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NCT01803451 · ClinicalTrials.gov registry record · Early Phase 1
Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
A Early Phase 1 study of Post Bariatric Surgery, sponsored by The University of Texas Health Science Center at San Antonio.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 80
- Enrollment target
- 2
- Study locations
NCT01803451 is a Early Phase 1 study of Post Bariatric Surgery that is actively recruiting participants, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 80 participants. The trial reports 2 study locations across 1 state.
The verdict
NCT01803451, a Early Phase 1 study of Post Bariatric Surgery, is actively recruiting participants, sponsored by The University of Texas Health Science Center at San Antonio.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 80 participants
- Enrollment target
- 2
- Study locations
Study Summary
The overall goal of this project is to understand the mechanisms by which gastric bypass surgery improves glucose metabolism. The central hypothesis guiding this project is that the reconfiguration of intestinal transit with the Roux-en-Y will increase the release of insulinotropic GI hormones, termed incretins that improve insulin secretion and glucose metabolism. The study is divided into three specific aims. 1. To determine the role of incretin hormones on insulin secretion in patients with gastric bypass surgery using intravenous-oral hyperglycemic clamp. 2. To compare incretin effect and glucose tolerance among patient who suffer from hypoglycemia after RYGB and asymptomatic surgical and non-surgical individuals. 3. To quantify the contribution of GLP-1 to incretin effect enhancement following surgery.
Conditions Studied
Interventions
- DRUG exendin-(9-39)
- DRUG exendin -(9-39)
Study Locations (2)
Texas
- Texas Diabetes Institute - University Health System - San Antonio
- South Texas Veterans Health Care System - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2005-11 |
| Est. Completion | 2027-08 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01803451
The ClinicalTrials.gov registry entry for NCT01803451 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The University of Texas Health Science Center at San Antonio, which has 378 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Post Bariatric Surgery appearing as the primary indexed condition, and to 2 interventions - of which exendin-(9-39) is the first listed.
NCT01803451 reports 2 study locations spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT01803451 about?
NCT01803451 is a clinical study titled "Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass". The overall goal of this project is to understand the mechanisms by which gastric bypass surgery improves glucose metabolism. The central hypothesis guiding this project is that the reconfiguration of intestinal transit with the Roux-en-Y will increase the release of insulinotropic GI hormones, ter...
What is the current status of trial NCT01803451?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 80 participants. The study started on 2005-11. Estimated completion is 2027-08.
What conditions does trial NCT01803451 study?
This clinical trial studies the following conditions: Post Bariatric Surgery.
What interventions are being tested in trial NCT01803451?
The interventions under investigation include: exendin-(9-39) (DRUG), exendin -(9-39) (DRUG).
Who is sponsoring clinical trial NCT01803451?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01803451 being conducted?
This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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