Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Anxiety clinical trials
148 of 367 indexed Anxiety trials are currently recruiting.
367 US clinical trials · 148 currently recruiting
Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.
The research picture
Anxiety has 367 registered US clinical trials, 148 of them open to new participants right now, about 40% of the total.
- 148
- recruiting participants now
- 40%
- of trials open to enrollment
- 15
- in Phase 3–4 (later-stage)
- 11
- top sponsor: University of California, Los Angeles
Active & Recent Trials
367 total, page 6 of 8
Disentangling Anxiety Sensitivity and Anxiety-induced Physiological Stress Response
University of Texas at Austin
NCT02372110
Neuroplasticity in an Extended Amygdala Network as a Target Mechanism for Attention Bias Modification Outcome
Northern Michigan University
NCT03092609
IntelliCare in College Students - Implementation (ICCS-I)
Northwestern University
NCT04108429
Randomized Control Trial of a Topical Anesthetic to Evaluate Pain and Anxiety During Venipuncture
Jenny Boucher, PharmD
NCT00676364
Assessing the Impact of LIve Music in the Intensive Care Unit (ICU) to Improve Care for Critically Ill Patients
Vanderbilt University Medical Center
NCT03948984
Family-Focused CBT Skills App and Standard Self Help Options for Childhood Anxiety
Kansas City Center for Anxiety Treatment, P.A.
NCT03269370
Cognitive Anxiety Sensitivity Treatment for Suicide
Florida State University
NCT01947179
Does Conscious Connected Breathwork Reduce Symptoms of Anxiety?
Richard Blake
NCT06374810
Pilot Trial of a Social Skills Group Treatment (Secret Agent Society Program)
Weill Medical College of Cornell University
NCT02574273
A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers
Duke University
NCT04816708
Using Neuroimaging to Understand Children's Mental Health and Treatment Outcomes
Harvard University
NCT03112265
Effectiveness of External Vibration for Pain Relief During Intravenous Access in Adult Patients
Kyle Stein
NCT03619135
Caregiver Burden and Distress in Hematopoeitic Stem Cell Transplant
Northside Hospital
NCT01084694
Music and Local Anesthesia During Dermatologic Procedures
Washington University School of Medicine
NCT04317170
Assessing Patient Anxiety During Mohs Micrographic Surgery
Wake Forest University Health Sciences
NCT03756792
Controlled Substance Treatment Agreements in an Internal Medicine Residents' Clinic
Ohio State University
NCT02244099
Music to Reduce Patient Reported Pain During Intrauterine Device (IUD) Placement in the Office
Rutgers, The State University of New Jersey
NCT05068245
Qualitative Sweat Distribution During Tilt Table Procedure
Nationwide Children's Hospital
NCT02329548
Personalized Feedback for Smokers With Elevated Anxiety Sensitivity
University of Houston
NCT03382093
Radiation Oncology Patient Medical Physics Intervention Study
The University of Texas Health Science Center at San Antonio
NCT04362306
A Mobile Health Solution for Homework During CBT
University of South Florida
NCT04931199
Bio-Experiential Spaces for Mental Health in Healthworkers
Icahn School of Medicine at Mount Sinai
NCT05227352
The Effect of Psychotherapy on Stress Biochemistry: An RCT of Psychotherapy and Emotional Freedom Techniques (EFT)
Soul Medicine Institute
NCT00641394
Anxiety and Recurrent Abdominal Pain in Children
John V. Campo, M.D.
NCT00962039
Lavender Aromatherapy for Anxiety During Urodynamics
University of Southern California
NCT02344745
Music Therapy in the Treatment of Perioperative Anxiety and Pain
University of Pittsburgh
NCT05263635
Safety and Efficacy of Oral Midazolam for Perioperative Anxiety Relief of Patients Undergoing Mohs Micrographic Surgery
Mayo Clinic
NCT00578214
A Randomized-Controlled Trial to Investigate the Effect of a Novel Music Therapy Application to Reduce Anxiety and Stress
SoundMind
NCT06021821
Computerized Anxiety Treatment for Suicide
Florida State University
NCT01990131
Reducing Anxiety Levels Through the Dharma Life App-Based and Mentor-Based Program Targeting Personality Characteristics: A Randomized Control Trial
Dharma Life Sciences
NCT06138652
Does Treating Anxiety Symptoms With ACT Improve Vascular Inflammation and Function?
University of Iowa
NCT02915874
Perioperative Virtual Reality for Pediatric Anesthesia
University of California, San Francisco
NCT03583450
Effectiveness of a Unified Transdiagnostic Treatment in Routine Care
Boston University
NCT02944994
Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic
University of Florida
NCT02855580
Meditation for NICU Moms
St. Louis University
NCT03574766
Effect of rTMS on Anxiety
University of Pennsylvania
NCT03993509
Specifying and Treating Anxiety in Autism Research
University of California, Davis
NCT03279471
Stepped-Care Telehealth for Distress in Cancer Survivors
Wake Forest University Health Sciences
NCT03060096
Trial of Asthma Self-Management Education in Patients With Depressive Symptoms
Hospital for Special Surgery, New York
NCT01708070
Anxiety and Reward Interaction and Prediction of Outcomes in Anorexia Nervosa
University of California, Los Angeles
NCT02948452
Effects of Open-label Placebos on COVID-related Psychological Health
Michigan State University
NCT05035550
Mindfulness, Yoga, and Cardiovascular Disease
The Cleveland Clinic
NCT00696852
Study of a PST-Trained Voice-Enabled Artificial Intelligence Counselor (SPEAC) for Adults With Emotional Distress (Phase 1)
University of Illinois at Chicago
NCT04524104
Preventing Depression and Anxiety: A Cystic Fibrosis-Specific Cognitive Behavioral Therapy Intervention
Massachusetts General Hospital
NCT03992027
The Effects of Lavender Aromatherapy on Reducing Stress and Anxiety During MRI Procedures.
Allina Health System
NCT01809067
The Treatment of Depression With Yoga and Walking
Boston University
NCT02907476
The Effects of Smell on Mood and Physical Responses
National Center for Complementary and Integrative Health (NCCIH)
NCT00097253
Preoperative 3D Models and Shared Decision-making
Vanderbilt University Medical Center
NCT06625008
Live Video Mind-body Treatment to Prevent Persistent Symptoms Following mTBI
Massachusetts General Hospital
NCT05524402
Comparing Acceptance and Commitment Therapy (ACT) and Cognitive Therapy (CT) for Test Anxiety
Drexel University
NCT00850226
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 25 |
| Phase 3 | 6 |
| Phase 4 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Anxiety Trial Landscape
367 indexed Anxiety studies · 148 recruiting (40%).
Phase mix: 15 late (III/IV) vs 38 early (I/II).
Top sponsor: University of California, Los Angeles (11 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Anxiety?
PlainTrial tracks 367 US clinical trials for Anxiety, of which 148 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Anxiety?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.