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ClinicalTrials.gov 45 recruiting now official registry

Advanced Cancer clinical trials

45 of 123 indexed Advanced Cancer trials are currently recruiting.

123 US clinical trials · 45 currently recruiting

Advanced Cancer is the subject of 123 registered US clinical trials on ClinicalTrials.gov, 45 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 85 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 19 of these trials.

The research picture

Advanced Cancer has 123 registered US clinical trials, 45 of them open to new participants right now, about 37% of the total.

45
recruiting participants now
37%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
19
top sponsor: M.D. Anderson Cancer Center
Phase 171Phase 214Phase 32

Active & Recent Trials

123 total, page 3 of 3

COMPLETED NA 42 participants

Feasibility, Acceptability and Preliminary Effects of the Spiritual Care Assessment and Intervention

Indiana University

NCT03823313

COMPLETED Phase 1 39 participants

Safety Study of FP-1039 To Treat Cancer

Five Prime Therapeutics

NCT00687505

COMPLETED Phase 1 39 participants

A Bioequivalence Study of Docetaxel for Injectable Emulsion (ANX-514) in Patients With Advanced Cancer

Mast Therapeutics

NCT00664170

COMPLETED Phase 1 37 participants

A Trial of ZL-1201 in Subjects With Advanced Cancer

Zai Lab (Shanghai) Co.

NCT04257617

COMPLETED Phase 1 36 participants

A Safety and Pharmacokinetic Study of TRX-818 Administered Orally to Patients With Advanced Cancer

TaiRx

NCT02507544

COMPLETED Phase 2 30 participants

Olanzapine for the Treatment of Chronic Nausea and/or Vomiting in Advanced Cancer Patients

University of Alabama at Birmingham

NCT03137121

COMPLETED Phase 1 30 participants

A Protocol for the Safety and Tolerance of Intravenous Isophosphoramide Mustard (IPM) in Patients With Advanced Cancer

Alaunos Therapeutics

NCT00421135

COMPLETED Phase 1 30 participants

Phase 1 Study of ZIO-201-T in Combination With Doxorubicin in Solid Tumors

Alaunos Therapeutics

NCT00608803

COMPLETED Phase 1 29 participants

A Dose-Escalation Study in Participants With Advanced Cancer

Eli Lilly and Company

NCT01524224

COMPLETED Phase 1 28 participants

A Study to Evaluate the Safety and Pharmacokinetics of CDX-0158 in Adult Patients With Advanced Solid Tumors

Celldex Therapeutics

NCT02642016

COMPLETED Phase 1 27 participants

Safety Study of MKC-1 Combined With Pemetrexed to Treat Advanced Cancer and Non-Small Cell Lung Cancer

CASI Pharmaceuticals

NCT00408226

COMPLETED NA 24 participants

Telephone-Based Mindfulness CBT for Patients in Community Settings With Advanced Cancer

Duke University

NCT03285633

COMPLETED Phase 1 24 participants

Study of ASP7517 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors Expressing WT1 Antigen

Astellas Pharma Global Development

NCT04837196

COMPLETED Phase 1 23 participants

A Study of the Safety and PK of PCS6422 (Eniluracil) with Capecitabine in Patients with Advanced, Refractory GI Tract Tumors

Processa Pharmaceuticals

NCT04861987

COMPLETED NA 22 participants

Behavioral Activation-Led Activity Engagement for Cancer Empowerment

University of Pittsburgh

NCT06796608

COMPLETED Phase 2 20 participants

DM-CHOC-PEN for Brain Tumors in AYA Subjects

DEKK-TEC

NCT03668847

COMPLETED Phase 1 19 participants

DM-CHOC-PEN Plus Radiation for Brain Tumors

DEKK-TEC

NCT03371004

COMPLETED Early Phase 1 15 participants

Temsirolimus In Phase 0

M.D. Anderson Cancer Center

NCT01417065

COMPLETED 11 participants

An Ancillary Pilot Trial Using Whole Genome Sequencing In Patients With Advance Refractory Cancer

Scottsdale Healthcare

NCT01443390

COMPLETED NA 10 participants

STAMP+CBT mHealth for Cancer Pain

Dana-Farber Cancer Institute

NCT05403801

COMPLETED NA 7 participants

The Science of the Art of Palliative Care

Dartmouth-Hitchcock Medical Center

NCT05137782

COMPLETED Phase 1 3 participants

FLT-PET as an Imaging Biomarker With Temsirolimus, Topotecan, and Bortezomib

M.D. Anderson Cancer Center

NCT01143779

COMPLETED NA 1 participants

Collaborative Care Intervention for Cancer Caregivers

University of Pittsburgh

NCT02944136

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Phase Distribution

PhaseTrial count
Phase 1 71
Phase 2 14
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Advanced Cancer Trial Landscape

123 indexed Advanced Cancer studies · 45 recruiting (37%).

Phase mix: 2 late (III/IV) vs 85 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (19 trials), 9 others listed. 23 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Advanced Cancer?

PlainTrial tracks 123 US clinical trials for Advanced Cancer, of which 45 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Advanced Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.