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ClinicalTrials.gov 148 recruiting now early-phase tilt #17 of 28,707 conditions

Anxiety: early-phase trial registry

148 of 367 indexed Anxiety trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #17 of 28,707 conditions by registered trial count.

367 US clinical trials · 148 currently recruiting · #17 of 28,707 conditions by registered trial count

Anxiety: 367 US clinical trials tracked, 148 recruiting.

Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.

Enrollment posture brief

Registry condition anxiety

OPEN 148 | RECR 40% | LATE 15 | EARLY 38 | RANK #17 | SPON 11

Nearest open-share peer: Pain, Postoperative (40% recruiting · 114 trials)

Anxiety (this)40%Pain28.1%Diabetes25.1%Asthma18.5%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Anxiety

Anxiety lists 148 open slots (40% of 367 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anxiety on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anxiety is recruiting above its size-band peers.

    148 of 367 indexed trials (40.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Anxiety trials is spread across many organizations.

    University of California, Los Angeles accounts for 11 of 367 trials (3%). 191 distinct sponsors appear on at least one study for this condition label.

  3. Typical Anxiety enrolment sits around 95 participants.

    Median target enrolment is 95 among the 365 trials that report a genuine target (sentinel values excluded). 188 of those (51.5%) plan for fewer than 100 participants.

  4. Anxiety research is mostly interventional.

    339 interventional and 28 observational studies make up this index (92.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 113Phase 225Phase 36Phase 49

Open and recent trials

367 total, page 6 of 8

COMPLETED Phase 4 120 participants

Disentangling Anxiety Sensitivity and Anxiety-induced Physiological Stress Response

University of Texas at Austin

NCT02372110

COMPLETED NA 119 participants

Neuroplasticity in an Extended Amygdala Network as a Target Mechanism for Attention Bias Modification Outcome

Northern Michigan University

NCT03092609

COMPLETED NA 117 participants

IntelliCare in College Students - Implementation (ICCS-I)

Northwestern University

NCT04108429

COMPLETED Phase 4 114 participants

Randomized Control Trial of a Topical Anesthetic to Evaluate Pain and Anxiety During Venipuncture

Jenny Boucher, PharmD

NCT00676364

COMPLETED NA 111 participants

Assessing the Impact of LIve Music in the Intensive Care Unit (ICU) to Improve Care for Critically Ill Patients

Vanderbilt University Medical Center

NCT03948984

COMPLETED NA 110 participants

Family-Focused CBT Skills App and Standard Self Help Options for Childhood Anxiety

Kansas City Center for Anxiety Treatment, P.A.

NCT03269370

COMPLETED NA 108 participants

Cognitive Anxiety Sensitivity Treatment for Suicide

Florida State University

NCT01947179

COMPLETED NA 108 participants

Does Conscious Connected Breathwork Reduce Symptoms of Anxiety?

Richard Blake

NCT06374810

COMPLETED NA 106 participants

Pilot Trial of a Social Skills Group Treatment (Secret Agent Society Program)

Weill Medical College of Cornell University

NCT02574273

COMPLETED NA 102 participants

A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers

Duke University

NCT04816708

COMPLETED NA 100 participants

Using Neuroimaging to Understand Children's Mental Health and Treatment Outcomes

Harvard University

NCT03112265

COMPLETED NA 100 participants

Effectiveness of External Vibration for Pain Relief During Intravenous Access in Adult Patients

Kyle Stein

NCT03619135

COMPLETED 100 participants

Caregiver Burden and Distress in Hematopoeitic Stem Cell Transplant

Northside Hospital

NCT01084694

COMPLETED NA 100 participants

Music and Local Anesthesia During Dermatologic Procedures

Washington University School of Medicine

NCT04317170

COMPLETED NA 100 participants

Assessing Patient Anxiety During Mohs Micrographic Surgery

Wake Forest University Health Sciences

NCT03756792

COMPLETED NA 96 participants

Controlled Substance Treatment Agreements in an Internal Medicine Residents' Clinic

Ohio State University

NCT02244099

COMPLETED NA 96 participants

Music to Reduce Patient Reported Pain During Intrauterine Device (IUD) Placement in the Office

Rutgers, The State University of New Jersey

NCT05068245

COMPLETED NA 95 participants

Qualitative Sweat Distribution During Tilt Table Procedure

Nationwide Children's Hospital

NCT02329548

COMPLETED NA 95 participants

Personalized Feedback for Smokers With Elevated Anxiety Sensitivity

University of Houston

NCT03382093

COMPLETED NA 89 participants

Radiation Oncology Patient Medical Physics Intervention Study

The University of Texas Health Science Center at San Antonio

NCT04362306

COMPLETED NA 86 participants

A Mobile Health Solution for Homework During CBT

University of South Florida

NCT04931199

COMPLETED NA 85 participants

Bio-Experiential Spaces for Mental Health in Healthworkers

Icahn School of Medicine at Mount Sinai

NCT05227352

COMPLETED NA 83 participants

The Effect of Psychotherapy on Stress Biochemistry: An RCT of Psychotherapy and Emotional Freedom Techniques (EFT)

Soul Medicine Institute

NCT00641394

COMPLETED Phase 2 81 participants

Anxiety and Recurrent Abdominal Pain in Children

John V. Campo, M.D.

