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NCT05664789 · ClinicalTrials.gov registry record · Phase 2
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial
A Phase 2 study of Autism Spectrum Disorder, sponsored by Stanford University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 144
- Enrollment target
- 1
- Study location
NCT05664789: Recruiting Phase 2 study of Autism Spectrum Disorder, sponsored by Stanford University.
NCT05664789 is a Phase 2 study of Autism Spectrum Disorder that is actively recruiting participants, run by Stanford University. The registered enrollment target is 144 participants, roughly in line with the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05664789, a Phase 2 study of Autism Spectrum Disorder, is actively recruiting participants, sponsored by Stanford University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 144 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise for reducing symptom severity in recent small-scale trials. The findings from this research will shed light on the mechanisms of action underlying the clinical benefits of NAC and the effects of NAC on altering restricted and repetitive behavior symptom severity in children with autism spectrum disorder. This is a 12-week double-blind, randomized, placebo-controlled trial of NAC.
Primary Outcome
Severity of restricted and repetitive behaviors, higher scores indicate more severe behaviors
Conditions Studied
Interventions
- DRUG Placebo
- DRUG N acetyl cysteine
Study Locations (1)
California
- Department of Psychiatry and Behavioral Sciences - Palo Alto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 144 participants |
| Start Date | 2023-04-26 |
| Est. Completion | 2028-07-31 |
| Phase | Phase 2 |
What NCT05664789 shows while recruiting
NCT05664789 is an interventional study that assigns participants to a tested intervention. The registered 144 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target.
The record links to 1 condition, with Autism Spectrum Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05664789 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05664789 about?
NCT05664789 is a clinical study titled "Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial". The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise for reducing symptom severity in recent small-scale trials. The findings ...
What is the current status of trial NCT05664789?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 144 participants. The study started on 2023-04-26. Estimated completion is 2028-07-31.
What conditions does trial NCT05664789 study?
This clinical trial studies the following conditions: Autism Spectrum Disorder.
What interventions are being tested in trial NCT05664789?
The interventions under investigation include: Placebo (DRUG), N acetyl cysteine (DRUG).
Who is sponsoring clinical trial NCT05664789?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05664789 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Autism Spectrum Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05664789's enrollment target sits among peer trials
144 56th of 224 higher than 166 of 224 other Autism Spectrum Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Autism Spectrum Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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