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ClinicalTrials.gov 155 recruiting now official registry

Alzheimer Disease clinical trials

155 of 312 indexed Alzheimer Disease trials are currently recruiting.

312 US clinical trials · 155 currently recruiting

Alzheimer Disease is the subject of 312 registered US clinical trials on ClinicalTrials.gov, 155 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 104 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 13 of these trials.

The research picture

Alzheimer Disease has 312 registered US clinical trials, 155 of them open to new participants right now, about 50% of the total.

155
recruiting participants now
50%
of trials open to enrollment
26
in Phase 3–4 (later-stage)
13
top sponsor: Eli Lilly and Company
Phase 153Phase 251Phase 318Phase 48

Active & Recent Trials

312 total, page 7 of 7

COMPLETED NA 6 participants

In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Spanish Language Homes

University of California, Berkeley

NCT05159596

COMPLETED NA 6 participants

Non-invasive Blood-brain Barrier Opening in Alzheimer's Disease Patients Using Focused Ultrasound

Columbia University

NCT04118764

COMPLETED 4 participants

Feasibility - Infinitome

HealthPartners Institute

NCT04563767

COMPLETED Phase 1 4 participants

Research Involving Subjects With Parkinson's Disease, Alzheimer Disease and Healthy Controls

Institute for Neurodegenerative Disorders

NCT01461109

COMPLETED NA 3 participants

Home-based Transcranial Direct Current Stimulation (tDCS) for Behavioral Symptoms in Alzheimer's Disease and Related Dementias (ADRD)

The University of Texas Health Science Center, Houston

NCT05478681

COMPLETED NA 2 participants

Deep Brain Stimulation with LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease

University of California, Los Angeles

NCT03347084

COMPLETED 1 participants

Florbetaben PET Imaging in PPA

University of Chicago

NCT04720001

COMPLETED Phase 4

The Depression in Alzheimer's Disease Study (DIADS)

Johns Hopkins University

NCT00009191

COMPLETED Phase 3

Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type

Otsuka Pharmaceutical Development & Commercialization

NCT00041678

COMPLETED Phase 3

Serotonergic Pharmacotherapy for Agitation of Dementia

Bruce Pollock

NCT00009204

COMPLETED Phase 2

A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study)

National Institute on Aging (NIA)

NCT00004845

COMPLETED Phase 3

Evaluation of Galantamine in the Treatment of Alzheimer's Disease

Janssen

NCT00000172

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Phase Distribution

PhaseTrial count
Phase 1 53
Phase 2 51
Phase 3 18
Phase 4 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Alzheimer Disease Trial Landscape

312 indexed Alzheimer Disease studies · 155 recruiting (50%).

Phase mix: 26 late (III/IV) vs 104 early (I/II).

Top sponsor: Eli Lilly and Company (13 trials), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Alzheimer Disease?

PlainTrial tracks 312 US clinical trials for Alzheimer Disease, of which 155 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Alzheimer Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.