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NCT02359825 · ClinicalTrials.gov registry record · Phase 1
Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function
A Phase 1 study of Peripheral Nerve Injury, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT02359825: Recruiting Phase 1 study of Peripheral Nerve Injury, sponsored by Vanderbilt University Medical Center.
NCT02359825 is a Phase 1 study of Peripheral Nerve Injury that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 18 participants, below the 37-participant average among 3 other Peripheral Nerve Injury trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02359825, a Phase 1 study of Peripheral Nerve Injury, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
Current strategies for peripheral nerve repair are severely limited. Even with current techniques, it can take months for regenerating axons to reach denervated target tissues when injuries are proximally located. This inability to rapidly restore the loss of function after axonal injury continues to produce poor clinical outcomes. The investigators propose testing the efficacy and safety of a combination therapy: polyethylene glycol (PEG) assisted axonal fusion technique to repair peripheral nerve injuries in humans.
Primary Outcome
Medical Research Council Classificatoin (MRCC)
Conditions Studied
Interventions
- DRUG Polyethylene glycol (PEG)
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2019-09-19 |
| Est. Completion | 2028-07-01 |
| Phase | Phase 1 |
What NCT02359825 shows while recruiting
NCT02359825 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 37-participant average among 3 other Peripheral Nerve Injury trials with a reported enrollment target (51% lower).
The record links to 1 condition, with Peripheral Nerve Injury appearing as the primary indexed condition, and to 1 intervention - of which Polyethylene glycol (PEG) is the first listed.
NCT02359825 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT02359825 about?
NCT02359825 is a clinical study titled "Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function". Current strategies for peripheral nerve repair are severely limited. Even with current techniques, it can take months for regenerating axons to reach denervated target tissues when injuries are proximally located. This inability to rapidly restore the loss of function after axonal injury continues t...
What is the current status of trial NCT02359825?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2019-09-19. Estimated completion is 2028-07-01.
What conditions does trial NCT02359825 study?
This clinical trial studies the following conditions: Peripheral Nerve Injury.
What interventions are being tested in trial NCT02359825?
The interventions under investigation include: Polyethylene glycol (PEG) (DRUG).
Who is sponsoring clinical trial NCT02359825?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02359825 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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