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NCT05933707 · ClinicalTrials.gov registry record · NA
Small Extracellular Vesicles and Insulin Action
A NA study of Obesity and Insulin Resistance, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- NA
- Development phase
- 72
- Enrollment target
- 1
- Study location
NCT05933707: Recruiting NA study of Obesity and Insulin Resistance, sponsored by Washington University School of Medicine.
NCT05933707 is a NA study of Obesity and Insulin Resistance that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 72 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05933707, a NA study of Obesity and Insulin Resistance, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- NA
- Development phase
- 72 participants
- Enrollment target
- 1
- Study location
Study Summary
The goals of this research study are to: 1) understand why some people with obesity are protected from developing conditions such as type 2 diabetes and cardiovascular disease while others are more likely to develop obesity-related conditions; 2) assess the effect of small extracellular vesicles (sEVs also called exosomes), obtained from human participants, on metabolic function in cultured cells and in mice.
Primary Outcome
Exosomes obtained from the plasma and adipose tissue of metabolically healthy lean participants, and participants with metabolically healthy or metabolically unhealthy obesity will be tested in cultured cells and mice to determine their effect on insulin sensitivity.
Conditions Studied
Interventions
- BEHAVIORAL People with Metabolically Unhealthy Obesity - Low Calorie Diet
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2023-06-08 |
| Est. Completion | 2029-09-01 |
| Phase | NA |
What NCT05933707 shows while recruiting
NCT05933707 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (91% lower).
The record links to 4 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which People with Metabolically Unhealthy Obesity - Low Calorie Diet is the first listed.
NCT05933707 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT05933707 about?
NCT05933707 is a clinical study titled "Small Extracellular Vesicles and Insulin Action". The goals of this research study are to: 1) understand why some people with obesity are protected from developing conditions such as type 2 diabetes and cardiovascular disease while others are more likely to develop obesity-related conditions; 2) assess the effect of small extracellular vesicles (sE...
What is the current status of trial NCT05933707?
This trial is currently recruiting. It is a NA study. The enrollment target is 72 participants. The study started on 2023-06-08. Estimated completion is 2029-09-01.
What conditions does trial NCT05933707 study?
This clinical trial studies the following conditions: Obesity, Insulin Resistance, Metabolically Healthy Obesity, Obesity, Metabolically Benign.
What interventions are being tested in trial NCT05933707?
The interventions under investigation include: People with Metabolically Unhealthy Obesity - Low Calorie Diet (BEHAVIORAL).
Who is sponsoring clinical trial NCT05933707?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05933707 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05933707's enrollment target sits among peer trials
72 583rd of 1053 higher than 462 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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