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ClinicalTrials.gov 148 recruiting now early-phase tilt #17 of 28,707 conditions

Anxiety: early-phase trial registry

148 of 367 indexed Anxiety trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #17 of 28,707 conditions by registered trial count.

367 US clinical trials · 148 currently recruiting · #17 of 28,707 conditions by registered trial count

Anxiety: 367 US clinical trials tracked, 148 recruiting.

Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.

Enrollment posture brief

Registry condition anxiety

OPEN 148 | RECR 40% | LATE 15 | EARLY 38 | RANK #17 | SPON 11

Nearest open-share peer: Pain, Postoperative (40% recruiting · 114 trials)

Anxiety (this)40%Pain28.1%Diabetes25.1%Asthma18.5%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Anxiety

Anxiety lists 148 open slots (40% of 367 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anxiety on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anxiety is recruiting above its size-band peers.

    148 of 367 indexed trials (40.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Anxiety trials is spread across many organizations.

    University of California, Los Angeles accounts for 11 of 367 trials (3%). 191 distinct sponsors appear on at least one study for this condition label.

  3. Typical Anxiety enrolment sits around 95 participants.

    Median target enrolment is 95 among the 365 trials that report a genuine target (sentinel values excluded). 188 of those (51.5%) plan for fewer than 100 participants.

  4. Anxiety research is mostly interventional.

    339 interventional and 28 observational studies make up this index (92.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 113Phase 225Phase 36Phase 49

Open and recent trials

367 total, page 7 of 8

COMPLETED NA 50 participants

Hypnosis-Based Machine Learning Biomarker Study

Icahn School of Medicine at Mount Sinai

NCT07102810

COMPLETED NA 49 participants

Neural Mechanisms of Treatment Response to ADAPT

Michigan State University

NCT03518216

COMPLETED Phase 2 48 participants

Use of an Antibiotic as an Enhancer for the Treatment of Social Phobia

National Institute of Mental Health (NIMH)

NCT00128401

COMPLETED NA 46 participants

The Effect of Touch on Pain and Anxiety During the Bone Marrow Biopsy Procedure

Dartmouth-Hitchcock Medical Center

NCT04935775

COMPLETED NA 45 participants

The Effects of the Safe and Sound Protocol on PTSD Symptoms and Anxiety

Indiana University

NCT04999852

COMPLETED NA 44 participants

Stay Connected: Testing an Intervention to Combat Coronavirus-related Social Isolation Among Older Adults

University of Washington

NCT04966910

COMPLETED NA 44 participants

Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health

University of Alaska Anchorage

NCT04561544

COMPLETED NA 43 participants

Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment

Massachusetts General Hospital

NCT02447744

COMPLETED 41 participants

The Impact of Therapy Dogs on Anxiety and Emotional Management in the Pediatric Emergency Department

University of Louisville

NCT04942678

COMPLETED NA 40 participants

Pilot Trial of Hypnosis and Enhanced Communication In Patients Undergoing MRI

University of Colorado, Denver

NCT04520100

COMPLETED NA 40 participants

Care Outcomes for Chiropractic Outpatient Veterans

Palmer College of Chiropractic

NCT03254719

COMPLETED 40 participants

Virtual Reality in Plastic Surgery: Pain Control and Augmented Satisfaction

The Guthrie Clinic

NCT03914937

COMPLETED NA 40 participants

Using Smartphones to Enhance the Treatment of Childhood Anxiety

University of Pittsburgh

NCT02259036

COMPLETED NA 40 participants

Sequential Allocation Study of Music Duration

Tufts Medical Center

NCT04909736

COMPLETED NA 40 participants

Trial to Test Effectiveness of Depression Intervention for Mistreated Older Adults

Weill Medical College of Cornell University

NCT04258579

COMPLETED NA 40 participants

Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD

Mayo Clinic

NCT02713516

COMPLETED NA 38 participants

Mindfulness-Music Intervention for Adolescents and Young Adults With Cancer

Dana-Farber Cancer Institute

NCT03709225

COMPLETED NA 38 participants

Supporting Our Valued Adolescents Pilot Randomized Controlled Trial

University of Pittsburgh

NCT03318666

COMPLETED NA 38 participants

Improving Quality of Life for Veterans With Stroke and Psychological Distress

VA Office of Research and Development

NCT03645759

COMPLETED NA 37 participants

Mindfulness-Based Stress Reduction for Metro Nashville Public School Employees

Vanderbilt University Medical Center

NCT05051969

COMPLETED NA 35 participants

Study to Evaluate the Efficacy of Asystems' Complete Calm Supplementation on Sleep Quality and Duration, Anxiety, and Stress

Asystem

NCT05190640

COMPLETED NA 35 participants

Study to Evaluate the Efficacy of Arrae's Bloat & Calm Alchemy Capsules to Reduce Bloating, Heartburn and Gas, and Alleviate the Intensity of IBS Symptoms

Arrae

NCT05197413

COMPLETED NA 35 participants

Mindfulness Based Cognitive Therapy for Youth With Anxiety at Risk for Bipolar Disorder

