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NCT02359825 · ClinicalTrials.gov registry record · Phase 1

Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function

A Phase 1 study of Peripheral Nerve Injury, sponsored by Vanderbilt University Medical Center.

Recruiting
Registry status
Phase 1
Development phase
18
Enrollment target
1
Study location

NCT02359825 is a Phase 1 study of Peripheral Nerve Injury that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 18 participants, below the 37-participant average among 3 other Peripheral Nerve Injury trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02359825, a Phase 1 study of Peripheral Nerve Injury, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.

RECRUITING
Registry status
Phase 1
Development phase
18 participants
Enrollment target
1
Study location

Study Summary

Current strategies for peripheral nerve repair are severely limited. Even with current techniques, it can take months for regenerating axons to reach denervated target tissues when injuries are proximally located. This inability to rapidly restore the loss of function after axonal injury continues to produce poor clinical outcomes. The investigators propose testing the efficacy and safety of a combination therapy: polyethylene glycol (PEG) assisted axonal fusion technique to repair peripheral nerve injuries in humans.

Conditions Studied

Interventions

  • DRUG Polyethylene glycol (PEG)

Study Locations (1)

Tennessee

  • Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2019-09-19
Est. Completion 2028-07-01
Phase Phase 1

What the Registry Record Tells You About NCT02359825

The ClinicalTrials.gov registry entry for NCT02359825 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 37-participant average among 3 other Peripheral Nerve Injury trials with a reported enrollment target (51% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Peripheral Nerve Injury appearing as the primary indexed condition, and to 1 intervention - of which Polyethylene glycol (PEG) is the first listed.

NCT02359825 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT02359825 about?

NCT02359825 is a clinical study titled "Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function". Current strategies for peripheral nerve repair are severely limited. Even with current techniques, it can take months for regenerating axons to reach denervated target tissues when injuries are proximally located. This inability to rapidly restore the loss of function after axonal injury continues t...

What is the current status of trial NCT02359825?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2019-09-19. Estimated completion is 2028-07-01.

What conditions does trial NCT02359825 study?

This clinical trial studies the following conditions: Peripheral Nerve Injury.

What interventions are being tested in trial NCT02359825?

The interventions under investigation include: Polyethylene glycol (PEG) (DRUG).

Who is sponsoring clinical trial NCT02359825?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02359825 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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