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ClinicalTrials.gov 148 recruiting now official registry

Anxiety clinical trials

148 of 367 indexed Anxiety trials are currently recruiting.

367 US clinical trials · 148 currently recruiting

Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.

The research picture

Anxiety has 367 registered US clinical trials, 148 of them open to new participants right now, about 40% of the total.

148
recruiting participants now
40%
of trials open to enrollment
15
in Phase 3–4 (later-stage)
11
top sponsor: University of California, Los Angeles
Phase 113Phase 225Phase 36Phase 49

Active & Recent Trials

367 total, page 7 of 8

COMPLETED NA 50 participants

Hypnosis-Based Machine Learning Biomarker Study

Icahn School of Medicine at Mount Sinai

NCT07102810

COMPLETED NA 49 participants

Neural Mechanisms of Treatment Response to ADAPT

Michigan State University

NCT03518216

COMPLETED Phase 2 48 participants

Use of an Antibiotic as an Enhancer for the Treatment of Social Phobia

National Institute of Mental Health (NIMH)

NCT00128401

COMPLETED NA 46 participants

The Effect of Touch on Pain and Anxiety During the Bone Marrow Biopsy Procedure

Dartmouth-Hitchcock Medical Center

NCT04935775

COMPLETED NA 45 participants

The Effects of the Safe and Sound Protocol on PTSD Symptoms and Anxiety

Indiana University

NCT04999852

COMPLETED NA 44 participants

Stay Connected: Testing an Intervention to Combat Coronavirus-related Social Isolation Among Older Adults

University of Washington

NCT04966910

COMPLETED NA 44 participants

Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health

University of Alaska Anchorage

NCT04561544

COMPLETED NA 43 participants

Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment

Massachusetts General Hospital

NCT02447744

COMPLETED 41 participants

The Impact of Therapy Dogs on Anxiety and Emotional Management in the Pediatric Emergency Department

University of Louisville

NCT04942678

COMPLETED NA 40 participants

Pilot Trial of Hypnosis and Enhanced Communication In Patients Undergoing MRI

University of Colorado, Denver

NCT04520100

COMPLETED NA 40 participants

Care Outcomes for Chiropractic Outpatient Veterans

Palmer College of Chiropractic

NCT03254719

COMPLETED 40 participants

Virtual Reality in Plastic Surgery: Pain Control and Augmented Satisfaction

The Guthrie Clinic

NCT03914937

COMPLETED NA 40 participants

Using Smartphones to Enhance the Treatment of Childhood Anxiety

University of Pittsburgh

NCT02259036

COMPLETED NA 40 participants

Sequential Allocation Study of Music Duration

Tufts Medical Center

NCT04909736

COMPLETED NA 40 participants

Trial to Test Effectiveness of Depression Intervention for Mistreated Older Adults

Weill Medical College of Cornell University

NCT04258579

COMPLETED NA 40 participants

Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD

Mayo Clinic

NCT02713516

COMPLETED NA 38 participants

Mindfulness-Music Intervention for Adolescents and Young Adults With Cancer

Dana-Farber Cancer Institute

NCT03709225

COMPLETED NA 38 participants

Supporting Our Valued Adolescents Pilot Randomized Controlled Trial

University of Pittsburgh

NCT03318666

COMPLETED NA 38 participants

Improving Quality of Life for Veterans With Stroke and Psychological Distress

VA Office of Research and Development

NCT03645759

COMPLETED NA 37 participants

Mindfulness-Based Stress Reduction for Metro Nashville Public School Employees

Vanderbilt University Medical Center

NCT05051969

COMPLETED NA 35 participants

Study to Evaluate the Efficacy of Asystems' Complete Calm Supplementation on Sleep Quality and Duration, Anxiety, and Stress

Asystem

NCT05190640

COMPLETED NA 35 participants

Study to Evaluate the Efficacy of Arrae's Bloat & Calm Alchemy Capsules to Reduce Bloating, Heartburn and Gas, and Alleviate the Intensity of IBS Symptoms

Arrae

NCT05197413

COMPLETED NA 35 participants

Mindfulness Based Cognitive Therapy for Youth With Anxiety at Risk for Bipolar Disorder

