Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

Evaluation of Galantamine in the Treatment of Alzheimer's Disease

NCT00000172 · View on ClinicalTrials.gov ↗

Study Summary

Galantamine is an experimental drug being evaluated in the United States for the treatment of Alzheimer's disease. Results from previous clinical trials suggest that galantamine may improve cognitive performance in individuals with Alzheimer's disease. It is not a cure for Alzheimer's disease. Nerve cells in the brain responsible for memory and cognitive function communicate using a chemical called acetylcholine. Research has shown that deterioration of cells that produce acetylcholine in the brain affects thought processes. Galantamine is thought to work in two ways to increase the amount of acetylcholine available in the brain. It inhibits an enzyme that breaks down acetylcholine and it also stimulates the nicotinic receptors in the brain to release more acetylcholine.

Conditions Studied

Interventions

  • DRUG Galantamine

Study Locations (20)

California

  • East Bay Neurology — Berkeley
  • University of Southern California — Los Angeles
  • N. County Neurology Assoc. — Oceanside
  • University of California Irvine Medical Center — Orange
  • Pacific Research Network (PRN) — San Diego
  • Affiliated Research Institute — San Diego
  • INC — San Diego

Florida

  • Ocala Neurodiagnostic Center — Ocala
  • Psychiatric Institute of Florida — Orlando
  • Neurological Research Institute of Sarasota, PA — Sarasota
  • Suncoast Neuroscience Associates, Inc. — St. Petersburg
  • Premiere Research Institute — West Palm Beach

Connecticut

  • Geriatric and Adult Psychiatry — Hamden
  • Yale University, School of Medicine — New Haven

Illinois

  • Chicago Center for Clinical Research — Chicago
  • OSF Center for Senior Health — Peoria

Alabama

  • University of Alabama, Birmingham — Birmingham

Arizona

  • James L. Frey, M.D., Ltd. — Scottsdale

Colorado

  • The Denver Center for Medical Research — Denver

Indiana

  • Indiana Alzheimer's University Clinic — Indianapolis

Trial Details

FieldValue
Phase Phase 3

Sponsor

Janssen

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00000172

The ClinicalTrials.gov registry entry for NCT00000172 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is Janssen, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Alzheimer Disease appearing as the primary indexed condition, and to 1 intervention — of which Galantamine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00000172 reports 20 study locations spanning 8 distinct geographic areas — top geographies include California, Florida, Connecticut. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00000172 about?

NCT00000172 is a clinical study titled "Evaluation of Galantamine in the Treatment of Alzheimer's Disease". Galantamine is an experimental drug being evaluated in the United States for the treatment of Alzheimer's disease. Results from previous clinical trials suggest that galantamine may improve cognitive performance in individuals with Alzheimer's disease. It is not a cure for Alzheimer's disease. Nerve...

What is the current status of trial NCT00000172?

This trial is currently completed. It is a Phase 3 study.

What conditions does trial NCT00000172 study?

This clinical trial studies the following conditions: Alzheimer Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00000172?

The interventions under investigation include: Galantamine (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00000172?

This trial is sponsored by Janssen, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00000172 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial