Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Appendicitis: later-stage trial registry
5 of 9 indexed Appendicitis trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,916 of 28,707 conditions by registered trial count.
9 US clinical trials · 5 currently recruiting · #1,916 of 28,707 conditions by registered trial count
Appendicitis: 9 US clinical trials tracked, 5 recruiting.
Appendicitis is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Children's Health, running 1 of these trials.
Enrollment posture brief
Registry condition appendicitis
OPEN 5 | RECR 56% | LATE 1 | EARLY 0 | RANK #1916 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Advanced Colorectal Cancer (56% recruiting · 9 trials)
Appendicitis lists 5 open slots (56% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Appendicitis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Appendicitis is recruiting above its size-band peers.
5 of 9 indexed trials (55.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Appendicitis trials is spread across many organizations.
Children's Health accounts for 1 of 9 trials (11.1%). 9 distinct sponsors appear on at least one study for this condition label.
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Typical Appendicitis enrolment sits around 178 participants.
Median target enrolment is 178 among the 9 trials that report a genuine target (sentinel values excluded). 3 of those (33.3%) plan for fewer than 100 participants.
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Appendicitis research is mostly interventional.
7 interventional and 2 observational studies make up this index (77.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
9 total, page 1 of 1
PAINED: Project Addressing INequities in the Emergency Department
Children's National Research Institute
NCT05488080
Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients
Ann & Robert H Lurie Children's Hospital of Chicago
NCT06395636
Operative Versus Non-Operative Management for Appendicitis With Abscess or Phlegmon
Yale University
NCT04168866
Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF
University of California, San Francisco
NCT05966454
Complex and Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX)
University of Louisville
NCT05838248
TICAP - Titanium Clips for Appendiceal Stump Closure
Aesculap
NCT01734837
Pediatric Appendicitis Pathway Study
Oregon Health and Science University
NCT01192620
Probiotics and Antibiotic Associated Diarrhea in Pediatric Complicated Appendicitis
Children's Health
NCT04529980
Single Incision Laparoscopy
University of California, San Diego
NCT00616616
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Appendicitis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Appendicitis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Appendicitis page
9 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Appendicitis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Children's Health sponsors the most Appendicitis trials on record, review their full trial history before evaluating a specific study. See Children's Health's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Appendicitis condition card totals 9 registered trials; most-linked intervention single incision laparoscopic surgery; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.