sponsoring clinical trial NCT05557877?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05557877 being conducted?
This trial has 4 study locations across Arizona, Florida, Indiana, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05557877's enrollment target sits among peer trials
100 59th of 106 higher than 45 of 106 other Breast Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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