Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01734837 · ClinicalTrials.gov registry record

TICAP - Titanium Clips for Appendiceal Stump Closure

A clinical trial of Appendicitis, sponsored by Aesculap.

Completed
Registry status
390
Enrollment target
9
Study locations

NCT01734837: Completed study of Appendicitis, sponsored by Aesculap.

NCT01734837 is a study of Appendicitis that has completed, run by Aesculap. The registered enrollment target is 390 participants, below the 2,901-participant average among 8 other Appendicitis trials with a reported enrollment target (87% lower). The trial reports 9 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01734837, a study of Appendicitis, has completed, sponsored by Aesculap.

COMPLETED
Registry status
390 participants
Enrollment target
9
Study locations

Study Summary

Laparoscopic appendectomy is progressively accepted as the treatment of choice for acute appendicitis. Although the surgical technique of laparoscopic appendectomy has been well established, some controversy exists regarding the closure of the appendiceal stump. The available methods for stump closure are currently: pre-knotted loops (Roeder Loops or Endoloop, linear stapler and polymeric clips. A new device is a the DS Titanium Ligation Clip. The design of the DS-Clip is characterized by two parallel shanks. The aim of this study is to collect data of a large number of patients treated with the product in real-life clinical routine.

Primary Outcome

Documentation of the number of successful (= completed stump closure) versus non-successful (= clip could not be applied) applications of the DS-Clip

Conditions Studied

Interventions

  • DEVICE DS-Ligature Clip

Study Locations (9)

Other

  • Vivantes Humboldt-Klinikum - Berlin
  • DRK Krankenhaus Clementinen - Hanover
  • University of Mainz, Department of Surgery - Mainz
  • Universitätsklinikum Mannheim - Mannheim
  • Klinikum Memmingen - Memmingen
  • Katharinenhospital - Stuttgart
  • Schwarzwald-Baar Klinikum Villingen-Schwenningen GmbH - Villingen-Schwenningen

California

  • Marina del Rey Hospital - Marina del Rey

Pennsylvania

  • St. Luke's University Hospital - Bethlehem

Trial Details

FieldValue
Enrollment Target 390 participants
Start Date 2011-10
Est. Completion 2013-08
Aesculap

2 total trials

What the finished NCT01734837 record still lists

NCT01734837 is an observational study that tracks outcomes without assigning an intervention. The registered 390 participants enrollment target is mid-sized for trials with a published cap, below the 2,901-participant average among 8 other Appendicitis trials with a reported enrollment target (87% lower).

The record links to 1 condition, with Appendicitis appearing as the primary indexed condition, and to 1 intervention - of which DS-Ligature Clip is the first listed.

NCT01734837 lists 9 locations in 3 states (Other, California, Pennsylvania).

Frequently Asked Questions

What is clinical trial NCT01734837 about?

NCT01734837 is a clinical study titled "TICAP - Titanium Clips for Appendiceal Stump Closure". Laparoscopic appendectomy is progressively accepted as the treatment of choice for acute appendicitis. Although the surgical technique of laparoscopic appendectomy has been well established, some controversy exists regarding the closure of the appendiceal stump. The available methods for stump closu...

What is the current status of trial NCT01734837?

This trial is currently completed. The enrollment target is 390 participants. The study started on 2011-10. Estimated completion is 2013-08.

What conditions does trial NCT01734837 study?

This clinical trial studies the following conditions: Appendicitis.

What interventions are being tested in trial NCT01734837?

The interventions under investigation include: DS-Ligature Clip (DEVICE).

Who is sponsoring clinical trial NCT01734837?

This trial is sponsored by Aesculap, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01734837 being conducted?

This trial has 9 study locations across California, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Appendicitis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01734837's enrollment target sits among peer trials

390 3rd of 8 higher than 6 of 8 other Appendicitis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Appendicitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00397111 · 390 participants

    Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders

  • NCT05335928 · 390 participants · Phase 3

    Abatacept in Immune Checkpoint Inhibitor Myocarditis

  • NCT05445960 · 390 participants · NA

    Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery

  • NCT05997615 · 390 participants · Phase 1

    Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01734837, the US trial registry maintained by the National Library of Medicine. NCT01734837 (mid enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.