NCT00962039

COMPLETED NA 80 participants

Lavender Aromatherapy for Anxiety During Urodynamics

University of Southern California

NCT02344745

COMPLETED NA 80 participants

Music Therapy in the Treatment of Perioperative Anxiety and Pain

University of Pittsburgh

NCT05263635

COMPLETED NA 75 participants

Safety and Efficacy of Oral Midazolam for Perioperative Anxiety Relief of Patients Undergoing Mohs Micrographic Surgery

Mayo Clinic

NCT00578214

COMPLETED NA 75 participants

A Randomized-Controlled Trial to Investigate the Effect of a Novel Music Therapy Application to Reduce Anxiety and Stress

SoundMind

NCT06021821

COMPLETED NA 74 participants

Computerized Anxiety Treatment for Suicide

Florida State University

NCT01990131

COMPLETED NA 73 participants

Reducing Anxiety Levels Through the Dharma Life App-Based and Mentor-Based Program Targeting Personality Characteristics: A Randomized Control Trial

Dharma Life Sciences

NCT06138652

COMPLETED NA 72 participants

Does Treating Anxiety Symptoms With ACT Improve Vascular Inflammation and Function?

University of Iowa

NCT02915874

COMPLETED NA 71 participants

Perioperative Virtual Reality for Pediatric Anesthesia

University of California, San Francisco

NCT03583450

COMPLETED NA 71 participants

Effectiveness of a Unified Transdiagnostic Treatment in Routine Care

Boston University

NCT02944994

COMPLETED 71 participants

Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic

University of Florida

NCT02855580

COMPLETED NA 70 participants

Meditation for NICU Moms

St. Louis University

NCT03574766

COMPLETED NA 68 participants

Effect of rTMS on Anxiety

University of Pennsylvania

NCT03993509

COMPLETED Phase 2 68 participants

Specifying and Treating Anxiety in Autism Research

University of California, Davis

NCT03279471

COMPLETED NA 68 participants

Stepped-Care Telehealth for Distress in Cancer Survivors

Wake Forest University Health Sciences

NCT03060096

COMPLETED NA 66 participants

Trial of Asthma Self-Management Education in Patients With Depressive Symptoms

Hospital for Special Surgery, New York

NCT01708070

COMPLETED 66 participants

Anxiety and Reward Interaction and Prediction of Outcomes in Anorexia Nervosa

University of California, Los Angeles

NCT02948452

COMPLETED NA 64 participants

Effects of Open-label Placebos on COVID-related Psychological Health

Michigan State University

NCT05035550

COMPLETED NA 64 participants

Mindfulness, Yoga, and Cardiovascular Disease

The Cleveland Clinic

NCT00696852

COMPLETED NA 63 participants

Study of a PST-Trained Voice-Enabled Artificial Intelligence Counselor (SPEAC) for Adults With Emotional Distress (Phase 1)

University of Illinois at Chicago

NCT04524104

COMPLETED NA 60 participants

Preventing Depression and Anxiety: A Cystic Fibrosis-Specific Cognitive Behavioral Therapy Intervention

Massachusetts General Hospital

NCT03992027

COMPLETED NA 60 participants

The Effects of Lavender Aromatherapy on Reducing Stress and Anxiety During MRI Procedures.

Allina Health System

NCT01809067

COMPLETED NA 57 participants

The Treatment of Depression With Yoga and Walking

Boston University

NCT02907476

COMPLETED Phase 1 56 participants

The Effects of Smell on Mood and Physical Responses

National Center for Complementary and Integrative Health (NCCIH)

NCT00097253

COMPLETED NA 51 participants

Preoperative 3D Models and Shared Decision-making

Vanderbilt University Medical Center

NCT06625008

COMPLETED NA 50 participants

Live Video Mind-body Treatment to Prevent Persistent Symptoms Following mTBI

Massachusetts General Hospital

NCT05524402

COMPLETED NA 50 participants

Comparing Acceptance and Commitment Therapy (ACT) and Cognitive Therapy (CT) for Test Anxiety

Drexel University

NCT00850226

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 25
Phase 3 6
Phase 4 9

Named interventions

Most-linked intervention names on Anxiety records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
13 trials
Placebo Other
7 trials
Music Other
4 trials
Yoga Behavioral
3 trials
Psilocybin Drug
3 trials
Cognitive Behavioral Therapy (CBT) Behavioral
3 trials
IDgenetix Neuropsychiatric Test Panel Genetic
2 trials
Emotion Regulation Therapy via Telehealth Behavioral
2 trials

US sites by state

Facility locations filed on Anxiety trials. A trial with sites in several states counts in each.

California 58 trials
New York 38 trials
Massachusetts 30 trials
Texas 27 trials
Florida 27 trials
Pennsylvania 24 trials
North Carolina 22 trials
Ohio 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anxiety page

367 registered trials, 148 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anxiety condition card totals 367 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.