Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05102929 · ClinicalTrials.gov registry record · NA
Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia
A NA study of Schizophrenia, sponsored by Fabio Ferrarelli.
- Recruiting
- Registry status
- NA
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT05102929: Recruiting NA study of Schizophrenia, sponsored by Fabio Ferrarelli.
NCT05102929 is a NA study of Schizophrenia that is actively recruiting participants, run by Fabio Ferrarelli. The registered enrollment target is 75 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05102929, a NA study of Schizophrenia, is actively recruiting participants, sponsored by Fabio Ferrarelli.
- RECRUITING
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will investigate the effects of intermittent Theta Burst Stimulation (iTBS) on natural oscillatory frequency of the dorsolateral prefrontal cortex (DLPFC) and working memory in early-course schizophrenia (EC-SCZ). Transcranial magnetic stimulation (TMS) will be used to evoke oscillatory activity, and EEG will record the responses of EC-SCZ participants. A working memory task will also be incorporated in order to determine how DLPFC natural frequency (NF) is related to working memory performance. iTBS (active or sham) will be administered, then the oscillatory activity of DLPFC and working memory performance will be reassessed. The overarching goal is to determine whether iTBS can acutely enhance the oscillatory activity of the DLPFC and to evaluate the relationship between changes in the DLPFC and working memory performance.
Primary Outcome
The difference in prefrontal natural frequency (DLPFC NF) between pre- and post- intermittent Theta Burst Stimulation (iTBS) in EC-SCZ patients
Conditions Studied
Interventions
- DEVICE active intermittent Theta Burst Stimulation (iTBS)
- DEVICE sham intermittent Theta Burst Stimulation (iTBS)
Study Locations (1)
Pennsylvania
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2021-11-05 |
| Est. Completion | 2026-08 |
| Phase | NA |
What NCT05102929 shows while recruiting
NCT05102929 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (66% lower).
The record links to 1 condition, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which active intermittent Theta Burst Stimulation (iTBS) is the first listed.
NCT05102929 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05102929 about?
NCT05102929 is a clinical study titled "Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia". This study will investigate the effects of intermittent Theta Burst Stimulation (iTBS) on natural oscillatory frequency of the dorsolateral prefrontal cortex (DLPFC) and working memory in early-course schizophrenia (EC-SCZ). Transcranial magnetic stimulation (TMS) will be used to evoke oscillatory a...
What is the current status of trial NCT05102929?
This trial is currently recruiting. It is a NA study. The enrollment target is 75 participants. The study started on 2021-11-05. Estimated completion is 2026-08.
What conditions does trial NCT05102929 study?
This clinical trial studies the following conditions: Schizophrenia.
What interventions are being tested in trial NCT05102929?
The interventions under investigation include: active intermittent Theta Burst Stimulation (iTBS) (DEVICE), sham intermittent Theta Burst Stimulation (iTBS) (DEVICE).
Who is sponsoring clinical trial NCT05102929?
This trial is sponsored by Fabio Ferrarelli, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05102929 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Schizophrenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05102929's enrollment target sits among peer trials
75 171st of 315 higher than 144 of 315 other Schizophrenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Taking Action for College Students
RECRUITING · NA
-
Getting Out of the House: Using Behavioral Activation to Increase Community Participation
RECRUITING · NA
-
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)
RECRUITING · NA
-
Cerebellar Modulation of Cognition in Psychosis
RECRUITING · NA
-
TMS for Inhibition Enhancement in Schizophrenia
RECRUITING · NA
-
Decision-Making in Schizophrenia: A Combined Neuroimaging and Experience Sampling Study
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01535430 · 75 participants
Assessment of Eloquent Function in Brain Tumor Patients
- NCT01542879 · 75 participants · Phase 1
Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer
- NCT02232191 · 75 participants · Phase 2
Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients
- NCT02754544 · 75 participants · NA
Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI