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NCT01803451 · ClinicalTrials.gov registry record · Early Phase 1
Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
A Early Phase 1 study of Post Bariatric Surgery, sponsored by The University of Texas Health Science Center at San Antonio.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 80
- Enrollment target
- 2
- Study locations
NCT01803451: Recruiting Early Phase 1 study of Post Bariatric Surgery, sponsored by The University of Texas Health Science Center at San Antonio.
NCT01803451 is a Early Phase 1 study of Post Bariatric Surgery that is actively recruiting participants, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 80 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (51% higher). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01803451, a Early Phase 1 study of Post Bariatric Surgery, is actively recruiting participants, sponsored by The University of Texas Health Science Center at San Antonio.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 80 participants
- Enrollment target
- 2
- Study locations
Study Summary
The overall goal of this project is to understand the mechanisms by which gastric bypass surgery improves glucose metabolism. The central hypothesis guiding this project is that the reconfiguration of intestinal transit with the Roux-en-Y will increase the release of insulinotropic GI hormones, termed incretins that improve insulin secretion and glucose metabolism. The study is divided into three specific aims. 1. To determine the role of incretin hormones on insulin secretion in patients with gastric bypass surgery using intravenous-oral hyperglycemic clamp. 2. To compare incretin effect and glucose tolerance among patient who suffer from hypoglycemia after RYGB and asymptomatic surgical and non-surgical individuals. 3. To quantify the contribution of GLP-1 to incretin effect enhancement following surgery.
Conditions Studied
Interventions
- DRUG exendin-(9-39)
- DRUG exendin -(9-39)
Study Locations (2)
Texas
- Texas Diabetes Institute - University Health System - San Antonio
- South Texas Veterans Health Care System - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2005-11 |
| Est. Completion | 2027-08 |
| Phase | Early Phase 1 |
What NCT01803451 shows while recruiting
NCT01803451 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (51% higher).
The record links to 1 condition, with Post Bariatric Surgery appearing as the primary indexed condition, and to 2 interventions - of which exendin-(9-39) is the first listed.
NCT01803451 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT01803451 about?
NCT01803451 is a clinical study titled "Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass". The overall goal of this project is to understand the mechanisms by which gastric bypass surgery improves glucose metabolism. The central hypothesis guiding this project is that the reconfiguration of intestinal transit with the Roux-en-Y will increase the release of insulinotropic GI hormones, ter...
What is the current status of trial NCT01803451?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 80 participants. The study started on 2005-11. Estimated completion is 2027-08.
What conditions does trial NCT01803451 study?
This clinical trial studies the following conditions: Post Bariatric Surgery.
What interventions are being tested in trial NCT01803451?
The interventions under investigation include: exendin-(9-39) (DRUG), exendin -(9-39) (DRUG).
Who is sponsoring clinical trial NCT01803451?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01803451 being conducted?
This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Post Bariatric Surgery
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01803451's enrollment target sits among peer trials
80 271st of 2000 higher than 1,704 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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