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NCT03523975 · ClinicalTrials.gov registry record · Phase 1

Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma

A Phase 1 study of Mantle Cell Lymphoma, sponsored by City of Hope Medical Center.

Recruiting
Registry status
Phase 1
Development phase
28
Enrollment target
3
Study locations

NCT03523975 is a Phase 1 study of Mantle Cell Lymphoma that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 28 participants, below the 104-participant average among 102 other Mantle Cell Lymphoma trials with a reported enrollment target (73% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT03523975, a Phase 1 study of Mantle Cell Lymphoma, is actively recruiting participants, sponsored by City of Hope Medical Center.

RECRUITING
Registry status
Phase 1
Development phase
28 participants
Enrollment target
3
Study locations

Study Summary

The purpose of this study is to determine if giving an experimental drug called venetoclax in combination with lenalidomide and rituximab is safe and effective for treating people with Mantle Cell Lymphoma (MCL).

Conditions Studied

Mantle Cell Lymphoma

Interventions

  • DRUG Venetoclax
  • DRUG Rituximab
  • DRUG Lenalidomide

Study Locations (3)

California

  • City of Hope Medical center - Duarte

Michigan

  • University of Michigan - Ann Arbor

Ohio

  • The Ohio State University Comprehensive Cancer Center - Columbus

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2018-12-24
Est. Completion 2027-06-24
Phase Phase 1

Sponsor

City of Hope Medical Center

582 total trials

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What the Registry Record Tells You About NCT03523975

The ClinicalTrials.gov registry entry for NCT03523975 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 104-participant average among 102 other Mantle Cell Lymphoma trials with a reported enrollment target (73% lower). The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Mantle Cell Lymphoma appearing as the primary indexed condition, and to 3 interventions - of which Venetoclax is the first listed.

NCT03523975 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Michigan, Ohio.

Frequently Asked Questions

What is clinical trial NCT03523975 about?

NCT03523975 is a clinical study titled "Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma". The purpose of this study is to determine if giving an experimental drug called venetoclax in combination with lenalidomide and rituximab is safe and effective for treating people with Mantle Cell Lymphoma (MCL).

What is the current status of trial NCT03523975?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2018-12-24. Estimated completion is 2027-06-24.

What conditions does trial NCT03523975 study?

This clinical trial studies the following conditions: Mantle Cell Lymphoma.

What interventions are being tested in trial NCT03523975?

The interventions under investigation include: Venetoclax (DRUG), Rituximab (DRUG), Lenalidomide (DRUG).

Who is sponsoring clinical trial NCT03523975?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03523975 being conducted?

This trial has 3 study locations across California, Michigan, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.