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NCT05838248 · ClinicalTrials.gov registry record · NA
Complex and Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX)
A NA study of Appendicitis, sponsored by University of Louisville.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 2
- Study locations
NCT05838248 is a NA study of Appendicitis that is actively recruiting participants, run by University of Louisville. The registered enrollment target is 50 participants, below the 2,943-participant average among 8 other Appendicitis trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT05838248, a NA study of Appendicitis, is actively recruiting participants, sponsored by University of Louisville.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 2
- Study locations
Study Summary
This prospective trial will randomize patients who have had an appendectomy to two different durations of antibiotic therapy depending on the status of the appendicitis. For simple appendicitis, patients will be randomized to peri-operative antibiotics or 24 hours duration. For complex appendicitis, patients will be randomized to 24 hours or 4 days duration. Data will be collected prospectively and test the hypothesis that shorter durations of antibiotics will be non-inferior to the longer durations.
Conditions Studied
Interventions
- OTHER antibiotic duration
Study Locations (2)
Kentucky
- Jewish Hospital UL - Louisville
- University of Louisville Hospital - Louisville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-01-24 |
| Est. Completion | 2026-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05838248
The ClinicalTrials.gov registry entry for NCT05838248 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,943-participant average among 8 other Appendicitis trials with a reported enrollment target (98% lower). The listed sponsor is University of Louisville, which has 217 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Appendicitis appearing as the primary indexed condition, and to 1 intervention - of which antibiotic duration is the first listed.
NCT05838248 reports 2 study locations spanning 1 distinct geographic area - top geographies include Kentucky.
Frequently Asked Questions
What is clinical trial NCT05838248 about?
NCT05838248 is a clinical study titled "Complex and Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX)". This prospective trial will randomize patients who have had an appendectomy to two different durations of antibiotic therapy depending on the status of the appendicitis. For simple appendicitis, patients will be randomized to peri-operative antibiotics or 24 hours duration. For complex appendicitis,...
What is the current status of trial NCT05838248?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2023-01-24. Estimated completion is 2026-06.
What conditions does trial NCT05838248 study?
This clinical trial studies the following conditions: Appendicitis.
What interventions are being tested in trial NCT05838248?
The interventions under investigation include: antibiotic duration (OTHER).
Who is sponsoring clinical trial NCT05838248?
This trial is sponsored by University of Louisville, which has 217 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05838248 being conducted?
This trial has 2 study locations across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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