University of Cincinnati

NCT02090595

COMPLETED NA 33 participants

WILD 5 Wellness, A 30-Day Intervention

Beloit College

NCT03328520

COMPLETED Phase 1 33 participants

Bright Light: A Novel Treatment for Anxiety

University of South Carolina

NCT01064700

COMPLETED Phase 1 33 participants

Enhancing Delivery of Problem Solving Therapy Using SmartPhone Technology

VA Office of Research and Development

NCT01891734

COMPLETED NA 32 participants

A Single-Arm, Virtual Clinical Trial to Evaluate the Effects of a Sleep Supporting Beverage and Two Coffee Substitute Products

Clevr Blends

NCT06146517

COMPLETED NA 32 participants

Utilization of Different Virtual Reality Experiences

Oregon Health and Science University

NCT04828980

COMPLETED Phase 2 31 participants

Sublingual Cannabidiol for Anxiety

Staci Gruber, Ph.D.

NCT02548559

COMPLETED NA 30 participants

Mindfulness for Breast Cancer

NYU Langone Health

NCT02647216

COMPLETED NA 30 participants

Cognitive Behavioral Therapy and Real-time Self-management Intervention for SCD Via Mobile Applications

University of Pittsburgh

NCT02384590

COMPLETED NA 29 participants

Patient Experiences With Virtual Reality Mindfulness Skills Training

Weill Medical College of Cornell University

NCT05291533

COMPLETED NA 28 participants

EEG Alpha/Theta Neurofeedback to Reduce Trait Anxiety

University of Hartford

NCT02964520

COMPLETED NA 27 participants

Strategies for Treating Anxiety Research Study

University of Nevada, Las Vegas

NCT05398016

COMPLETED NA 26 participants

UCSF TARA Study: Training for Awareness, Resilience and Action

University of California, San Francisco

NCT02480257

COMPLETED Phase 1 23 participants

Transforming Psychotherapy for Chronically Ill Patients

US Department of Veterans Affairs

NCT00520429

COMPLETED NA 23 participants

Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults

Vanderbilt University Medical Center

NCT06197243

COMPLETED Phase 2 21 participants

Buspirone in Parkinson's Disease

University of Rochester

NCT02803749

COMPLETED NA 21 participants

Effects of Virtual Reality MRI Preparedness

Children's Hospital Los Angeles

NCT05086263

COMPLETED Phase 1 20 participants

Patient-Controlled Anxiolysis With Dexmedetomidine (PCA-DEX) for Burn-care Dressing Changes

Ohio State University

NCT02409810

COMPLETED Phase 4 20 participants

Epidiolex® for Anxiety in Pediatric Epilepsy

Hugo W. Moser Research Institute at Kennedy Krieger

NCT05324449

COMPLETED NA 19 participants

Effects of a 2-week Relaxing Music Intervention on Anxiety, Stress, and Gut Symptoms in Aerobic Exercisers

Old Dominion University

NCT04671628

COMPLETED NA 19 participants

Tai Chi Easy for Opioid Use Disorder, Anxiety, and Chronic Pain

Asana Recovery

NCT05850533

COMPLETED NA 18 participants

Brief Cognitive Behavioral Therapy for Anxiety

Michael E. DeBakey VA Medical Center

NCT03820973

COMPLETED NA 18 participants

VA Home-Based Emotional Learning With Practical Skills

Baylor College of Medicine

NCT01685528

COMPLETED Phase 4 18 participants

Effects of Oxytocin on Behavior and Physiology in a Psychotherapy Setting

MacDonald, Kai, M.D.

NCT01081249

COMPLETED NA 18 participants

Parenting Young Children in Pediatrics

University of Oregon

NCT06273228

COMPLETED 18 participants

The Effect of Nasal Continuous Positive Airway Pressure Treatment on PTSD Symptoms.

Northport Veterans Affairs Medical Center

NCT01512771

COMPLETED NA 17 participants

Coaching Children With Anxiety and Autism Through Telehealth

Medical University of South Carolina

NCT05588570

COMPLETED NA 17 participants

Traditional African Healing Ceremony in a U.S. Population

Duke University

NCT01873482

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 25
Phase 3 6
Phase 4 9

Named interventions

Most-linked intervention names on Anxiety records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
13 trials
Placebo Other
7 trials
Music Other
4 trials
Yoga Behavioral
3 trials
Psilocybin Drug
3 trials
Cognitive Behavioral Therapy (CBT) Behavioral
3 trials
IDgenetix Neuropsychiatric Test Panel Genetic
2 trials
Emotion Regulation Therapy via Telehealth Behavioral
2 trials

US sites by state

Facility locations filed on Anxiety trials. A trial with sites in several states counts in each.

California 58 trials
New York 38 trials
Massachusetts 30 trials
Texas 27 trials
Florida 27 trials
Pennsylvania 24 trials
North Carolina 22 trials
Ohio 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anxiety page

367 registered trials, 148 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anxiety condition card totals 367 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.