University of Cincinnati

NCT02090595

COMPLETED NA 33 participants

WILD 5 Wellness, A 30-Day Intervention

Beloit College

NCT03328520

COMPLETED Phase 1 33 participants

Bright Light: A Novel Treatment for Anxiety

University of South Carolina

NCT01064700

COMPLETED Phase 1 33 participants

Enhancing Delivery of Problem Solving Therapy Using SmartPhone Technology

VA Office of Research and Development

NCT01891734

COMPLETED NA 32 participants

A Single-Arm, Virtual Clinical Trial to Evaluate the Effects of a Sleep Supporting Beverage and Two Coffee Substitute Products

Clevr Blends

NCT06146517

COMPLETED NA 32 participants

Utilization of Different Virtual Reality Experiences

Oregon Health and Science University

NCT04828980

COMPLETED Phase 2 31 participants

Sublingual Cannabidiol for Anxiety

Staci Gruber, Ph.D.

NCT02548559

COMPLETED NA 30 participants

Mindfulness for Breast Cancer

NYU Langone Health

NCT02647216

COMPLETED NA 30 participants

Cognitive Behavioral Therapy and Real-time Self-management Intervention for SCD Via Mobile Applications

University of Pittsburgh

NCT02384590

COMPLETED NA 29 participants

Patient Experiences With Virtual Reality Mindfulness Skills Training

Weill Medical College of Cornell University

NCT05291533

COMPLETED NA 28 participants

EEG Alpha/Theta Neurofeedback to Reduce Trait Anxiety

University of Hartford

NCT02964520

COMPLETED NA 27 participants

Strategies for Treating Anxiety Research Study

University of Nevada, Las Vegas

NCT05398016

COMPLETED NA 26 participants

UCSF TARA Study: Training for Awareness, Resilience and Action

University of California, San Francisco

NCT02480257

COMPLETED Phase 1 23 participants

Transforming Psychotherapy for Chronically Ill Patients

US Department of Veterans Affairs

NCT00520429

COMPLETED NA 23 participants

Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults

Vanderbilt University Medical Center

NCT06197243

COMPLETED Phase 2 21 participants

Buspirone in Parkinson's Disease

University of Rochester

NCT02803749

COMPLETED NA 21 participants

Effects of Virtual Reality MRI Preparedness

Children's Hospital Los Angeles

NCT05086263

COMPLETED Phase 1 20 participants

Patient-Controlled Anxiolysis With Dexmedetomidine (PCA-DEX) for Burn-care Dressing Changes

Ohio State University

NCT02409810

COMPLETED Phase 4 20 participants

Epidiolex® for Anxiety in Pediatric Epilepsy

Hugo W. Moser Research Institute at Kennedy Krieger

NCT05324449

COMPLETED NA 19 participants

Effects of a 2-week Relaxing Music Intervention on Anxiety, Stress, and Gut Symptoms in Aerobic Exercisers

Old Dominion University

NCT04671628

COMPLETED NA 19 participants

Tai Chi Easy for Opioid Use Disorder, Anxiety, and Chronic Pain

Asana Recovery

NCT05850533

COMPLETED NA 18 participants

Brief Cognitive Behavioral Therapy for Anxiety

Michael E. DeBakey VA Medical Center

NCT03820973

COMPLETED NA 18 participants

VA Home-Based Emotional Learning With Practical Skills

Baylor College of Medicine

NCT01685528

COMPLETED Phase 4 18 participants

Effects of Oxytocin on Behavior and Physiology in a Psychotherapy Setting

MacDonald, Kai, M.D.

NCT01081249

COMPLETED NA 18 participants

Parenting Young Children in Pediatrics

University of Oregon

NCT06273228

COMPLETED 18 participants

The Effect of Nasal Continuous Positive Airway Pressure Treatment on PTSD Symptoms.

Northport Veterans Affairs Medical Center

NCT01512771

COMPLETED NA 17 participants

Coaching Children With Anxiety and Autism Through Telehealth

Medical University of South Carolina

NCT05588570

COMPLETED NA 17 participants

Traditional African Healing Ceremony in a U.S. Population

Duke University

NCT01873482

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 25
Phase 3 6
Phase 4 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Anxiety Trial Landscape

367 indexed Anxiety studies · 148 recruiting (40%).

Phase mix: 15 late (III/IV) vs 38 early (I/II).

Top sponsor: University of California, Los Angeles (11 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Anxiety?

PlainTrial tracks 367 US clinical trials for Anxiety, of which 148 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Anxiety?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.