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NCT01964859 · ClinicalTrials.gov registry record · Phase 2
Feasibility Study for Fibroblast Autologous Skin Grafts
A Phase 2 study of Wounds and Injuries, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT01964859: Recruiting Phase 2 study of Wounds and Injuries, sponsored by Johns Hopkins University.
NCT01964859 is a Phase 2 study of Wounds and Injuries that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 80 participants, below the 501-participant average among 27 other Wounds and Injuries trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01964859, a Phase 2 study of Wounds and Injuries, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
This research is being done to determine if investigators can change skin from one type to another. Specifically, investigators are interested in making normal skin into the thicker skin found on our palms and soles.
Primary Outcome
Volar keratinocytes have larger area of the cytoplasm. We will quantitate the area of cytoplasm of non-volar keratinocytes to see if they increase selectively with volar fibroblasts as opposed to other fibroblasts injections or vehicle. The change in the area of cytoplasm of non-volar keratinocytes will be measured. The units of this measurement are a ratio of cytoplasmic area to total cellular area as a control.
Conditions Studied
Interventions
- BIOLOGICAL autologous skin fibroblasts
- BIOLOGICAL Filler Product
Study Locations (1)
Maryland
- Johns Hopkins School of Medicine, Dermatology Department - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2015-01-07 |
| Est. Completion | 2028-11-01 |
| Phase | Phase 2 |
What NCT01964859 shows while recruiting
NCT01964859 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 501-participant average among 27 other Wounds and Injuries trials with a reported enrollment target (84% lower).
The record links to 1 condition, with Wounds and Injuries appearing as the primary indexed condition, and to 2 interventions - of which autologous skin fibroblasts is the first listed.
NCT01964859 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT01964859 about?
NCT01964859 is a clinical study titled "Feasibility Study for Fibroblast Autologous Skin Grafts". This research is being done to determine if investigators can change skin from one type to another. Specifically, investigators are interested in making normal skin into the thicker skin found on our palms and soles.
What is the current status of trial NCT01964859?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2015-01-07. Estimated completion is 2028-11-01.
What conditions does trial NCT01964859 study?
This clinical trial studies the following conditions: Wounds and Injuries.
What interventions are being tested in trial NCT01964859?
The interventions under investigation include: autologous skin fibroblasts (BIOLOGICAL), Filler Product (BIOLOGICAL).
Who is sponsoring clinical trial NCT01964859?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01964859 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Wounds and Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01964859's enrollment target sits among peer trials
80 20th of 27 higher than 8 of 27 other Wounds and Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Wounds and Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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