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Amyotrophic Lateral Sclerosis: early-phase trial registry
47 of 103 indexed Amyotrophic Lateral Sclerosis trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #130 of 28,707 conditions by registered trial count.
103 US clinical trials · 47 currently recruiting · #130 of 28,707 conditions by registered trial count
Amyotrophic Lateral Sclerosis: 103 US clinical trials tracked, 47 recruiting.
Amyotrophic Lateral Sclerosis is the subject of 103 registered US clinical trials on ClinicalTrials.gov, 47 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 40 in Phase 1-2 (earlier-stage). The most active sponsor is University of Miami, running 7 of these trials.
Enrollment posture brief
Registry condition amyotrophic-lateral-sclerosis
OPEN 47 | RECR 46% | LATE 6 | EARLY 40 | RANK #130 | SPON 7
Volume-matched condition peers
Nearest open-share peer: Endothelial Dysfunction (46% recruiting · 46 trials)
Amyotrophic Lateral Sclerosis lists 47 open slots (46% of 103 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Amyotrophic Lateral Sclerosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Amyotrophic Lateral Sclerosis is recruiting above its size-band peers.
47 of 103 indexed trials (45.6%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Amyotrophic Lateral Sclerosis trials is spread across many organizations.
University of Miami accounts for 7 of 103 trials (6.8%). 69 distinct sponsors appear on at least one study for this condition label.
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Most Amyotrophic Lateral Sclerosis trials plan to enrol fewer than 100 people.
Median target enrolment is 66 among the 103 trials that report a genuine target (sentinel values excluded). 62 of those (60.2%) plan for fewer than 100 participants.
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Amyotrophic Lateral Sclerosis splits between interventional and observational designs.
68 interventional and 35 observational studies make up this index (66% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
103 total, page 3 of 3
R(+)PPX High Dose Treatment of ALS
Bennett, James P., Jr., M.D., Ph.D.
NCT00600873
The Use of Airway Clearance Devices in ALS
Cedars-Sinai Medical Center
NCT02682030
A Study of Protein Metabolism, Microbiome and Investigational Probiotic Use in Patients With ALS
Avera McKennan Hospital & University Health Center
NCT03324399
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 19 |
| Phase 2 | 21 |
| Phase 3 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on Amyotrophic Lateral Sclerosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Amyotrophic Lateral Sclerosis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Amyotrophic Lateral Sclerosis page
103 registered trials, 47 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 47 Amyotrophic Lateral Sclerosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Miami sponsors the most Amyotrophic Lateral Sclerosis trials on record, review their full trial history before evaluating a specific study. See University of Miami's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Amyotrophic Lateral Sclerosis condition card totals 103 registered trials; most-linked intervention Placebo; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.