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NCT05966454 · ClinicalTrials.gov registry record · Phase 4
Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF
A Phase 4 study of Appendicitis, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 145
- Enrollment target
- 1
- Study location
NCT05966454: Recruiting Phase 4 study of Appendicitis, sponsored by University of California, San Francisco.
NCT05966454 is a Phase 4 study of Appendicitis that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 145 participants, below the 2,932-participant average among 8 other Appendicitis trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05966454, a Phase 4 study of Appendicitis, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 145 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to demonstrate the safety, efficacy, and feasibility of short-course post-operative antibiotic treatment for simple and complicated appendicitis
Primary Outcome
Infectious/antibiotic complication requiring antibiotic treatment only, Emergency Department visit, hospital readmission, percutaneous drainage, and operative intervention as assessed by treating physician.
Conditions Studied
Interventions
- DRUG Multiple standard of care antibiotics for appendicitis, at physicians' discretion
Study Locations (1)
California
- Zuckerberg San Francisco General Hospital - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 145 participants |
| Start Date | 2023-06-06 |
| Est. Completion | 2026-06-30 |
| Phase | Phase 4 |
What NCT05966454 shows while recruiting
NCT05966454 is an interventional study that assigns participants to a tested intervention. The registered 145 participants enrollment target is mid-sized for trials with a published cap, below the 2,932-participant average among 8 other Appendicitis trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Appendicitis appearing as the primary indexed condition, and to 1 intervention - of which Multiple standard of care antibiotics for appendicitis, at physicians' discretion is the first listed.
NCT05966454 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05966454 about?
NCT05966454 is a clinical study titled "Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF". The purpose of this study is to demonstrate the safety, efficacy, and feasibility of short-course post-operative antibiotic treatment for simple and complicated appendicitis
What is the current status of trial NCT05966454?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 145 participants. The study started on 2023-06-06. Estimated completion is 2026-06-30.
What conditions does trial NCT05966454 study?
This clinical trial studies the following conditions: Appendicitis.
What interventions are being tested in trial NCT05966454?
The interventions under investigation include: Multiple standard of care antibiotics for appendicitis, at physicians' discretion (DRUG).
Who is sponsoring clinical trial NCT05966454?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05966454 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Appendicitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05966454's enrollment target sits among peer trials
145 6th of 8 higher than 3 of 8 other Appendicitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Appendicitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Operative Versus Non-Operative Management for Appendicitis With Abscess or Phlegmon
RECRUITING · NA
-
Complex and Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX)
RECRUITING · NA
-
PAINED: Project Addressing INequities in the Emergency Department
RECRUITING · NA
-
Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients
RECRUITING · NA
-
Pediatric Appendicitis Pathway Study
COMPLETED
-
TICAP - Titanium Clips for Appendiceal Stump Closure
COMPLETED
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