Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Bipolar Disorder: later-stage trial registry
37 of 163 indexed Bipolar Disorder trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #66 of 28,707 conditions by registered trial count.
163 US clinical trials · 37 currently recruiting · #66 of 28,707 conditions by registered trial count
Bipolar Disorder: 163 US clinical trials tracked, 37 recruiting.
Bipolar Disorder is the subject of 163 registered US clinical trials on ClinicalTrials.gov, 37 of them currently open to new participants. 45 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 11 of these trials.
Enrollment posture brief
Registry condition bipolar-disorder
OPEN 37 | RECR 23% | LATE 45 | EARLY 15 | RANK #66 | SPON 11
Volume-matched condition peers
Nearest open-share peer: Hypogonadism (23% recruiting · 22 trials)
Bipolar Disorder lists 37 open slots (23% of 163 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Bipolar Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Bipolar Disorder is recruiting below its size-band peers.
37 of 163 indexed trials (22.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Bipolar Disorder trials is spread across many organizations.
Massachusetts General Hospital accounts for 11 of 163 trials (6.7%). 73 distinct sponsors appear on at least one study for this condition label.
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Typical Bipolar Disorder enrolment sits around 75 participants.
Median target enrolment is 75 among the 163 trials that report a genuine target (sentinel values excluded). 92 of those (56.4%) plan for fewer than 100 participants.
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Bipolar Disorder research is mostly interventional.
133 interventional and 30 observational studies make up this index (81.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
163 total, page 4 of 4
Geodon in Weight Loss Study for Bipolar Disorders
Stanford University
NCT00472641
Financial Incentives to Improve Medication Adherence
Northwell Health
NCT04191876
Treatment With Quetiapine for Youth With Substance Use Disorders and Severe Mood Dysregulation
Boston Medical Center
NCT02845453
Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness
Stanford University
NCT03935854
A Trial of SAMe for Treatment-Resistant Bipolar Depression
Mclean Hospital
NCT00762268
Ziprasidone for the Treatment of Mania in Children and Adolescents With Bipolar Disorder
Massachusetts General Hospital
NCT00181922
Personal Adherence Evaluation of Medication Use for Adult Bipolar Disorder Patients
Case Western Reserve University
NCT00763581
Drug-drug Interaction Study of Aripiprazole and Lamotrigine in Patients With Bipolar Type I Disorder
Otsuka Pharmaceutical Development & Commercialization
NCT00321516
Brain Stimulation and Cognitive Training - Efficacy
University of Michigan
NCT05111548
Effects of Pentazocine Versus Lorazepam on Manic Symptoms
Mclean Hospital
NCT00431184
Treating Self Injurious Behavior: A Novel Brain Stimulation Approach
New York State Psychiatric Institute
NCT04244786
Circadian Phase in Bipolar Depression: Is it Delayed and Does it Normalize With Remission?
Northwestern University
NCT01784341
Early Detection and Prevention of Mood Disorders in Children of Parents With Bipolar Disorder
New York State Psychiatric Institute
NCT00338806
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 12 |
| Phase 3 | 23 |
| Phase 4 | 22 |
Top Sponsors
Named interventions
Most-linked intervention names on Bipolar Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Bipolar Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Bipolar Disorder page
163 registered trials, 37 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 37 Bipolar Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Massachusetts General Hospital sponsors the most Bipolar Disorder trials on record, review their full trial history before evaluating a specific study. See Massachusetts General Hospital's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Bipolar Disorder condition card totals 163 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.